A. Benslimane

ORCID: 0000-0002-5923-4843
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About
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Research Areas
  • Nutritional Studies and Diet
  • Diabetes, Cardiovascular Risks, and Lipoproteins
  • Tuberculosis Research and Epidemiology
  • Venomous Animal Envenomation and Studies
  • Diagnosis and treatment of tuberculosis
  • Chronic Obstructive Pulmonary Disease (COPD) Research
  • Colorectal Cancer Screening and Detection
  • Mycobacterium research and diagnosis
  • Ion channel regulation and function
  • Nutrition, Genetics, and Disease
  • Consumer Attitudes and Food Labeling
  • Hepatitis C virus research
  • Liver Disease Diagnosis and Treatment
  • Diabetes Management and Education
  • Delphi Technique in Research
  • Blood groups and transfusion
  • Parvovirus B19 Infection Studies
  • School Health and Nursing Education
  • Cancer, Lipids, and Metabolism
  • Nutrition and Health in Aging
  • Genomic variations and chromosomal abnormalities
  • Hepatitis B Virus Studies
  • Immunodeficiency and Autoimmune Disorders
  • Reproductive tract infections research
  • Respiratory viral infections research

Sidi Mohamed Ben Abdellah University
2018-2025

Instituts Supérieurs des Professions Infirmières et Techniques de Santé
2025

Agence pour le Développement et la Réhabilitation de la Ville de Fès
2019

Departamento de Epidemiología
2009-2018

Pharmac
2012

University of Hassan II Casablanca
1987-2011

Institut Pasteur
1993-2000

Institut Pasteur du Maroc
1991-1997

Centre Hospitalier Universitaire Ibn Rochd
1996-1997

Centre de Recherche en Neurobiologie - Neurophysiologie de Marseille
1992

A peptidyl inhibitor of the high conductance Ca(2+)-activated K+ channels (KCa) has been purified to homogeneity from venom scorpion Androctonus mauretanicus mauretanicus. The peptide named kaliotoxin (KTX). It is a single 4-kDa polypeptide chain. Its complete amino acid sequence determined. KTX displays homology with other scorpion-derived inhibitors or voltage-gated channels: 44% charybdotoxin (CTX), 52% noxiustoxin (NTX), and iberiotoxin (IbTX). Electrophysiological experiments performed...

10.1016/s0021-9258(18)45993-5 article EN cc-by Journal of Biological Chemistry 1992-01-01

To date, no culture-specific food frequency questionnaires (FFQ) are available in North Africa. The aim of this study was to adapt and examine the reproducibility validity an FFQ or use Moroccan population. European Global Asthma Allergy Network (GA2LEN) used assess its applicability Morocco. GA2LEN is comprised 32 sections 200 items. Using scientific published literature, as well local resources, we identified added foods that were representative diet. Translation into Arabic carried out...

10.1186/s12937-018-0368-4 article EN cc-by Nutrition Journal 2018-06-12

A clinical and biologic study was conducted in Morocco to assess the efficiency of antivenom therapy for treating victims scorpion stings. Epidemiologic data were collected from 275 patients envenomed by Androctonus mauretanicus Buthus occitanus scorpions. Patients received or other drugs. Blood samples at time hospital admission 1 hr 3 after treatment. Serum venom levels quantified using an ELISA. An association found between signs envenoming level serum. classified as grade II (moderate...

10.4269/ajtmh.2000.62.277 article EN American Journal of Tropical Medicine and Hygiene 2000-02-01

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTP05, a new leiurotoxin I-like scorpion toxin: Synthesis and structure-activity relationships of the .alpha.-amidated analog, ligand calcium-activated potassium channels with increased affinityJ. M. Sabatier, H. Zerrouk, Darbon, K. Mabrouk, A. Benslimane, Rochat, F. Martin-Eauclaire, J. Van RietschotenCite this: Biochemistry 1993, 32, 11, 2763–2770Publication Date (Print):March 23, 1993Publication History Published online1 May 2002Published inissue...

10.1021/bi00062a005 article EN Biochemistry 1993-03-23

Abstract Objective: The Mediterranean diet (MD) is a dietary pattern associated with several health benefits, including reduction of risk for various cancers. We conducted study to investigate associations between adherence the MD and colorectal cancer (CRC) subtype among Moroccan adults. Design: A matched case-control study. Setting: five major university hospitals in Morocco. Participants: total 3032 subjects (1516 CRC patients 1516 controls) on age, sex center, were recruited September...

