Fernanda Brito

ORCID: 0000-0002-5870-8576
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About
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Research Areas
  • Oral microbiology and periodontitis research
  • Atherosclerosis and Cardiovascular Diseases
  • Autoimmune and Inflammatory Disorders
  • Adipose Tissue and Metabolism
  • Inflammatory Bowel Disease
  • Cardiovascular Function and Risk Factors
  • Inflammatory mediators and NSAID effects
  • Diet and metabolism studies
  • Lipoproteins and Cardiovascular Health
  • Oral Health Pathology and Treatment
  • Chemical Synthesis and Analysis
  • Immunodeficiency and Autoimmune Disorders
  • COVID-19 Clinical Research Studies
  • Dental Health and Care Utilization
  • Oral and gingival health research
  • Diet, Metabolism, and Disease
  • Probiotics and Fermented Foods
  • Antioxidant Activity and Oxidative Stress
  • Adipokines, Inflammation, and Metabolic Diseases
  • Environmental Toxicology and Ecotoxicology
  • Birth, Development, and Health
  • Heart Rate Variability and Autonomic Control
  • Marine Biology and Environmental Chemistry
  • Synthesis and biological activity
  • Digestive system and related health

Universidade Federal Fluminense
2014-2024

Universidade Veiga de Almeida
2013-2021

Universidade do Estado do Rio de Janeiro
2006-2021

University Vascular Associates
2012-2013

Universidade Federal do Rio de Janeiro
2002-2004

The University of Texas at Austin
1997

To compare the prevalence of periodontal disease and decayed, missing filled teeth (DMFT) index in patients with Crohn's (CD) ulcerative colitis (UC) those without these diseases.Ninety-nine CD (39.0 SD+/-12.9 years), 80 UC (43.3 SD+/-13.2) 74 healthy controls (40.3 SD+/-12.9) were compared for DMFT presence periodontitis. Probing pocket depth (PPD), clinical attachment loss (CAL), bleeding on probing (BOP), plaque measured all subjects. The periodontitis was defined as having CAL > or =3 mm...

10.1111/j.1600-051x.2008.01231.x article EN Journal Of Clinical Periodontology 2008-04-09

Brito F, Almeida S, Figueredo CMS, Bregman R, Suassuna JHR, Fischer RG. Extent and severity of chronic periodontitis in kidney disease patients. J Periodont Res 2012; 47: 426–430. © 2011 John Wiley & Sons A/S Background Objectve: Chronic inflammatory diseases have been investigated as a possible source inflammation patients; however, there is shortage information about the prevalence such individuals. Therefore, aim this cross‐sectional study was to determine extent patients undergoing...

10.1111/j.1600-0765.2011.01449.x article EN Journal of Periodontal Research 2011-12-19

Objective To analyze the subgingival microflora composition of inflammatory bowel disease (IBD) patients with untreated chronic periodontitis and compare them systemically healthy controls also having periodontitis. Method Thirty IBD [15 Crohn's (CD) 15 ulcerative colitis (UC)] control individuals participated in study. All had been diagnosed From every patient, plaque was collected from four gingivitis sites paper points. Samples same category (gingivitis or periodontitis) each patient were...

10.1097/meg.0b013e32835a2b70 article EN European Journal of Gastroenterology & Hepatology 2012-10-11

Abstract This work presents a model of rats fed high‐cholesterol diet, receiving long‐term oral administration cilostazol, PDE 3‐inhibitor. The aim this study was to evaluate the molecular mechanisms by which cilostazol interferes with platelets signaling pathways avoid atherosclerosis early development. Male Wistar were divided into 3 groups: Control group received standard rat chow (C), hypercholesterolemic ( HCD ), and + CIL (cilostazol group) diet for 45 days. (30 mg/kg/p.o.) once daily...

