Delays in treating breast cancer have been associated with a more advanced stage of the disease and decrease patient survival rates. The scope this integrative review was to analyze main causal factors types system delays. underlying delays were compared among studies conducted developing developed countries. Of 53 selected, 24 carried out countries 29 countries, respectively. Non-attribution symptoms cancer, fear treatment low educational level most frequent causes delay. Less comprehensive...

Abstract Objectives: The aim of this study was to identify communities at high risk transmitting recessive genetic disorders by measuring levels endogamy and offspring's rate disabilities. Methods: In a house‐to‐house population based‐survey in the state Paraíba, 20,462 couples were interviewed regarding kinship relation, number siblings offspring affected mental or physical Results: consanguineous unions ranged from 6.0% 41.14%, showing an average value 20.19% ± 9.13%. overall inbreeding...

A new autosomal recessive genetic condition, the SPOAN syndrome (an acronym for spastic paraplegia, optic atrophy and neuropathy syndrome), was recently discovered in an isolated region of State Rio Grande do Norte Northeast Brazil, a population that identified by IBGE (Brazilian Institute Geography Statistics) as belonging to Brazilian communities with highest rates "deficiencies" (Neri, 2003), term used describe diseases, malformations, handicaps general. This prompted us conduct study...

The frequencies of molecular breast cancer subtypes vary among different human populations. Northeastern region Brazil has a mixed population African, Indigenous and European ancestry. This retrospective study investigated applied therapies in public hospital Brazil.Data 633 patients with invasive from 2005 to 2011 were obtained medical records. Status hormone receptor (HR), HER2 Ki67 expression index 269 out used define Luminal A B, triple negative (TN) cancer. Expression ≥ 14% was...

Background: In Brazil, little is known regarding the underlying causes of differences among populations regardingsocio-economic variables that affect women’s cervical cancer screening behavior. The present study focused onsocio-economic performance Papanicolaou test, comparing two distinct Brazilianpopulations. Methods: We collected data test and socio-economic variablesfrom 559 women in Mato Grosso do Sul (MS), Central East region, 338 Paraíba (PB), theNortheast region Brazil. Nominal...

The incidence and mortality rates of breast cancer in Northeast Brazil are increasing little is known about prevailing reproductive factors contributing to this increase. A case-control study was conducted a public hospital Campina Grande, state Paraiba, including 81 women with diagnosed invasive 162 age matched (±5 years) controls. Binominal logistic regression analysis applied estimate odds ratio (OR) confidence intervals (CI) risk factors. In model, at menarche≤12 (OR=2.120; CI:...

Breast cancer incidence and mortality rates are increasing in North-Eastern Brazil the patients with disease often presented at advanced stages. The present study was focused on identifying variables that affect women's frequency of breast self- examination (BSE) performance.Data BSE, socio-economic parameters risk factors for were obtained from 417 women a community by self-informant method. To identify independent nominal logistic regression analysis performed.Of women, 330 (79.3%)...

Objective: To evaluate the association between socioeconomic factors, health status, and Functional Capacity (FC) in oldest senior citizens a metropolis poor rural region of Brazil. Method: Cross-sectional study 417 seniors aged ≥80 years, data collected through Brazil’s Health, Well-being Aging survey. FC assessed by self-reporting difficulties Activities Daily Living (ADLs) Instrumental (IADLs). Chi-square tests multiple logistic regression analyses were performed using “R” statistical...

Background: A longer lifespan and changing lifestyle-related reproductive risk factors have led to an increased incidence of breast cancer in Brazil. There been few studies about associations specific with molecular subtypes the disease. The aim present study was identify that modulate triple negative cancer. Materials Methods: case-case analysis performed. Data for 236 patients from two reference centres North-eastern Brazil were applied assess association relative luminal subtype....

Despite conceptual inaccuracies and methods of measurement, the WHO estimates that about 10% world population has some form disability. In order to investigate prevalence etiology disabilities evaluate if they could be associated with inbreeding, a cross-sectional epidemiological study was conducted using informant method in five communities state Rio Grande do Norte Brazilian Northeast, which consanguineous marriages frequencies varied between 9 32%. The average sampled 4.53%, obtained by...

