A5081489497- Osteoarthritis Treatment and Mechanisms
- Orthopaedic implants and arthroplasty
- Total Knee Arthroplasty Outcomes
- Bone health and osteoporosis research
- Cellular Mechanics and Interactions
- Microfluidic and Bio-sensing Technologies
- Orthopedic Infections and Treatments
- Dental Implant Techniques and Outcomes
- 3D Printing in Biomedical Research
- Bone Tissue Engineering Materials
- Muscle activation and electromyography studies
- Bone fractures and treatments
- Injury Epidemiology and Prevention
- Automotive and Human Injury Biomechanics
- Musculoskeletal pain and rehabilitation
- Shoulder Injury and Treatment
- Elasticity and Material Modeling
- Periodontal Regeneration and Treatments
- Knee injuries and reconstruction techniques
- Hip disorders and treatments
- Bone and Joint Diseases
- Growth Hormone and Insulin-like Growth Factors
- Infrared Thermography in Medicine
- Spine and Intervertebral Disc Pathology
- Traffic and Road Safety
Oregon Health & Science University
2009-2023
University of Oregon
2021-2023
Bioengineering (Switzerland)
2020
U.S. Air Force Institute of Technology
2015
Portland State University
2006-2014
Oregon State University
2002-2012
American Society of Mechanical Engineers
2006-2009
Worcester Polytechnic Institute
1997-2008
Tufts University
2000
University of Massachusetts Chan Medical School
2000
As a result of the low yield cartilage from primary patient harvests and high demand for autologous reconstructive surgery structural repair, explant must be augmented by tissue engineering techniques. In this study, chondrocytes seeded on PLLA/PGA scaffolds in static culture direct perfusion bioreactor were biochemically histologically analyzed to determine effects fluid flow media pH matrix assembly. A gradual change was maintained within 7.4−6.96 over 2 weeks compared more rapid decrease...
ABSTRACT Background: In cases of reduced alveolar bone height, implants short length (10 mm or less) may be employed although there is a perceived risk that because their small stature they will unable to tolerate occlusal loads and fail osseointegrate. Purpose: This report describes an analysis prospective multicenter clinical studies evaluating the for failure short‐length implants, comparing dual acid‐etched (DAE) Osseotite® (Implant Innovations, Inc., Palm Beach Gardens, FL, USA)...
Abstract A large‐deflection elasticity model was used to describe the mechanical behavior of cartilaginous tissues during three‐point bending tests. Force‐deflection curves were measured for 20‐mm long × 4‐mm wide ≈1‐mm thick strips porcine auricular and costal cartilage. Using a least‐squares method with elastic modulus in as only adjustable parameter, data fit based on von Karman theory large deflection plates. This described well, an average RMS error 14.8% R 2 value 0.98. this method,...
The mechanical performance of cancellous bone is characterized using experiments which apply linear poroelasticity theory. It hypothesized that the anisotropic organization solid and pore volumes can be physically separately (no deformable boundary interactive effects) within same sample. Due to its spongy construction, in vivo function or trabecular dependent upon fluid materials may interact a hydraulic, convective fashion during functional loading. This project provides insight into...
Chiari malformation is defined as herniation of the cerebellar tonsils through foramen magnum, also known tonsillar ectopia (CTE). CTE may become symptomatic following whiplash trauma. The purpose present study was to assess frequency in traumatic vs non-traumatic populations.Case-control.Cervical MRI scans for 1200 neck pain patients were reviewed; 600 trauma (cases) and non-trauma (controls). Half groups scanned a recumbent position half an upright position. Two radiologists interpreted...
A system was refined for the determination of bulk ultrasonic wave propagation velocity in small cortical bone specimens. Longitudinal and shear propagations were measured using ceramic, piezoelectric 20 5 MHz transducers, respectively. Results pulse transmission technique via measurement delay time. The precision accuracy quantified specimens polyoxymethylene, polystyrene-butadiene, high-density polyethylene. These polymeric materials had known acoustic properties, similarity velocities to...
Summary Basic research in canine mechanics must be performed to better understand the forces and moments appendicular skeleton withstand. This type of may allow surgeons make substantial advances total joint replacement fracture fixation design enhance our understanding bone remodeling occurrence relation exercise trauma. In study, craniocaudal bending stiffness, mediolateral axial compressive torsional stiffness humerus, femur, radius, tibia dogs was determined, using nondestructive...
Advancements in technologies for assessing biomechanics at the cellular level have led to discoveries mechanotransduction and investigation of cell mechanics as a biomarker disease. With recent development an integrated optical tweezer with micron resolution particle image velocimetry, opportunity apply controlled multiaxial stresses suspended single cells is available (Neve, N., Lingwood, J. K., Zimmerman, J., Kohles, S. S., Tretheway, D. C., 2008, "The muPIVOT: An Integrated Particle Image...
In the knee joint, interactions between instantaneous kinetics and kinematics associated with ligamentous articular tissues are not fully understood. These structures may be represented by screw axis ($) (ISA) static force vectors ($'). Geometric changes to joint structure affecting motion have been explained, especially after surgical reconstruction replacement procedures. The ISA offers a joint-characterisation approach, which is dependent on combined forces of ligaments, contacts muscles....
Physiologic regulation of extracellular matrix (ECM) in articular cartilage tissue is controlled by cellular and molecular mechanisms which are not fully understood. It has been observed that the synthesis ECM structural molecules, glycosaminoglycan collagen promoted growth factors such as IGF-1 TGF-β. Concomitant degradation a variety cytokines IL-1. The clinical need for reparative therapies linked with its poor intrinsic healing capacity. following modelling approach was applied to...
Background: Ligaments and cartilage contact contribute to the mechanical constraints in knee joints. However, precise influence of these structural components on joint movement, especially when are computed using inverse dynamics solutions, is not clear. Methods: We present a characterization connections between infinitesimal twist tibia femur due restraining forces specific tissue that engaged responsible for such motion. These include anterior cruciate, posterior medial collateral, lateral...