A5079148287- Enzyme Production and Characterization
- Enzyme Catalysis and Immobilization
- Electrochemical sensors and biosensors
- Enzyme Structure and Function
- Enzyme-mediated dye degradation
- Advanced biosensing and bioanalysis techniques
- Proteoglycans and glycosaminoglycans research
- Biofuel production and bioconversion
- Protein Interaction Studies and Fluorescence Analysis
- Protein Structure and Dynamics
- Phytase and its Applications
- Protein Hydrolysis and Bioactive Peptides
- Microbial Metabolic Engineering and Bioproduction
- Protease and Inhibitor Mechanisms
- Biotin and Related Studies
- bioluminescence and chemiluminescence research
- Nanoparticle-Based Drug Delivery
- Alzheimer's disease research and treatments
- Microbial Metabolism and Applications
- Peptidase Inhibition and Analysis
- Nerve injury and regeneration
- Photoreceptor and optogenetics research
- Glycosylation and Glycoproteins Research
- Analytical chemistry methods development
- RNA Interference and Gene Delivery
Tarbiat Modares University
2016-2025
Macquarie University
2023
University of Tehran
2000-2016
Azarbaijan Shahid Madani University
2012
Shahid Beheshti University
2012
University of Guilan
2010
Shiraz University
2010
Sharif University of Technology
2007
Razi University
2007
Kermanshah University of Medical Sciences
2007
Abstract Fifty strains of moderately halophilic bacteria were isolated from various salty environments in Iran. A strain designated as SA‐2 was shown to be the best producer extracellular lipase and selected for further studies. Biochemical physiological characterization along with 16S rDNA sequence analysis placed genus Salinivibrio . The optimum salt, pH, temperature aeration enzyme production 0.1 M KCl, pH 8, 35 °C 150 rpm, respectively. synchronized bacterial growth reached a maximum...
This work reports a novel nanobiosensor based on thioglycolic acid (TGA)-capped CdTe quantum dot-laccase (Lac) enzyme system for sensitive detection of dopamine (DA). The used catalyzes the oxidation DA to dopamine-o-quinone (DOQ), which can selectively quench strong luminescence nanocrystals at neutral pH. relationship between intensity and concentration is nicely described by Stern-Volmer equation. At an optimum pH 7.4, proposed sensor gives linear calibration over range 0.3 100 μM, with...
In our previous study, we reported an increase in the thermal stability of bacterial laccase from Bacillus sp. HR03 using site‐directed mutagenesis. Three‐dimensional model this enzyme showed a negative patch connecting loop between domains 1 and 2. present organic solvents was improved by introducing nonpolar (E188 → A, I, L, V) positively charged K R) residues region Irreversible thermoinactivation, C 50 value (organic solvent concentration at which 50% activity remains), change...
Tumor blood vessels have been reported to be abnormal in both structure and function compared with those normal tissues, leading a hostile microenvironment inadequate antitumor drug delivery. Dopamine, chemical messenger, is proven inhibit angiogenesis improve tumor vessel normalization. Here, mesoporous silicon nanoparticle (MSN) constructed that responsive the weakly acidic pH of extracellular matrix for steady delivery tumor‐localized release dopamine. Then MSNs are functionalized amine...
Dopamine is one of the significant neurotransmitters and its monitoring in biological fluids a critical issue healthcare modern biomedical technology. Here, we have developed dopamine biosensor based on surface plasmon resonance (SPR). For this purpose, carboxymethyl dextran SPR chip was used as to immobilize laccase bioaffinity recognition element. Data analysis exhibited that acidic pH value optimal condition for interaction. Calculated kinetic affinity (K
Ossicular chain reconstruction (OCR) is the gold standard for repairing conductive hearing loss (CHL) using prosthetic devices. However, few techniques can validate prosthesis performance before translational implementation. This study not only validates a Finite Element (FE) model examining (reconstructed) middle ear biomechanics, but also evaluates potential of personalised devices OCR. Additionally, this research examines tricalcium phosphate (TCP), as biomaterial, besides titanium and...