A5001172041- Global Cancer Incidence and Screening
- Colorectal Cancer Screening and Detection
- Cervical Cancer and HPV Research
- Cancer Risks and Factors
- Breast Cancer Treatment Studies
- Cancer Genomics and Diagnostics
- Pancreatic and Hepatic Oncology Research
- Advances in Oncology and Radiotherapy
- Hepatitis B Virus Studies
- Genetic factors in colorectal cancer
- Carcinogens and Genotoxicity Assessment
- Vaccine Coverage and Hesitancy
- AI in cancer detection
- Liver Disease Diagnosis and Treatment
- Endometrial and Cervical Cancer Treatments
- Viral-associated cancers and disorders
- Genital Health and Disease
- Hepatitis C virus research
- BRCA gene mutations in cancer
- Economic and Financial Impacts of Cancer
- Epigenetics and DNA Methylation
- Effects and risks of endocrine disrupting chemicals
- Colorectal Cancer Treatments and Studies
- Cancer-related molecular mechanisms research
- Cancer Immunotherapy and Biomarkers
City University of New York
2018-2025
City College of New York
2021-2025
The Ohio State University
2024
King Khalid University
2024
New York Medical College
2019-2024
Mansoura University
2024
International Islamic University Malaysia
2024
University of Technology Malaysia
2024
Nahda University
2024
Pius Hospital Oldenburg
2022
To describe urban-rural differences in breast cancer incidence Gharbiah, Egypt and to investigate if these could be explained by known risk factors of cancer.We used data from the population-based registry assess 1999 through 2006. The Egyptian census provided on district-specific population, age, classification. Incidence patterns district age-specific were analyzed.Overall, rate was three four times higher urban areas than rural (60.9/10(5)-year for versus 17.8/10(5)-year areas; IRR=3.73,...
Background: The frequency rates of mutations such as KRAS, NRAS, BRAF, and PIK3CA in colorectal cancer (CRC) differ among populations. aim this study was to assess mutation frequencies the Arab population determine their correlations with certain clinicopathological features. Methods: patients from Gulf region a age- sex-matched Western CRC whose tumors were evaluated next-generation sequencing (NGS) identified retrospectively reviewed. PIK3CA, TP53, APC recorded, along Other somatic also...
The northeast Nile Delta region exhibits a high incidence of early-onset pancreatic cancer. It is well documented that this has one the highest levels pollution in Egypt. Epidemiologic studies have suggested cadmium, prevalent pollutant region, plays role development cancer.Objective: We aimed to assess serum cadmium as markers exposure cancer patients and noncancer comparison subjects from same Egypt.Design Participants: assessed 31 newly diagnosed 52 hospital Mansoura,...
This study examined the epidemiology of pancreatic cancer in Egypt.We obtained detailed information on smoking, occupational, medical, and reproductive histories from 194 cases controls.Compared with not smoking cigarettes alone or conjunction other methods (eg, water pipe, cigar) was associated an increased risk (odds ratio [OR], 4.5 7.8; 95% confidence interval [95% CI], 1.9-10.7 3.0-20.6, respectively). Passive also a significant factor (OR, 6.0; CI, 2.4-14.8). The elevated among subjects...
PURPOSE: Lifestyle factors and environmental exposures might help explain the risk of colorectal carcinoma in countries where incidence is low, but unique patterns young onset a high proportion rectal cancer exist. METHODS: We obtained detailed lifestyle information from 421 patients with 439 hospital-controls Egypt. Logistic regression models were computed to evaluate carcinoma. RESULTS: A history pesticide exposure more frequently eating food directly farms significantly associated higher...
Purpose: Breast cancer is a highly heterogeneous disease globally. Public health prevention measures require an understanding of the burden breast and its risk factors. The purpose this study was to describe clinical, pathologic,
HIV substantially worsens human papillomavirus (HPV) carcinogenicity and contributes to an important population excess of cervical cancer, particularly in sub-Saharan Africa (SSA). We estimated HIV- age-stratified cancer burden at a country, regional global level 2020. Proportions (a) diagnosed women living with (WLHIV), (b) attributable HIV, were calculated using age-specific estimates prevalence (UNAIDS) relative risk. These proportions validated against empirical data applied incidence...
Colorectal carcinoma is uncommon in Egypt, but a high proportion of cases occurs before age 40 years and the rectum. We compared molecular pathology 59 representative Egyptian patients aged 10–72 to Western with sporadic, young-onset, or hereditary non-polyposis colorectal cancer syndrome (HNPCC)-associated found significant differences. Most cancers were rectal (51%) poorly differentiated (58%). High levels microsatellite instability (MSI-H) frequent (37%) attributable some (36%)...
Estrogen receptor (ER) status is an important biomarker in defining subtypes of breast cancer differing antihormonal therapy response, risk factors and prognosis. However, little known about association ER with various the developing world. Our case-control study done Kerala, India looked at associations cancer. From 2002 to 2005, 1,208 cases controls were selected Regional Cancer Center (RCC), Trivandrum, India. Information was collected using a standardized questionnaire, 3-way analyses...
Cervical screening for carcinogenic human papillomavirus (HPV) infection is being considered low-income countries. Effectiveness requires targeted in older women whom prevalent infections are more likely to be persistent and predictive of precancer. Some studies West Africa have found unusually high HPV prevalences across all adult ages, which may reduce the positive value (PPV) HPV-based screening, if positivity does not sufficiently predict elevated risk. We conducted a population-based...
The long-term effect of socioeconomic status (SES) and healthcare resources availability (HCA) on breast cancer stage presentation mortality rates among patients in Michigan is unclear. Using data from the Department Community Health (MDCH) between 1992 2009, we calculated annual proportions late-stage diagnosis age-adjusted by race zip code Michigan. SES HCA were defined at zip-code level. Joinpoint regression was used to compare Average Annual Percent Change (AAPC) median level percent...
Abstract Background Exposure to endocrine active compounds, including bisphenol A (BPA), remains poorly characterized in developing countries despite the fact that behavioral practices related westernization have potential influence exposure. BPA is a high production volume chemical has been associated with metabolic dysfunction as well and developmental effects people, children. In this pilot study, we evaluate exposure assess likely pathways of among girls from urban rural Egypt. Methods...
Morocco's national breast cancer screening program (NBCSP) was launched in 2010 response to rising incidence. The comprises clinical examination (CBE) and diagnostic mammography aims improve early diagnosis management. This study evaluated key performance indicators of the NBCSP for Casablanca-Settat region from 2018 2021. Aggregated regional data on activities under were extracted a health information system. Annual coverage, participation, CBE-positivity, detection rates then calculated....
Colorectal carcinoma is uncommon in Egypt, but a high proportion of cases occurs before age 40 years and the rectum. We compared molecular pathology 59 representative Egyptian patients aged 10–72 to Western with sporadic, young-onset, or hereditary non-polyposis colorectal cancer syndrome (HNPCC)-associated found significant differences. Most cancers were rectal (51%) poorly differentiated (58%). High levels microsatellite instability (MSI-H) frequent (37%) attributable some (36%)...