- Spaceflight effects on biology
- Effects of Vibration on Health
- Bone health and osteoporosis research
- Sports Performance and Training
- Musculoskeletal pain and rehabilitation
- Muscle metabolism and nutrition
- Sports injuries and prevention
- Cardiovascular and exercise physiology
- Muscle Physiology and Disorders
- Body Composition Measurement Techniques
- Muscle activation and electromyography studies
- Ergonomics and Musculoskeletal Disorders
- Nutrition and Health in Aging
- Lower Extremity Biomechanics and Pathologies
- Space Exploration and Technology
- High Altitude and Hypoxia
- Bone fractures and treatments
- Noise Effects and Management
- Exercise and Physiological Responses
- Thermoregulation and physiological responses
- Balance, Gait, and Falls Prevention
- Occupational Health and Performance
- Genetics and Physical Performance
- Heart Rate Variability and Autonomic Control
- Fibromyalgia and Chronic Fatigue Syndrome Research
Deutsches Zentrum für Luft- und Raumfahrt e. V. (DLR)
2016-2025
University Hospital Cologne
2013-2025
University of Cologne
2014-2024
Manchester Metropolitan University
2009-2022
Linde (Germany)
2013-2022
Institute of Aviation Medicine
2017-2019
Institute of Biomedical Problems
2019
S. P. Korolev Rocket and Space Corporation Energia (Russia)
2019
Linde (United States)
2019
Baylor College of Medicine
2017
Vibration exercise (VE) is a new neuromuscular training method which applied in athletes as well prevention and therapy of osteoporosis. The present study explored the physiological mechanisms fatigue by VE 37 young healthy subjects. Exercise cardiovascular data were compared to progressive bicycle ergometry until exhaustion. was performed two sessions, with 26 Hz vibration on ground plate, combination squatting plus additional load (40% body weight). After VE, subjectively perceived...
Insulin sensitivity and metabolic flexibility decrease in response to bed rest, but the temporal causal adaptations human skeletal muscle metabolism are not fully defined. Here, we use an integrative approach assess during rest provide a multi-system analysis of how circulatory system adapt short- long-term (German Clinical Trials: DRKS00015677). We uncover that intracellular glycogen accumulation after short-term accompanies rapid reduction systemic insulin less GLUT4 localization at cell...
Summary The effects of hard squatting exercise with (VbX+) and without (VbX−) vibration on neuromuscular function were tested in 19 healthy young volunteers. Before after the exercise, three different tests performed: maximum serial jumping for 30 s, electromyography during isometric knee extension at 70% voluntary torque, quantitative analysis patellar tendon reflex. Between VbX+ VbX− values, there was no difference found under baseline conditions. Time to exhaustion significantly shorter...
Summary Ageing compromises locomotor capacity and is associated with an increased risk of falls. Several lines evidence indicate that both changes in muscle mass performance are causative. Most studies, however, do not discern between effects ageing, sedentarism comorbidity. The present study compares the age cross section, force power physically competent self‐selected subjects different groups. A total 169 women 89 men 18 88 years, without any disease, impairment or medication affecting...
Study Design. A randomized controlled trial with a 6-month follow-up period was conducted. Objective. To compare lumbar extension exercise and whole-body vibration for chronic lower back pain. Summary of Background Data. Chronic pain involves muscular as well connective neural systems. Different types physiotherapy are applied its treatment. Industrial is regarded risk factor. Recently, has been developed new type physiotherapy. It thought to activate muscles via reflexes. Methods. In this...
Vibration exercise (VbX) is a new type of physical training to increase muscle power. The present study was designed assess the influence whole-body VbX on metabolic Specific oxygen uptake (sV˙O2) assessed, testing hypotheses that sV˙O2 increases with frequency vibration (tested in 10 males) and amplitude 8 males), VbX-related enhanced by increased force males). With 5 mm, linear found from frequencies 18 34 Hz (p < 0.01). Each cycle evoked an consumption approximately 2.5 µl × kg-1. At 26...
Information on muscle fiber type composition is of great importance in physiology and athletic performance. Because there are only a few techniques available that noninvasively accurately provide an estimate composition, the development additional alternative approaches required.Twenty-seven participants (21 men, 6 women) with average age 43 ± 18 yr, height 175 7 cm, mass 74 12 kg participated study. Delay, contraction, half relaxation times were calculated from tensiomyographic radial...
Mechanical loading is thought to be a determinant of bone mass and geometry. Both ground reaction forces tibial strains increase with running speed. This study investigates the hypothesis that surrogates strength in male female master sprinters, middle long distance runners race-walkers vary according discipline-specific mechanical from sedentary controls. Bone scans were obtained by peripheral Quantitative Computed Tomography (pQCT) tibia radius 106 52 runners, 93 49 who competing at...
Background Achilles tendinopathy is commonly reported by athletes involved in activities that include running and jumping. Despite the prevalence of problem, causative factors remain poorly understood. Hypothesis In Masters track field athletes, there no influence age, gender, weight, height, impact profile developing tendinopathy. Study Design Cross-sectional study; Level evidence, 3. Methods During European Veterans Athletics Championships Poznań, Poland, July 2006, 178 (110 men 68 women;...
This investigation aimed to compare the response of young and older adult men bed rest (BR) subsequent rehabilitation (R). Sixteen (OM, age 55-65 yr) seven (YM, 18-30 were exposed a 14-day period BR followed by 14 days R. Quadriceps muscle volume (QVOL), force (QF), explosive power (QP) leg extensors; single-fiber isometric (Fo); peak aerobic (V̇o2peak); gait stride length; three metabolic parameters, Matsuda index insulin sensitivity, postprandial lipid curve, homocysteine plasma level,...
Bending, in addition to compression, is recognized be a common loading pattern long bones animals. However, due the technical difficulty of measuring bone deformation humans, our current understanding patterns humans very limited. In present study, we hypothesized that bending and torsion are important regimes human tibia. vivo tibia segment was assessed during walking running utilizing novel optical approach. Results suggest proximal primarily bends posterior (bending angle: 0.15°-1.30°)...
Without effective countermeasures, the musculoskeletal system is altered by microgravity environment of long-duration spaceflight, resulting in atrophy bone and muscle tissue, as well deficits function cartilage, tendons, vertebral disks. While inflight countermeasures implemented on International Space Station have evidenced reduction loss low-Earth orbit missions several months length, important knowledge gaps must be addressed order to develop strategies for managing human health...
Background Muscle mass and function are perturbed by immobilization remobilization. When muscle changes, the quality quantity of extracellular matrix protein, particularly collagens, change with it. In this study, we investigated temporal profile three peptide biomarkers derived from turnover collagen type III VI in a long-term remobilization study. We also compared individual biomarker levels Lean body Mass (LBM) changes therein, hypothesizing that these would be remodeling processes...
Whole-body vibration (WBV) is an exercise modality or treatment/prophylaxis method in which subjects (humans, animals, cells) are exposed to mechanical vibrations through a vibrating platform device. The defined by their direction, frequency, magnitude, duration, and the number of daily bouts. Subjects can be while performing exercises, hold postures, sitting, lying down. Worldwide, WBV has attracted significant attention, studies rising. To interpret, compare, aggregate studies, correct,...