A5072485765- Functional Brain Connectivity Studies
- Mental Health Research Topics
- Advanced MRI Techniques and Applications
- Pain Management and Placebo Effect
- Face Recognition and Perception
- Advanced Neuroimaging Techniques and Applications
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Transcranial Magnetic Stimulation Studies
- Treatment of Major Depression
- Pain Mechanisms and Treatments
- Attention Deficit Hyperactivity Disorder
- Neurological disorders and treatments
- Musculoskeletal pain and rehabilitation
- Seismology and Earthquake Studies
Medical University of Vienna
2016-2021
TU Wien
2017
Abstract Several previous functional magnetic resonance imaging (fMRI) studies have demonstrated the predictive value of brain activity during emotion processing for antidepressant response, with a focus on clinical outcome after 6–8 weeks. However, longitudinal emphasize paramount importance early symptom improvement course disease in major depressive disorder (MDD). We therefore aimed to assess whether neural discrimination task (EDT) predicts effects, and how these measures relate more...
Despite its importance as the prime method for non-invasive assessment of human brain function, functional MRI (fMRI) was repeatedly challenged with regards to validity fMRI-derived activation maps. Amygdala fMRI particularly targeted, amygdala's anatomical position in ventral combined strong magnetic field inhomogeneities and proximity large vessels pose considerable obstacles robust mapping. In this high-resolution study performed at ultra-high (7T) fMRI, we aimed (1) investigating...
Functional magnetic resonance imaging (fMRI) successfully disentangled neuronal pathophysiology of major depression (MD), but only a few fMRI studies have investigated correlates and predictors remission. Moreover, most used clinical outcome parameters from two time points, which do not optimally depict differential response times. Therefore, we aimed to detect remission in an antidepressant treatment study with 7 T fMRI, potentially harnessing advances detection power spatial specificity....
Increased amygdala activation is consistently found in patients suffering from social anxiety disorder (SAD), a psychiatric condition characterized by an intense fear of situations and scrutiny. Disruptions the amygdalar-frontal network SAD may explain inability frontal regions to appropriately down-regulate amygdalar hyper-activation. In this study, we measured 15 healthy controls during affective counting Stroop task with emotional faces assess interaction stimuli cognitive SAD, as well...
Introduction: The importance of the amygdala/medial orbitofrontal cortex (OFC) network during processing emotional stimuli, faces in particular, is well established. This premise supported by converging evidence from animal models, human neuroanatomical results, and neuroimaging studies. However, there missing brain connectivity studies that OFC no other prefrontal areas such as dorsolateral (DLPFC) or ventrolateral (VLPFC) are responsible for amygdala regulation functional context face...
Pain habituation is associated with a decrease of activation in brain areas related to pain perception. However, little known about the specificity these decreases pain, as has also been described for other responses like spinal reflexes and sensory responses. Thus, it might be hypothesized that previously reported reductions are not specifically habituation. For this reason, we performed 3 T fMRI study using either painful or non-painful electrical stimulation via an electrode attached back...
associations for proteins involved in cell regulation 1 .Strong correlations were found the serotonin-1A receptor as well monoamine oxidase-A (MAO-A) 2,3 .However, regulatory processes induced via exogenous and endogenous substrates have been described MAO-A, leading to an altered enzyme activity smokers or depressive patients 4,5 .To assess potential influences of post-transcriptional modifications MAO-A between imaging data gene expression performed.Methods: PET total volume distribution...
67%±13%). Functional MRI revealed decreased activation in the right inferior frontal (rIFC, p FWE-cluster =0.02) and left middle temporal gyri (lMTG, =0.03) to negative faces following citalopram infusion (for p=0.001 uncorrected on peak level). Conclusions:The newly implemented methods yielded serotonin transporter occupancy values agreement with published data obtained using well validated procedures [1].FMRI results are at odds increased activity during an emotional paradigm lMTG 10 days...
When analyzing data from functional magnetic resonance imaging, different mathematical models are used.This article briefly describes the most important ones -starting with so-called balloon model describing hemodynamic response during brain activity, General Linear Model widely used for localization of areas involved certain stimuli, and Dynamic Causal Modelling as a framework investigating dynamic connectivity models.
Abstract Pain habituation is associated with a decrease of activation in brain areas related to pain perception. However, little known about the specificity these decreases pain, as has also been described for other responses like spinal reflexes and sensory responses. Thus, it might be hypothesized that previously reported reductions are not specifically habituation. For this reason, we performed 3T fMRI study using either painful or non-painful electrical stimulation via an electrode...