10.1017/s1368980025000199 article EN cc-by-nc-nd Public Health Nutrition 2025-02-06

Background: Coronavirus disease 2019 (COVID‐19) has emerged as a global human health threat. While SARS‐CoV‐2 infection exhibits fever and respiratory symptoms, extrarespiratory manifestations were also reported in many cases. Objectives: This study aimed to determine the prevalence of digestive hepatic symptoms at onset assess whether are associated with severe progression. Patients Methods: Prospective was conducted during first COVID‐19 wave (from April October 2020). It included...

10.1155/sci5/3524776 article EN cc-by Scientifica 2025-01-01

Three novel peptide inhibitors of the SKCa channels were purified to homogeneity from venom scorpion Androctonus mauretanicus using one step RP-HPLC and competition assays with [125I]apamin rat brain synaptosomes. PO1, PO2 PO5 have K0.5 100, 100 0.02 nM, respectively, for apamin binding site. The sequence was established compared that other toxins active on K+ channels: it contains 31 residues has a free carboxyl end. shares similarity leiurotoxin I.

10.1016/0014-5793(93)80583-g article EN FEBS Letters 1993-04-12

The current study aimed to investigate the relationship between red and white meat subtypes, processed (divided into traditional "Khlii, Kaddid" industrially meat) colorectal cancer (CRC) risk, considering CRC subsites, in Moroccan adults. A case-control was conducted including 2,906 matched pairs recruited from five largest university hospitals Morocco. Dietary data were collected through a validated Food Frequency Questionnaire (FFQ). Multivariable odds ratios (OR) 95% confidence intervals...

10.1002/ijc.32689 article EN International Journal of Cancer 2019-09-16

The present study aimed to investigate associations between adherence the recommendations on cancer prevention from WCRF/AICR and colorectal (CRC) risk in Morocco. Incident CRC cases (n = 1,516) controls matched age, sex center, were recruited September 2009 February 2017 at five major hospitals located In-person interviews conducted assess habitual diet using a validated Food Frequency Questionnaire, physical activity anthropometric measurements. Adherence WCRF/AIRC Recommendations was...

10.1002/ijc.32263 article EN International Journal of Cancer 2019-03-12

Serological tests based on the antibodies directed against Epstein-Barr virus early antigen (EA) and viral capsid (VCA), which have been recognized as tumor markers for nasopharyngeal carcinoma (NPC), are routinely used to help in diagnosis of this malignancy. The detection these reveals very low titers, found only a small proportion young compared with older NPC patients. This is problem NPC, especially among Maghrebians, whom people also affected, emphasizes necessity search more reliable...

10.1128/jcm.39.9.3164-3170.2001 article EN Journal of Clinical Microbiology 2001-09-01

Background Colorectal cancer (CRC) has been reported as the third most commonly diagnosed worldwide and is currently considered a major public health concern. A peak increase in incidence noted economically transitioning countries like Morocco where industrialization started shifting from traditional lifestyle diet toward more westernized lifestyle. Objective This paper aims to present protocol of large-scale Moroccan case-control study that at investigating associations diet, other factors,...

10.2196/13998 article EN cc-by JMIR Research Protocols 2019-07-19

Abstract Objectives: The current study aimed to develop a modified Mediterranean diet (MMD) score adjusted the southern countries’ cultural specificities and evaluate associations between adherence this overweight/obesity risk in Moroccan adults. Design: Population-based cross-sectional study. Setting: Rural urban areas of five greatest provinces Morocco. Participants: In total, 1516 participants were recruited September 2009 February 2017. Dietary assessment was obtained using validated...

10.1017/s1368980020002062 article EN Public Health Nutrition 2020-07-29

The Moroccan cross-sectional study aimed to investigate obesity in association chronic obstructive pulmonary disease Fez city.A survey was carried out adults. Anthropometric and spirometry measurements were performed using standardized guidelines.Among the 744 participants, 53.9% of women, with a mean age 55.27 years (SD = 10.29). Nearly all women declared themselves be never smokers, while 21% men current smokers. Overall, prevalence decreased body mass index (p 0.01) waist circumference <...

10.1177/20503121211031428 article EN cc-by-nc SAGE Open Medicine 2021-01-01
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