A5025889427- Antimicrobial Peptides and Activities
- Biochemical and Structural Characterization
- Insect Utilization and Effects
- Mycobacterium research and diagnosis
- Immune Response and Inflammation
- Syphilis Diagnosis and Treatment
- Immune responses and vaccinations
- COVID-19 Impact on Reproduction
- Reproductive tract infections research
- Antibiotic Resistance in Bacteria
- Aquaculture disease management and microbiota
- Venomous Animal Envenomation and Studies
- Cervical Cancer and HPV Research
- Food Allergy and Anaphylaxis Research
- Bee Products Chemical Analysis
- Virology and Viral Diseases
- Lipid Membrane Structure and Behavior
- Bacteriophages and microbial interactions
- Pluripotent Stem Cells Research
- Insect and Pesticide Research
- Phytochemistry and biological activity of medicinal plants
- Tissue Engineering and Regenerative Medicine
- Healthcare and Venom Research
- Reproductive Biology and Fertility
- Pediatric health and respiratory diseases
SMART Reading
2024
Universidade Federal de Goiás
2016-2022
Abstract Induced pluripotent stem cells (iPSCs) hold large potential in regenerative medicine due to their pluripotency and unlimited self‐renewal capacity without the ethical issues of embryonic cells. To provide quality‐controlled iPSCs for clinical therapies, it is essential develop safe cryopreservation protocols long‐term storage, preferably amenable scale‐up automation. We have compared impact two different freezing geometries (bottom‐up conventional radial freezing) on viability...
Intravascular stent infection is a rare complication with high morbidity and mortality; bacteria from the hospital environment form biofilms are often multidrug-resistant (MDR). Antimicrobial peptides (AMPs) have been considered as alternatives to bacterial treatment. We analyzed formation of biofilm on vascular stents also tested inhibition this by AMPs be used treatment or coating. activity antibiofilm were wasp (Agelaia-MPI, Polybia-MPII, Polydim-I) scorpion (Con10 NDBP5.8) against...
Mycobacterium abscessus subsp. massiliense, a rapidly growing mycobacteria (RGM) that is becoming increasingly important among human infectious diseases, virulent and pathogenic presents intrinsic resistance to several antimicrobial drugs might hamper their elimination. Therefore, the identification of new improve current treatment or lower risk inducing urgently needed. Wasp venom primarily comprises peptides are responsible for most biological activities in this poison. Here, novel peptide...
Mycobacterium massiliense is a rapid growing, multidrug-resistant, non-tuberculous mycobacteria that responsible for wide spectrum of skin and soft tissue infections, as well other organs, such the lungs. Antimicrobial peptides had been described broad-spectrum antimicrobial, chemotactic, immunomodulator molecules. In this study we evaluated an antimicrobial peptide derived from scorpion Tityus obscurus anti-mycobacterial agent in vitro vivo. Bioinformatics analyses demonstrated ToAP2 have...
Multi-drug resistant microorganisms have been a growing concern during the last decades due to their contribution in mortality rates worldwide. Antimicrobial peptides are broad spectrum antimicrobial agents that display potent microbicidal activity against wide range of microorganisms. generally rapid mode action reduces risk resistance developing among pathogens. In this study, an peptide derived from scorpion venom, NDBP-5.5, was evaluated Mycobacterium abscessus subsp. massiliense,...
Antimicrobial peptides (AMPs) are small molecules with microbicidal and immunoregulatory activities. In this study we evaluated the anti-inflammatory antimicrobial activities of ToAP3 ToAP4, AMPs from venom Brazilian scorpion Tityus obscurus. To test peptides' activity, murine bone marrow-derived macrophages (BMDMs) or dendritic cells (BMDCs) were stimulated plus LPS to analyze their ability modulate cytokine release as well phenotypic markers. For analysis, indirect activity against...
Abstract Induced pluripotent stem cells (iPSCs) hold large potential on regenerative medicine due to their pluripotency and unlimited self-renewal capacity without the ethical issues of embryonic cells. To provide quality-controlled iPSCs for clinical therapies, it is essential develop safe cryopreservation protocols long-term storage, preferable amenable scale-up automation. We have compared impact two different freezing geometries (bottom-up conventional radial freezing) viability...
Medicinal plants are of great interest for the discovery new biomolecules with diversified effects. Over last decade different outbreaks caused by Mycobacterium abscessus subsp. massiliense have been reported, evidencing it as an important emerging pathogen in underdeveloped countries. This study investigated antimycobacterial activity six Brazilian medicinal plant extracts and their fractions. Hyptis brevipes, Tocoyena formosa, Randia armata, Paullinia pinnata, Lafoensia pacari...