A5052702985- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Neurological Disorders and Treatments
- Neurological Disease Mechanisms and Treatments
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiovascular Health and Disease Prevention
- Cerebrovascular and genetic disorders
- Mental Health and Psychiatry
- Neurosurgical Procedures and Complications
- Medical Imaging Techniques and Applications
- Spinal Fractures and Fixation Techniques
- Neurology and Historical Studies
- Medical Imaging and Analysis
- Antiplatelet Therapy and Cardiovascular Diseases
- Glioma Diagnosis and Treatment
- Venous Thromboembolism Diagnosis and Management
- Advanced MRI Techniques and Applications
- Historical Psychiatry and Medical Practices
- Spine and Intervertebral Disc Pathology
- Toxoplasma gondii Research Studies
- Stroke Rehabilitation and Recovery
- Fetal and Pediatric Neurological Disorders
- Psoriasis: Treatment and Pathogenesis
- Cervical and Thoracic Myelopathy
- Neurobiology of Language and Bilingualism
Charles University
2006-2024
University Hospital Kralovske Vinohrady
2014
General University Hospital in Prague
1996
Institute for Postgraduate Medical Education
1991-1995
Background and Purpose We sought to determine whether lactate N -acetyl signals measured by proton magnetic resonance spectroscopy (MRS) in the first days after stroke correlate with clinical measures of disability functional outcome. Methods One-dimensional spectroscopic imaging was performed on 32 patients using a 2.1-T magnet. The Toronto Stroke Scale score at time MRS study Barthel Index hospital discharge were determined from patient records. Lesion volume estimated tracing algorithm...
Circumscribed focal atrophy with frontal lobe dementia and progressive aphasia, as described originally by Arnold Pick, has been recognized recently being much more common than previously believed. Although Pick disease became linked argyrophilic inclusions (Pick bodies) swollen neurons cells), the majority of atrophies have findings that are a variation classic histologic features. We discuss Pick's background circumstances led to his major contributions study behavioral neurology. also...
Stroke is a major medical problem and one of the leading causes mortality disability all over in Europe. However, there are significant East–West differences stroke care as well morbidity rates. Central Eastern European countries that formerly had centralized socialist health systems have serious similar problems organizing 20 years after political transition. In Europe, more frequent, rate higher, victims younger than Western High-risk patients live worse environmental conditions,...
We present the clinical, radiological and pathological features of a case cranial hypertrophic pachymeningitis that developed in course mastoiditis petrous apex inflammation responded to immunosuppressive therapy only. Documented by development clinical findings, magnetic resonance imaging, cerebrospinal fluid changes, histopathology otosurgical intervention finally insertion ventriculo-peritoneal shunt, illustrates gradual with consequent hydrocephalus intracranial hypertension. consider...
BACKGROUND: The aim of this study was to assess the effect anticoagulation treatment on platelet aggregation.METHODS: group consisted 24 patients long-term warfarin therapy without any antiaggregation therapy.Platelet aggregation measured using VerifyNow with arachidonic acid (AA) as an inducer in 23 and light transmission aggregometry (LTA) 19 four different agonists.All had their international normalized ratio (INR) checked regularly.RESULTS: mean INR value 2.07 (SD 0.6).The average by...
Abstract Histological observations, published in 1907-12 by A. Alzheimer and more thoroughly O. Fischer, became source of the assumption that brain amyloid neurofibrillary tangles are causing a specific disease leading to dementia. At time, when research over last 30 years has found large variety processes impair performance aging construct Alzheimer´s (AD) is losing its meaning. The communication among neuroscientists will therefore benefit from shedding dichotomy "healthy "versus" AD"and...
Our understanding of the mental deterioration associated with old-age have undergone a number changes over past two centuries and spurred major scientific debates. In 19th century, this disorder was still considered to be an inevitable feature aging. The dawn 20th century offered histological explanation for presenile dementia, Alois Alzheimer credited as discoverer new disease that bears his name. During last quarter twentieth findings were massively applied also late-onset thus virtually...
The clinical aspects and histopathology of dementia are best understood when based on knowledge the historical milestones associated with its development. We studied archive materials visited some psychiatric asylums that were active in Prague during 19th century. <i>Results:</i> gradual recognition histological correlates territory actual Czech Republic from 1830s described, together links to Austrian, German, other foreign psychiatry neurology. A stepwise differentiation...
Abstract A group of 20 persons with cerebral infarctions who had been treated vinpocetine was compared a similar patients other vasoregulative drugs. Two computed tomography (CT) examinations were evaluated for each patient. The initial scan done during the first ten days, and second between 20th 50th day after stroke. Three parameters studied: extension lesion, intensity hypodensity, presence postcontrast enhancement. In criteria, vinpocetine‐treated exhibited better results, whereas third...
Limited information can be obtained as to the availability of neurological in-patient services in former communist countries Eastern and Central Europe. The objective was analyse data received directly from representatives particular countries.The were collected under auspices 'First European Cooperation Neurology Workshop' held April 2000, Trest, Czech Republic. Neurologists 15 post-communist provided their respective countries. Linear trends graphs including reliability value R(2) used...