A5052980150- Functional Brain Connectivity Studies
- Advanced MRI Techniques and Applications
- Transcranial Magnetic Stimulation Studies
- Advanced Neuroimaging Techniques and Applications
- Neurological disorders and treatments
- Mental Health Research Topics
- Neural dynamics and brain function
- Visual perception and processing mechanisms
- Retinal Development and Disorders
- Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Atomic and Subatomic Physics Research
- Medical Imaging Techniques and Applications
- Psychosomatic Disorders and Their Treatments
- Optical Imaging and Spectroscopy Techniques
- Treatment of Major Depression
- Photoacoustic and Ultrasonic Imaging
- Advanced NMR Techniques and Applications
- Ultrasound Imaging and Elastography
- Spaceflight effects on biology
- EEG and Brain-Computer Interfaces
- Empathy and Medical Education
- Retinal Imaging and Analysis
- Retinal Diseases and Treatments
- Cerebrovascular and Carotid Artery Diseases
- Gaze Tracking and Assistive Technology
Medical University of Vienna
2016-2025
Transcranial magnetic stimulation (TMS) applied to a left dorsolateral prefrontal cortex (DLPFC) area with specific connectivity profile the subgenual anterior cingulate (sgACC) has emerged as highly effective non-invasive treatment option for depression. However, antidepressant outcomes demonstrate significant variability among therapy plans and individuals. One overlooked contributing factor is individual brain state at time of treatment. In this study we used interleaved TMS-fMRI...
Abstract Several previous functional magnetic resonance imaging (fMRI) studies have demonstrated the predictive value of brain activity during emotion processing for antidepressant response, with a focus on clinical outcome after 6–8 weeks. However, longitudinal emphasize paramount importance early symptom improvement course disease in major depressive disorder (MDD). We therefore aimed to assess whether neural discrimination task (EDT) predicts effects, and how these measures relate more...
Transcranial magnetic stimulation (TMS) is an FDA-approved therapeutic option for treatment resistant depression. However, exact mechanisms-of-action are not fully understood and individual responses variable. Moreover, although previously suggested, the network effects underlying TMS' efficacy poorly as of today. Although, it supposed that DLPFC indirectly modulates sgACC, recent evidence sparse.
TMS is a valuable tool in both research and clinical settings, playing crucial role understanding brain-behavior relationships providing treatment for various neurological psychiatric conditions. Importantly, over left DLPFC an FDA approved MDD. Despite its potential, response variability to remains challenge, with stimulation parameters, particularly the intensity, being primary contributor these differences.The objective of this study was establish dose-response by means concurrent...
Abstract Magnetic resonance imaging (MRI) has become the prime technique for in vivo examination of brain. In addition to anatomical and functional MRI, diffusion MRI (dMRI) is widely used both clinics research assess tissue structure fiber directions, particularly nervous system. While tensor most widespread approach assessing orientation measures, other, more sophisticated models have also been proposed. Validation dMRI is, however, a challenging endeavor that requires specialized test...
Purpose To overcome current limitations in combined transcranial magnetic stimulation (TMS) and functional resonance imaging (fMRI) studies by employing a dedicated coil array design for 3 Tesla. Methods The state‐of‐the‐art setup concurrent TMS/fMRI is to use large birdcage head coil, with the TMS between subject's MR coil. This has drawbacks sensitivity, positioning, available techniques. In this study, an ultraslim 7‐channel receive‐only T, which can be placed TMS, presented. Interactions...
Despite its importance as the prime method for non-invasive assessment of human brain function, functional MRI (fMRI) was repeatedly challenged with regards to validity fMRI-derived activation maps. Amygdala fMRI particularly targeted, amygdala's anatomical position in ventral combined strong magnetic field inhomogeneities and proximity large vessels pose considerable obstacles robust mapping. In this high-resolution study performed at ultra-high (7T) fMRI, we aimed (1) investigating...
ABSTRACT Population receptive field (pRF) mapping is a quantitative functional MRI (fMRI) analysis method that links visual positions with specific locations in the cortex. A common preprocessing step pRF analyses involves projecting volumetric fMRI data onto cortical surface, typically leading to upsampling of data. This process may introduce biases resulting parameters. Using publicly available containers, we compared maps generated from original those upsampled surface Our results show...
"Wernicke's area" is most often used to describe the posterior superior temporal gyrus (STG) and refers a region traditionally thought support language comprehension. However, STG additionally plays critical role in production. The purpose of current study was determine what extent regions within are selectively recruited during production.23 healthy right-handed participants completed an auditory fMRI localizer task, resting-state underwent neuronavigated TMS mapping. We applied repetitive...
Functional magnetic resonance imaging (fMRI) successfully disentangled neuronal pathophysiology of major depression (MD), but only a few fMRI studies have investigated correlates and predictors remission. Moreover, most used clinical outcome parameters from two time points, which do not optimally depict differential response times. Therefore, we aimed to detect remission in an antidepressant treatment study with 7 T fMRI, potentially harnessing advances detection power spatial specificity....
Abstract Major depressive disorder (MDD) has been hypothesized to lead impairments in empathy. Previous cross-sectional studies did not disentangle effects of MDD itself and antidepressant treatment. In this first longitudinal neuroimaging study on empathy depression, 29 patients with participated two functional magnetic resonance imaging (fMRI) sessions before after 3 months therapy. We compared their responses an for pain task a group healthy controls ( N = 35). All participants provided...
Abstract Background Studies investigating hippocampal volume changes after treatment with serotonergic antidepressants in patients major depressive disorder yielded inconsistent results, and effects on subfields are unclear. Methods To detail total subfield volumes, we conducted an open-label study escitalopram followed by venlafaxine upon nonresponse 20 unmedicated disorder. Before 12 weeks treatment, measured formation volumes ultra-high field (7 Tesla), T1-weighted, structural magnetic...