- Hydrogels: synthesis, properties, applications
- Silk-based biomaterials and applications
- Cellular Mechanics and Interactions
- Supramolecular Self-Assembly in Materials
- Voice and Speech Disorders
- Tracheal and airway disorders
- Advanced Battery Materials and Technologies
- Advanced Battery Technologies Research
- Electrospun Nanofibers in Biomedical Applications
- 3D Printing in Biomedical Research
- Drug Solubulity and Delivery Systems
- Dysphagia Assessment and Management
- Analytical Chemistry and Chromatography
- Cleft Lip and Palate Research
- Polymer Surface Interaction Studies
- Polydiacetylene-based materials and applications
- Polyoxometalates: Synthesis and Applications
- Crystallization and Solubility Studies
- Mesoporous Materials and Catalysis
- thermodynamics and calorimetric analyses
- Quantum Dots Synthesis And Properties
- Extraction and Separation Processes
Waters (United States)
2022-2023
University of Delaware
2014-2020
DuPont (United States)
2016-2020
Newark Hospital
2019
Drexel University
2014-2017
Philadelphia University
2014
Covalent co-assembly holds great promise for the fabrication of hydrogels with controllable nanostructure, versatile chemical composition, and enhanced mechanical properties given its relative simplicity, high efficiency, bond stability.
Abstract Heterogeneous hydrogels with desired matrix complexity are studied for a variety of biomimetic materials. Despite the range such microstructured materials described, few methods permit independent control over microstructure and microscale mechanics by precisely controlled, single‐step processing methods. Here, phototriggered crosslinking methodology that traps microstructures in liquid–liquid phase‐separated solutions highly elastomeric resilin‐like polypeptide (RLP) poly(ethylene...
Multiple approaches to generate microstructured hydrogels have emerged in order control microscale properties for applications ranging from mechanical reinforcement regenerative medicine. Here, we report new heterogeneous hybrid comprising emerging resilin-like polypeptides (RLPs); the can be engineered with controlled microstructure and distinct micromechanical via liquid–liquid phase separation (LLPS) of aqueous solutions RLPs poly(ethylene glycol) (PEG). The was captured by cross-linking...
Detailed understanding of the local structure–property relationships in soft biopolymeric hydrogels can be instrumental for applications regenerative tissue engineering.
Vocal folds are connective tissues housed in the larynx, which can be subjected to various injuries and traumatic stimuli that lead aberrant tissue structural alterations fibrotic-induced biomechanical stiffening observed patients with voice disorders. Much effort has been devoted generate soft biomaterials injectable directly sites of injury. To date, materials applied toward these applications have largely focused on natural extracellular matrix-derived such as collagen, fibrin or...
Abstract Local, micromechanical environment is known to influence cellular function in heterogeneous hydrogels, and knowledge gained micromechanics will facilitate the improved design of biomaterials for tissue regeneration. In this study, a system comprising microstructured resilin‐like polypeptide (RLP)–poly(ethylene glycol) (PEG) hydrogels utilized. The properties RLP‐PEG are evaluated with oscillatory shear rheometry, compression dynamic mechanic analysis, small‐strain microindentation,...
One-step formation of responsive “dumbbell” nanoparticle dimers<italic>via</italic>quasi-two-dimensional polymer single crystals.
Screening new cell chemistries using traditional electrochemical methods is a time prohibitive process that significantly slows the pace of research. These involve cycling until signs degradation or sufficient capacity fade are evident, and typically take months to complete. In-operando isothermal microcalorimetry an established but underutilized technique for measuring activity parasitic, non-reversible reactions during charge [1,2,3,4]. A parasitic reaction blanket term any side occur...
A lithium-ion battery’s performance characteristics demand the highest performing materials in anode, cathode, electrolyte, and separator. Materials characterization is an essential set of analytical techniques for ensuring optimal battery during stages material selection, development, manufacturing. Key technologies that batteries achieve their include thermal analysis, rheology, mechanical analysis isothermal microcalorimetry. Thermal provides insights into stability structure change under...