A5070891219- Air Quality and Health Impacts
- Nanoparticles: synthesis and applications
- Energy and Environment Impacts
- Diet, Metabolism, and Disease
- Carcinogens and Genotoxicity Assessment
- Food composition and properties
- Heavy Metal Exposure and Toxicity
- Agriculture Sustainability and Environmental Impact
- Gut microbiota and health
- Botanical Research and Chemistry
- Selenium in Biological Systems
- Alcohol Consumption and Health Effects
- Phytochemicals and Antioxidant Activities
- Microbial Metabolites in Food Biotechnology
- Inflammatory Bowel Disease
- Digestive system and related health
- Diet and metabolism studies
- Ruminant Nutrition and Digestive Physiology
- Hops Chemistry and Applications
- Liver Disease Diagnosis and Treatment
- Nutrition and Health Studies
- Polysaccharides and Plant Cell Walls
- Probiotics and Fermented Foods
- Legume Nitrogen Fixing Symbiosis
- Energy, Environment, and Transportation Policies
Warsaw University of Life Sciences
2015-2024
Institute of Biochemistry and Biophysics, Polish Academy of Sciences
2023
University of Warsaw
2023
Jan Długosz University
2023
Państwowa Wyższa Szkoła Zawodowa w Nowym Sączu
2023
Nutrition Sciences (Belgium)
2014
Adam Mickiewicz University in Poznań
1995
ABSTRACT Silver nanoparticles (AgNPs) are the most commonly used owing to their antimicrobial properties. The motivation of present study was (1) analyze effect silver particle size on rat tissue distribution at different time points, (2) determine accumulation AgNPs in potential target organs, (3) intracellular and (4) examine excretion by urine feces. were characterized dynamic light scattering (DLS), zeta measurements, BET surface area transmission scanning electron microscopy. (20 200...
Metabolic syndrome (MetS) is defined as the co-occurrence of at least three following metabolic disorders: abdominal obesity, hypertriglyceridemia, low high-density lipoprotein cholesterol (HDL-C), high blood glucose, and hypertension. The treatment MetS involves lifestyle changes, including an appropriate diet. In addition to weight reduction, it crucial search for optimal nutritional patterns that are highly effective in optimizing other markers, such glucose lipid metabolism, reducing...
Effect of oat beta-glucans on colon rats.
Typical alcohol consumption begins in the adolescence period, increasing risk of alcoholic liver disease (ALD) adolescents and young adults, while pathophysiology ALD is still not completely understood, it believed that oxidative stress may be major contributor initiates promotes progression damage. The aim present study was to assess influence on markers inflammation animal model prolonged using various beverages. In a homogenic group 24 male Wistar rats (4 groups—6 animals per group),...
Background: Crohn’s disease (CD) is characterized by chronic inflammation of the gastrointestinal tract with alternating periods exacerbation and remission. The aim this study was to determine time-dependent effects dietary oat beta-glucans on colon apoptosis autophagy in CD rat model. Methods: A total 150 Sprague–Dawley rats were divided into two main groups: healthy control (H) a TNBS (2,4,6-trinitrobenzosulfonic acid)-induced colitis (C) group, both including subgroups fed feed without...
Background: Oat beta-glucans are polysaccharides, belonging to soluble fiber fraction, that show a wide spectrum of biological activity. The aim this study was evaluate the time-dependent antioxidative effect chemically pure oat beta-glucan fractions, characterized by different molar mass, which were fed animals with early stage 2,4,6-trinitrobenzene sulfonic acid (TNBS) - induced colitis. Methods: conducted on 150 adult male Sprague Dawley rats assigned two groups-healthy control (H) and...
The World Health Organization (WHO) reported that alcohol consumption is a serious problem in adolescents. aim of the study was to assess influence time exposure various alcoholic beverages on body mass as well select parameters liver antioxidant defense adolescent Wistar rats. Thirty-day-old animals were divided into 12 groups (six each): control and receiving containing 10% (ethanol, red wine, beer), observed for two, four, six weeks. weight gain energy supply analyzed assessment. catalase...
