About
Contact & Profiles
A5102774935
Research Areas
- Vibrio bacteria research studies
- Autophagy in Disease and Therapy
- Antibiotic Resistance in Bacteria
- Child Nutrition and Water Access
- Reproductive tract infections research
- Synthesis and bioactivity of alkaloids
- Drug Transport and Resistance Mechanisms
- Escherichia coli research studies
Harvard University
2014-2024
Brigham and Women's Hospital
2014
ABSTRACT We investigated the roles of Vibrio cholerae high-molecular-weight bifunctional penicillin binding proteins, PBP1a and PBP1b, in fitness this enteric pathogen. Using a screen for synthetic lethality, we found that V. PBP1b like their Escherichia coli homologues, are each essential absence other other's putative activator, outer membrane lipoproteins LpoA LpoB, respectively. Comparative analyses mutants suggest PBP1a/LpoA play more prominent role generating and/or maintaining...
10.1128/iai.00012-14
article
EN
Infection and Immunity
2014-03-11
10.1016/j.chom.2024.09.014
article
EN
Cell Host & Microbe
2024-10-17
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