Michael Balas

ORCID: 0000-0002-5948-0331
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About
Contact & Profiles
Research Areas
  • Retinal Diseases and Treatments
  • Retinal and Optic Conditions
  • Retinal Imaging and Analysis
  • Glaucoma and retinal disorders
  • Artificial Intelligence in Healthcare and Education
  • Diversity and Career in Medicine
  • Corneal surgery and disorders
  • Intraocular Surgery and Lenses
  • Ocular Diseases and Behçet’s Syndrome
  • Clinical Reasoning and Diagnostic Skills
  • Retinal and Macular Surgery
  • Global Health Workforce Issues
  • Ophthalmology and Visual Impairment Studies
  • Primary Care and Health Outcomes
  • Spinal Fractures and Fixation Techniques
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Pelvic and Acetabular Injuries
  • Acute Ischemic Stroke Management
  • Glioma Diagnosis and Treatment
  • Immune cells in cancer
  • Drug-Induced Ocular Toxicity
  • Spinal Cord Injury Research
  • Healthcare Policy and Management
  • Surgical Simulation and Training
  • Radiology practices and education

University of Toronto
2021-2025

Deleted Institution
2022-2023

St. Michael's Hospital
2019-2023

University of Alberta
2023

University of British Columbia
2021

St Michaels Hospital
2021

Toronto Western Hospital
2021

University Health Network
2019-2021

McMaster University
2019-2021

Kensington Health
2021

With the rapidly growing field of conversational artificial intelligence (AI), it is becoming increasingly likely that these technologies will revolutionize way physicians diagnose and treat patients. The purpose this study to evaluate use AI language models, specifically ChatGPT, for diagnosis ophthalmic disease, compare existing tools, namely Isabel Pro Differential Diagnosis Generator. Prospective, comparative evaluation ChatGPT in formulating provisional differential diagnoses from a set...

10.1016/j.jfop.2023.100005 article EN cc-by JFO Open Ophthalmology 2023-03-01

Tumor-associated macrophages (TAMs) constitute up to 50% of tumor bulk in glioblastoma (GBM) and play an important role maintenance progression. The recently discovered differences between invading tumour periphery hypoxic core implies that macrophage biology is also distinct by location. This may provide further insight into the observed treatment resistance immune modulation. We hypothesize activation occurs through processes are versus core. therefore investigated regional TAM recruitment...

10.1038/s41598-020-76657-3 article EN cc-by Scientific Reports 2020-11-11

Integrating large language models (LLMs) like GPT-4 into medical ethics is a novel concept, and understanding the effectiveness of these in aiding ethicists with decision-making can have significant implications for healthcare sector. Thus, objective this study was to evaluate performance responding complex ethical vignettes gauge its utility limitations ethicists. Using mixed-methods, cross-sectional survey approach, panel six assessed LLM-generated responses eight vignettes.The main...

10.1136/jme-2023-109549 article EN Journal of Medical Ethics 2023-11-09

ObjectiveTo evaluate the performance of an artificial intelligence (AI) large language model, ChatGPT (version 4.0), for common retinal diseases, in accordance with American Academy Ophthalmology (AAO) Preferred Practice Pattern (PPP) guidelines.DesignA cross-sectional survey study design was employed to compare responses made by established clinical guidelines.ParticipantsResponses AI were reviewed a panel three vitreoretinal specialists evaluation.MethodsTo investigate ChatGPT's...

10.1016/j.jcjo.2024.06.001 article EN cc-by Canadian Journal of Ophthalmology 2024-08-01

Purpose: To compare the performance and cost-effectiveness of DeepSeek-R1 with OpenAI o1 in diagnosing managing ophthalmology clinical cases. Study Design: Cross-sectional evaluation. Methods: A total 300 cases spanning 10 different subspecialties were collected from StatPearls. Each case presented a multiple-choice question regarding diagnosis or management case. was accessed through its public chat-based interface, while queried via an Application Program Interface (API) standardized...

10.1101/2025.02.10.25322041 preprint EN cc-by-nd medRxiv (Cold Spring Harbor Laboratory) 2025-02-12

Recording and stimulating from the peripheral nervous system are becoming important components in a new generation of bioelectronics systems. Although neurostimulation has seen history successful chronic applications humans, nerve recording humans chronically remains challenge. Multi-contact cuff electrode configurations have potential to improve selectivity. We introduce idea using convolutional neural network (CNN) associate recordings individual naturally evoked compound action potentials...