The incidence and mortality rates of colorectal cancer (CRC) in Northeast Brazil are increasing. To study the association between CRC diet, data were obtained from 64 patients with 123 sex- age-matched controls. dietary details recorded using a validated food frequency questionnaire. Nutrient intake was calculated Dietsys software (National Cancer Institute, Maryland, USA). In binary logistic regression model components (model 1), chance increased by 0.2% (odds ratio [OR] = 1.002; 95%...

Background: Consanguinity of human populations can but does not have to be associated with increased fertility. A recent study involving communities Northeast Brazil revealed levels endogamy.

The present study aimed at analyzing the genetic variability of indigenous goat breeds (Capra hircus) using MHCassociated microsatellite markers BF1, BM1818, BM1258, DYMS1, and SMHCC1.The following were included: Chinese Xuhuai, Indian Changthangi Pashmina, Kenyan Small East African (SEA) Galla, Albanian Vendi.To examine variability, levels heterozigosity, degrees inbreeding, differences among analyzed.The mean number alleles ranged from nine in Galla to 14.5 Vendi breed.The observed...

Background: Previous Brazilian studies have indicated that working in agriculture could lead to an increased risk of penile cancer. The present descriptive study aimed at establishing a possible association between cancer and agricultural occupation. Materials methods: Data on total 103 patients were obtained from medical records two reference centres for treatment the state Paraíba, Northeast Brazil. Information about sexual behaviour was interviews 48 cases. Results: Of 38 52 illiterate...

This paper deals with the frequency and structure of first-cousin marriages, by far most important frequent type consanguineous mating in human populations. Based on analysis large amounts data from world literature Brazilian samples recently collected, we suggest some explanations for asymmetry sexes among parental sibs marriages. We also a simple manner to correct method that uses population surnames assess different Wright fixation indexes FIS, FST FIT taking into account not only...

Os remanescentes das espécies de equídeos do Nordeste brasileiro dizem respeito principalmente àquelas populaçõeslocais cavalos, jumentos e burros; que estão adaptadas desenvolveram papel fundamental na formação econômica, social histórica da região. Devido a sua rusticidade resistência ao ambiente pouco favorável Semiárido são utilizados no transporte, sela, carga tração. Estima-se existam cerca 570 raças locais mundo. O Brasil possui terceira maior população mundo, com destaque para o...

Knowledge about risk factors for breast cancer was identified as an important variable that affects women's avoidance behavior and their screening performance. The present study assessed knowledge associated socio-economic variables. Data from 417 women aged 20–86 years were obtained in Caicó, Rio Grande do Norte, Brazil. In agreement with the recognition of 26 potential prevention behaviors, two groups good (N = 203) poor 214) formed, respectively. Having a close relative remained unique...

Background: Previous studies suggest that education and income affect Brazilian women's breast cancer prevention behavior. The present study focused on the impact of perceived estimated risk mammography screening (MS) Materials Methods: Information regarding socioeconomic variables perception was obtained from 396 healthy women aged 40–79 years. Perceived comparative measured a seven-point Likert scale. A Breast Cancer Risk Assessment Tool 5-year to develop used determine objective risk....

Background: System delay (SD) is a leading cause of advanced stage disease and poor prognosis among Brazilian breast cancer patients. Methods: Cox regression Kaplan-Meier analysis were used to identify variables that contributed SD 128 Time intervals between first medical consultation treatment initiation compared patients two referral centres: Patients centre with outsourced (FAP), respectively, integrated (HNL) diagnostic services. Results: Women who specialized private clinic at the...

Fish trypanosomes have traditionally been classified according to the host species from which they were isolated, each isolate being regarded as a distinct species. To test soundness of this practice, genetic variabilities kinetoplast 12S rRNA-encoding genes different fish isolates compared. The DNAs extracted cloned blood samples 15 donors representing ten in four orders waters three major river systems Central and Northern Europe. Comparison with other trypanosomatid sequences revealed...