Due to their potent antibacterial properties, silver nanoparticles (AgNPs) are widely used in industry and medicine. However, they can cross the brain–blood barrier, posing a risk brain its functions. In our previous study, we demonstrated that oral administration of bovine serum albumin (BSA)-coated AgNPs caused an impairment spatial memory dose-independent manner. this evaluated effects coating material on cognition, functioning, neurotransmitter levels rat hippocampus. coated with BSA...
The prevalence of gastritis in humans is constantly growing and a prediction an increase this health problem observed many countries. For reason, effective dietary therapies are sought that can alleviate the course disease. objective study was to determine effect chemically pure oat beta-glucan preparations with different molar masses, low or high, used for 30 days patients histologically diagnosed chronic gastritis. enrolled 48 people both genders ages recruited from 129 diagnosis. Before...
Nanosilver is a popular nanomaterial, the potential influence of which on humans serious concern. Herein, we exposed male Wistar rats to two regimens: repeated oral dose 30 mg/kg bw silver nanoparticles (AgNPs) over 28 days and single-dose injection 5 AgNPs. At three different time points, assessed antioxidant defense, oxidative stress inflammatory parameters in colon, as well toxicity markers liver plasma. Both experimental scenarios showed increased inflammation colon. Oral administration...
Oat beta-glucan is one of the soluble dietary fibre fractions with a wide spectrum biological activities such as anti-inflammatory and anti-tumour properties. In present study, effect low-molar-mass oat isolate (OβGl) on level autophagy apoptosis in colorectum rats induced early stages colorectal cancer was investigated. Forty-five male Sprague-Dawley were divided into two main groups: control azoxymethane-induced early-stage carcinogenesis (CRC). Both groups three subgroups fed standard...
While the impact of emissions from combustion fossil fuel on human health has been extensively studied, current knowledge exhaust exposure biofuels provides limited and inconsistent information about its neurotoxicity. The objective present work was to compare gene expression patterns in rat frontal cortex hippocampus after diesel (DEE) two 1st generation fuels, 7% fatty acid methyl esters (FAME) (B7) 20% FAME (B20), a 2nd FAME/hydrotreated vegetable oil (SHB20: synthetic hydrocarbon...
Blackcurrant (BC) is a well-known and appreciated berry fruit in our country Poland the largest BC producer among European Union countries second, after Russia, world. Due to short shelf life of BC, its consumption fresh form relatively low , therefore berries are processed into juices, jams, jellies, freeze-dried products or alcoholic beverages. The high nutritional value result from content bioactive compounds (among others, vitamin C, anthocyanins, pectins, organic acids, as well...
Increased use of biofuels raises concerns about health effects new emissions. We analyzed relative lung effects, on Fisher 344 rats, diesel engine exhausts emissions (DEE) from a Euro 5-classified running petrodiesel fuel containing 20% rapeseed methyl esters (B20) with and without particulate filter (DPF). One group animals was exposed to DEE for 7 days (6 h/day), another 28 h/day, 5 days/week), both DPF. The (n = 7/treatment) were in whole body exposure chambers. Animals breathing clean...
The primary aim of this experiment was to investigate the bioactivity potential and polyphenolic profile defatted raspberry seeds (DRS) extracts from three varieties (Willamette, Meeker, Polka) using in vitro tests HPLC-DAD UHPLC-Triple-TOF-MS. Extracts were obtained ultrasound-assisted extraction (UAE) or hydrolysis. antioxidant activity tested 1,1-diphenyl-2-picrylhydrazyl (DPPH), 2,2′-azinobis-(3-ethylbenzothiazoline-6-sulfonic) cation (ABTS), ferric reducing power (FRAP) assays....
Factors that reduce the risk of developing colorectal cancer include biologically active substances. In our previous research, we demonstrated anti-inflammatory, immunomodulatory, and antioxidant effects oat beta-glucans in gastrointestinal disease models. The aim this study was to investigate effect an 8-week consumption a diet supplemented with low-molar-mass beta-glucan two doses on potential, inflammatory parameters, colonic metabolomic profile azoxymethane(AOM)-induced early-stage large...
It has been broadly reported that the production of animal-derived foods significantly contributes to environmental footprint agri-food sector, considering, among others, such indicators as land use, greenhouse gas emissions, and water footprint. However, sustainability aspects whole diets (i.e., more plant-based vs. meat-containing) have studied so far a limited extent, in many cases not taking into consideration various regional settings, which great extent determine meat- other foods’...