10.1088/1741-2552/ab4ac4 article EN Journal of Neural Engineering 2019-10-03

To investigate the effects of COVID-19 pandemic on case volumes and wait-times for ophthalmic surgery in Ontario, Canada.

10.2147/opth.s409479 article EN cc-by-nc Clinical ophthalmology 2023-06-01

Purpose: To assess the accuracy and readability of responses generated by artificial intelligence model, ChatGPT (version 4.0), to questions related 10 essential domains orbital oculofacial disease. Methods: A set 100 diagnosis, treatment, interpretation diseases was posed 4.0. Responses were evaluated a panel 7 experts based on appropriateness accuracy, with performance scores measured 7-item Likert scale. Inter-rater reliability determined via intraclass correlation coefficient. Results:...

10.1097/iop.0000000000002552 article EN Ophthalmic Plastic and Reconstructive Surgery 2023-11-16

Glaucoma refers to a spectrum of progressive optic neuropathies and remains the leading cause irreversible blindness worldwide. Its insidious onset poses serious challenges conventional diagnostic methods clinicians striving detect early-stage disease for timely effective intervention. Artificial intelligence (AI) has demonstrated its ability process analyze large datasets which can help identify subtle changes in early glaucomatous clinical presentation. This study reviews current state AI...

10.3390/jcto2020005 article EN Journal of Clinical & Translational Ophthalmology 2024-05-25

Adaptive Optics (AO) has emerged as a revolutionary technology in ophthalmology, offering an unprecedented view into the eye's microstructures with high-resolution imaging capabilities. Originally developed for astronomy, AO been adapted to correct optical aberrations, enabling visualization of individual cellular structures such photoreceptors, retinal pigment epithelium cells, and capillaries within vasculature. This review provides comprehensive overview AO, discussing its historical...

10.1016/j.jfop.2024.100116 article EN cc-by JFO Open Ophthalmology 2024-06-06

Purpose: To describe the multimodal imaging findings associated with benign yellow dot maculopathy. Methods: A case report was analyzed. Results: healthy 42-year-old White man evaluated after several weeks of photopsias and an inferior retinal tear in right eye. The treated laser retinopexy. fundus examination showed numerous small, yellow, subretinal lesions around macula eye only. patient had no known systemic conditions unremarkable family ocular history, 20/20 visual acuity both eyes....

10.1177/24741264241260489 article EN cc-by Journal of VitreoRetinal Diseases 2024-06-16

Early surgical intervention to decompress the spinal cord and stabilize column in patients with acute traumatic thoracolumbar injury (TLSCI) may lessen risk of developing complications improve outcomes. However, there has yet be agreement on what constitutes "early" surgery; reported thresholds range from 8 72 h. To address this knowledge gap, we conducted an observational cohort study using data American College Surgeons (ACS) Trauma Quality Improvement Program (TQIP) 2010 2016. The...

10.1089/neu.2020.7525 article EN Journal of Neurotrauma 2021-03-16

Abstract Modulation of tumor microenvironment is an emerging frontier for new therapeutics. However in meningiomas, the most frequent adult brain tumor, correlation with phenotype scarcely studied. We applied a variety systems biology approaches to bulk transcriptomics explore immune environments both skull base and convexity (hemispheric) meningiomas. hypothesized that more benign meningiomas parallels relative composition activity cells oppose growth and/or survival. firstly gene...

10.1038/s41598-020-65365-7 article EN cc-by Scientific Reports 2020-06-03

<h3>Background:</h3> Differences in physician income by gender have been described numerous jurisdictions, but few studies looked at a Canadian cohort with adjustment for confounders. In this study, we aimed to understand differences fee-for-service payments men and women physicians Ontario. <h3>Methods:</h3> We conducted cross-sectional analysis of all Ontario who submitted claims the Health Insurance Plan (OHIP) 2017. For each physician, gathered demographic information from College...

10.1503/cmaj.210437 article EN cc-by-nc-nd Canadian Medical Association Journal 2021-10-17

BACKGROUND AND OBJECTIVES: It is believed that early tracheostomy in patients with traumatic cervical spinal cord injury (SCI) may lessen the risk of developing complications and reduce duration mechanical ventilation critical care stay. This study aims to assess whether beneficial SCI. METHODS: We conducted a retrospective cohort using data from American College Surgeons Trauma Quality Improvement Program database 2010 2018. Adult diagnosis acute complete (ASIA A) SCI who underwent surgery...

10.1227/neu.0000000000002575 article EN Neurosurgery 2023-06-21

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10.1017/cjn.2022.317 article EN Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques 2022-11-10
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