10.1111/fcp.12195 article EN Fundamental and Clinical Pharmacology 2016-03-07

Previous studies have reported an increased prevalence/severity of chronic periodontitis in patients with inflammatory bowel disease. However, the pathogenesis periodontal lesions such has not been characterized. The aim this pilot study was to characterize pattern expression cytokines gingival crevicular fluid and serum from untreated Crohn's disease, ulcerative colitis systemically healthy controls.Fifteen 15 controls participated study. All subjects had diagnosed periodontitis. clinical...

10.1111/j.1600-0765.2010.01303.x article EN Journal of Periodontal Research 2010-08-05

Atherosclerosis is a multifactorial chronic disease, initiated by an endothelial dysfunction. Adenosine and its analogs can change variety of inflammatory diseases has shown important effects at different disease models. Inosine stable analogous adenosine, but in diseases, like atherosclerosis, have not yet been studied. The aim this study was to evaluate the pharmacological properties inosine, administered sub chronically hypercholesterolemic model. Male Wistar rats were divided into four...

10.1016/j.ejphar.2020.173289 article EN publisher-specific-oa European Journal of Pharmacology 2020-06-19

Background and Objective Our group recently found higher levels of serum l ong c hain– p olyunsaturated f atty a cids ( LC ‐ PUFA s) in patients with chronic periodontitis compared to controls. However, the effect periodontal treatment on has not been investigated. The primary aim present study was investigate impact levels. A secondary assess dietary ω‐3 supplementation clinical outcome. Material Methods test composed 10 generalized (mean age 44 ± 6.4 years) treated scaling root planing...

10.1111/jre.12104 article EN Journal of Periodontal Research 2013-05-31

Patients with juvenile idiopathic arthritis (JIA) can have alterations in bone metabolism and skeletal growth, as well damage to the temporomandibular joint (TMJ), which generate extra and/or intraoral alterations, resulting craniofacial disorders. Our goal is carry out a review of literature on orofacial patients JIA. Among disorders JIA, mandibular caused by dysfunctions TMJ region, seem highly prevalent these patients. The most often found are: retrognathia, micrognathia, anterior open...

10.1590/s0482-50042012000600009 article EN cc-by-nc-nd Revista Brasileira de Reumatologia 2012-12-01

Endothelial function is a key mechanism in the development of CVD. Arginine and exercise are important non-pharmacological strategies for mitigating impact metabolic changes syndrome, but effect their combined administration unknown. Thus, aim this study was to investigate isolated effects aerobic training arginine supplementation on variables vascular reactivity rats at high risk developing syndrome. Wistar were divided into two groups: control fructose (F - water with 10 % fructose). After...

10.1017/s0007114517001702 article EN British Journal Of Nutrition 2017-07-14

Introduction Cardiovascular diseases (CVD) are the main cause not only of global mortality but also reduced quality life. They cover ischemic heart disease, stroke, failure, peripheral artery and various other vascular conditions. In 2017, CVDs caused about 17.8 million deaths worldwide, corresponding to 330 years life lost another 35.6 with disabilities. Almost 80% occur in low- middle-income countries, such as Brazil, where occurrence [...]

10.36660/ijcs.20200081 article EN cc-by International Journal of Cardiovascular Sciences 2020-01-01

Cardiovascular disease is the major cause of death worldwide; therefore it important to understand natural history pathophysiologic process and develop strategies halt its progression. Thus this study investigated protective effect aerobic training on pathophysiological mechanisms involved in subclinical cardiometabolic alterations a model with constant exposure prejudicial agent. Male Wistar rats were divided into control group (C), which received drinking water, fructose (F), was fed 10%...

10.1152/japplphysiol.00369.2015 article EN Journal of Applied Physiology 2016-06-02

Periodontitis can corroborate with development and progression of atherosclerosis a possible bidirectional interaction between both pathologies has been hypothesized. The aim this work was to study the interactions diet-induced hypercholesterolemia ligature-induced periodontitis in Wistar rats submitted conditions.Animals were divided into four experimental groups: C (control: standard diet without periodontitis), Perio (periodontitis plus diet), HC (high cholesterol + periodontitis). diets...

10.1111/jre.12730 article EN Journal of Periodontal Research 2020-01-28
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