A5102813919- Nanoplatforms for cancer theranostics
- Electrocatalysts for Energy Conversion
- Photoacoustic and Ultrasonic Imaging
- Nanoparticle-Based Drug Delivery
- Fuel Cells and Related Materials
- Nanowire Synthesis and Applications
- Photodynamic Therapy Research Studies
- Advanced battery technologies research
- Quantum Dots Synthesis And Properties
- Catalytic Processes in Materials Science
- Covalent Organic Framework Applications
- Nanomaterials for catalytic reactions
- Graphene and Nanomaterials Applications
- GaN-based semiconductor devices and materials
- Graphene research and applications
- Extracellular vesicles in disease
- 2D Materials and Applications
- Advanced Nanomaterials in Catalysis
- Advanced biosensing and bioanalysis techniques
- Advanced Photocatalysis Techniques
- CO2 Reduction Techniques and Catalysts
- Ga2O3 and related materials
- Molecular Junctions and Nanostructures
- ZnO doping and properties
- RNA Interference and Gene Delivery
Rice University
2012-2025
Paul Drude Institute for Solid State Electronics
2016-2023
Universidad Politécnica de Madrid
2023
Forschungsverbund Berlin
2016-2023
Shenzhen Institutes of Advanced Technology
2013-2017
Chinese Academy of Sciences
2013-2017
Institute for Biomedicine
2014-2017
Ocean University of China
2008-2012
Inner Mongolia Agricultural University
2008
An active cell membrane-camouflaged nanoparticle, owning to membrane antigens and structure, can achieve special properties such as specific recognition, long blood circulation, immune escaping. Herein, we reported a cancer membrane-cloaked nanoparticle system theranostic nanoplatform. The biomimetic nanoparticles (indocyanine green (ICG)-loaded membrane-coated nanoparticles, ICNPs) exhibit core-shell nanostructure consisting of an ICG-polymeric core shell. ICNPs demonstrated homologous...
Phototherapy, including photodynamic therapy (PDT) and photothermal (PTT), is a light-activated local treatment modality that under intensive preclinical clinical investigations for cancer. To enhance the efficiency of phototherapy reduce light-associated side effects, it highly desirable to improve drug accumulation precision guided efficient conversion absorbed light energy reactive oxygen species (ROS) hyperthermia. In present study, programmed assembly strategy was developed preparation...
Abstract Oxygen reduction reaction towards hydrogen peroxide (H 2 O ) provides a green alternative route for H production, but it lacks efficient catalysts to achieve high selectivity and activity simultaneously under industrial-relevant production rates. Here we report boron-doped carbon (B-C) catalyst which can overcome this activity-selectivity dilemma. Compared the state-of-the-art oxidized catalyst, B-C presents enhanced (saving more than 210 mV overpotential) currents (up 300 mA cm −2...
Achieving efficient and durable nonprecious hydrogen evolution reaction (HER) catalysts for scaling up alkaline water/seawater electrolysis is desirable but remains a significant challenge. Here, heterogeneous Ni-MoN catalyst consisting of Ni MoN nanoparticles on amorphous nanorods that can sustain large-current-density HER with outstanding performance demonstrated. The hierarchical nanorod-nanoparticle structure, along large surface area multidimensional boundaries/defects endows the...
Different nanoscale fillers have been used to create composite fluids for applications such as thermal management. The ever increasing loads in now require advanced operational fluids, example, high conductivity dielectric oils transformers. These excellent filler dispersion, conduction, but also electrical insulation. Such that conform this thermal/electrical requirement, and yet remain highly suspended stable state, not synthesized. We report here the synthesis characterization of...
Atom-thin transition metal dichalcogenides (TMDs) have emerged as fascinating materials and key structures for electrocatalysis. So far, their edges, dopant heteroatoms defects been intensively explored active sites the hydrogen evolution reaction (HER) to split water. However, grain boundaries (GBs), a type of in TMDs, overlooked due low density large structural variations. Here, we demonstrate synthesis wafer-size atom-thin TMD films with an ultra-high-density GBs, up ~1012 cm-2. We...
Photoacoustic (PA) imaging and photothermal therapy (PTT) as light-induced theranostic platforms have been attracted much attention in recent years. However, the development of highly efficient integrated phototheranostic nanoagents for amplifying PA PTT treatments poses great challenges. Here, we report a novel nanoagent using indocyanine green-loaded polydopamine-reduced graphene oxide nanocomposites (ICG-PDA-rGO) with effects cancer theranostics. The results demonstrate that PDA layer...
Developing non-precious catalysts with long-term catalytic durability and structural stability under industrial conditions is the key to practical alkaline anion exchange membrane (AEM) water electrolysis. Here, an energy-saving approach proposed synthesize defect-rich iron nickel oxyhydroxide for efficiency toward oxygen evolution reaction. Benefiting from in situ cation exchange, nanosheet-nanoflake-structured catalyst homogeneously embedded in, tightly bonded to, its substrate, making it...
