- Cancer Treatment and Pharmacology
- Lymphatic System and Diseases
- Childhood Cancer Survivors' Quality of Life
- Cancer survivorship and care
- Pain Mechanisms and Treatments
- Effects of Vibration on Health
- Chemotherapy-related skin toxicity
- Complementary and Alternative Medicine Studies
- Botulinum Toxin and Related Neurological Disorders
- Cancer-related cognitive impairment studies
- Myofascial pain diagnosis and treatment
- Diabetes Management and Education
- Physical Activity and Health
- Multiple Myeloma Research and Treatments
- Management of metastatic bone disease
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Amyotrophic Lateral Sclerosis Research
- Health and Lifestyle Studies
- Glioma Diagnosis and Treatment
- Pediatric Pain Management Techniques
- Exercise and Physiological Responses
- Ethics and Legal Issues in Pediatric Healthcare
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Muscle and Compartmental Disorders
- Phytochemistry and Bioactive Compounds
University of Basel
2017-2025
German Sport University Cologne
2013-2024
University Hospital of Basel
2018-2024
Prokop (Czechia)
2015
Straumann (Switzerland)
2015
University Medical Center Freiburg
2009-2014
University of Freiburg
2014
Exercise has been proven to reduce the risk and progression of various diseases, such as cancer, diabetes neurodegenerative disorders. Increasing evidence suggests that exercise affects cytokine profile changes distribution function tumor-competitive immune cells. Initial studies have shown different interventions are associated with epigenetic modifications in tissues cell types, muscle, fat, brain blood. The present investigation examines effect an intense endurance run (half marathon) on...
Introduction Thanks to modern therapy, the survival rate for children with cancer is constantly improving. However, strong treatment chemotherapy also takes its toll. It leads delays in motor milestones (e.g. running, climbing), which limits social reintegration as well quality of life (Bjornard et al. 2018). Peripheral neuropathy (CIPN) a common side effect and crucial cause many functional disorders. causes severe symptoms such loss sensation, pain, numbness, absent reflexes balance...
Introduction Chemotherapy-induced peripheral neuropathy (CIPN) is a highly prevalent and clinically relevant adverse effect of chemotherapy, negatively impacting patient quality life. The lack effective preventive or therapeutic options regarding CIPN often requires changes in cancer therapy, potentially resulting reduced survival. Meanwhile 10 studies have shown that specific exercise can reduce symptoms (Streckmann eu al. 2021). In our most recent study et 2024) we been able to show even...
Introduction Modern therapy has improved survival for children with cancer. However, treatment unintended consequences. More and more studies are showing that have persisting motor sensory dysfunctions, such as loss of sensation, numbness, pain, absent reflexes well balance control. Developmental milestones walking, running, jumping or climbing delayed which negatively impacts their quality life social reintegration (Bjornard et al. 2018). Consequently, survivors less inclined to participate...
Chemotherapy-induced peripheral neuropathy (CIPN) is a common and clinically relevant side effect of chemotherapy. Approximately 50% all leukemia, lymphoma, colorectal- breast cancer patients are affected. CIPN induced by neurotoxic chemotherapeutic agents can manifest with sensory and/or motor deficits. It associated significant disability poor recovery. Common symptoms include pain, altered sensation, reduced or absent reflexes, muscle weakness, balance control insecure gait. These not...
Background: Improvements in survival rates pediatric oncology have resulted a growing need to identify adverse effects and improve rehabilitation this population. Objective: This cross-sectional study aimed investigate active ankle dorsiflexion (DF) range of motion (ROM), gait, walking efficiency, motor performance mixed childhood cancer survivor population comparison healthy peers. Methods: Active DF-ROM (goniometer), gait (Microgate Optogait 2D Gait Analysis), efficiency (6-minute walk...
Einleitung: In der Versorgung onkologischer Patienten wird korperliches Training zunehmend als wichtige supportive Therapie angesehen. Bisherige Studien haben ein breites Spektrum an Erhebungsmethoden fur primare und sekundare End-punkte verwendet. Um die Vergleichbarkeit Qualitat zukunftiger zu verbessern, leitet diese Arbeit unter Berucksichtigung spezifischer Aspekte bei on-kologischen konkrete Empfehlungen ab Erhebung 1) Ausdau-erleistungsfahigkeit, 2) Kraftleistungsfahigkeit, 3)...
To assess a whole-body vibration (WBV) intervention for children after cancer treatment.Eleven inpatient anticancer therapy participated in 12-week supervised WBV intervention, which consisted of one 9- to 13-minute session per week, with 5 9 minutes' overall time. Feasibility was defined as the ability participate training without reporting adverse events. The number offered and completed sessions, program acceptance, measures function were assessed.Nine participants any WBV-related...
Die Chemotherapie-induzierte periphere Polyneuropathie (CIPN) ist eine der relevantesten Therapie-assoziierten Nebenwirkungen. Sie führt zu motorischen und sensorischen Dysfunktionen, die zum einen Lebensqualität Patienten reduzieren anderen medizinische Therapie beeinträchtigen. Derzeit besteht kein effektives Behandlungskonzept zur Behandlung CIPN. Vielversprechend derzeit Sporttherapie. Basierend auf dem aktuellsten wissenschaftlichen Stand bieten sowohl Sensomotoriktraining als auch...
Abstract Whole-body vibration (WBV) is a feasible and potentially beneficial exercise strategy for managing neuromuscular impairments like decreased strength or flexibility, mobility limitations bone health in pediatric cancer survivors. However, as starting rehabilitation early possible recommended to preserve physical function, this study investigated the feasibility of WBV patients receiving treatment first diagnosis. Eleven (various types cancer, ages 7–17) participated supervised...
Introduction The widespread prevalence of type 2 diabetes (T2D) not only influences patients’ daily lives but also has an economic impact on society. Increasing physical activity and a healthy diet can delay the progression T2D. Although there are evidence-based recommendations activity, patients with T2D have difficulties implementing them. An appropriate lifestyle intervention address this problem. Methods analysis This study is based need to develop that helps establish behavioural...