Abstract Photodynamic therapy has been increasingly applied in clinical cancer treatments. However, native hypoxic tumoural microenvironment and lacking oxygen supply are the major barriers hindering photodynamic reactions. To solve this problem, we have developed biomimetic artificial red cells by loading complexes of oxygen-carrier (hemoglobin) photosensitizer (indocyanine green) for boosted strategy. Such nanosystem provides a coupling structure with stable self-oxygen acting as an ideal...
Multi-modal imaging-guided cancer photothermal therapy (PTT) with advanced theranostic nanoagents can efficiently improve therapeutic efficacy and reduce treatment side effects. Herein, we have developed a nanoagent based on indocyanine green (ICG)-loaded polydopamine (PDA)-iron ions coordination nanoparticles (PDA-Fe3+-ICG NPs), which are used for photoacoustic (PA) magnetic resonance (MR) dual-modal PTT treatments. In this nanoplatform, ICG molecules, the U.S. Food Drug Administration...
The richly functionalized basal plane bonded to polar organic moieties makes graphene oxide (GO) innately hydrophilic. Here, a methodology synthesize fluorinated by oxidizing the of graphite, allowing for tunable hydrophobicity GO, is reported. Fluorine exists as tertiary alkyl fluorides covalently graphitic carbons, and using magic‐angle spinning (MAS) 13 C NMR primary tool chemical structures two types synthesized oxides (FGOs) with significantly different fluorine contents are proposed....
The electrochemical conversion of carbon dioxide (CO2 ) to methane (CH4 ), which can be used not only as fuel but also a hydrogen carrier, has drawn great attention for use in supporting capture and utilization. design active selective electrocatalysts with exceptional CO2 -to-CH4 efficiency is highly desirable; however, it remains challenge. Here molecular tuning strategy-in situ amine functionalization nitrogen-doped graphene quantum dots (GQDs) efficient presented. Amine functionalized...
Abstract Renewable‐electricity‐powered carbon dioxide (CO 2 ) reduction (eCO R) to high‐value fuels like methane (CH 4 holds the potential close cycle at meaningful scales. However, this kinetically staggered 8‐electron multistep suffers from inadequate catalytic efficiency and current density. Atomic Cu‐structures can boost eCO R‐to‐CH selectivity due enhanced intermediate binding energies (BEs) resulting favorably shifted d‐band centers. In work, 2D nitride (CN) matrices, viz....
Metal–organic frameworks (MOFs) have been reported to catalyze the oxygen evolution reaction (OER). Despite established links between pristine MOFs and their derived metal hydroxide electrocatalysts, several limitations still preclude understanding of critical factors determining OER performance. Of prime importance appears choice MOF how its compositions relate catalyst stability in turn reconstruction or metamorphosis mechanisms into active species under conditions. An isoreticular series...
A new FRET model using near-infrared quantum-dots (NIR-QDs) and oxidized carbon nanoparticles (OCNPs) as the energy donor acceptor was constructed designed for insulin detection in complex human plasma.
Photodynamic therapy (PDT) has emerged as an effective treatment for tumor with minimal nonspecific damage to adjacent healthy tissues. Herein, redox-responsive self-quenching polysaccharide-based theranostic nanoparticles (DEX-SS-Ce6 NPs) were developed imaging and photodynamic therapy. The dextran–chlorin e6 conjugates (DEX-SS-Ce6) could self-assemble into uniform sphere shape in aqueous solution exhibit cellular "OFF/ON" behavior of a fluorescence signal. In addition, the DEX-SS-Ce6 NPs...
The precision oncology significantly relies on the development of multifunctional agents to integrate tumor targeting, imaging and therapeutics.In this study, a first small-molecule theranostic probe, RhoSSCy is constructed by conjugating 5′-carboxyrhodamines (Rho) heptamethine cyanine IR765 (Cy) using reducible disulfide linker pH tunable amino-group realize thiols/pH dual sensing.In vitro experiments verify that highly sensitive for quantitative analysis intracellular gradient...
Abstract The catalytic activity of palladium (Pd) nanostructures highly relies on their size and morphology, especially enclosed with high-index facets, which provide more active sites so as to enhance performance comparing low-index facet counterparts. Herein, Pd concave nanocubes {730} facets by a one-pot scalable liquid method, various are synthesized via tuning reduction kinetics. Due the exhibit much higher electrocatalytic stability for methanol oxidation than {100} commercial Pd/C....
Trimetallic Au/Ag/Pt hetero-nanostructures (AAPHNs) with distinctive, designed morphology are synthesized by galvanic replacement reaction and a site-selective strategy. The three metals present on the surface shown to act synergistically enhance electro-catalytic performance durability for methanol oxidation. described structural modification of nanocomposites increases range potential applications include both oxygen reduction in fuel cells photocatalysis hydrogen evolution reaction. As...
Indocyanine green (ICG) nanoparticles were developed via electrostatic interactions of ICG and dextran based block copolymers (PEG–dextran(–SS–NH2)) as near-infrared (NIR) theranostic nanoparticles. The could be activated from "OFF" to "ON" NIR fluorescence in an intracellular environment used for imaging photothermal therapy.