A5100430706- Machine Learning in Bioinformatics
- Energy Efficient Wireless Sensor Networks
- RNA and protein synthesis mechanisms
- Higher Education and Teaching Methods
- Fractal and DNA sequence analysis
- Education and Work Dynamics
- Genomics and Phylogenetic Studies
- Technology and Security Systems
- Protein Structure and Dynamics
- Distributed Control Multi-Agent Systems
- Mobile Ad Hoc Networks
- Educational Technology and Assessment
- Security in Wireless Sensor Networks
- Network Security and Intrusion Detection
- EFL/ESL Teaching and Learning
- Cancer-related gene regulation
- Advanced biosensing and bioanalysis techniques
- Advanced Decision-Making Techniques
- Distributed and Parallel Computing Systems
- Modular Robots and Swarm Intelligence
- Computational Drug Discovery Methods
- Product Development and Customization
- Inflammatory Bowel Disease
- Neural Networks Stability and Synchronization
- Cloud Computing and Resource Management
Anhui University
2018-2025
Shanxi Academy of Medical Sciences
2025
Shanxi Medical University
2025
Qinghai University
2023
Animal Science Research Institute
2023
Hebei University of Engineering
2014-2023
Wuhan University
2023
Ningbo University
2022
Ningbo Medical Center Lihuili Hospital
2022
Shandong University of Technology
2018-2021
Accurate diagnosis requires the development of multiple-guaranteed DNA circuits. Nevertheless, for reliable multiplexed molecular imaging, existing circuits are limited by poor cell-delivering homogeneity due to their cumbersome and dispersive reactants. Herein, we developed a compact-yet-efficient hierarchical hybridization (HDH) circuit in situ simultaneous analysis multiple miRNAs, which could be further exploited specifically discriminating cancer cells from normal ones. By integrating...
Building dynamic biological networks, especially DNA circuits, has provided a powerful prospect for exploring the intrinsic regulation processes of live cells. Nevertheless, efficient intracellular microRNA analysis, available multi-component circuits are constrained by their limited operating speed and efficiency due to free diffusion reactants. Herein, we developed an accelerated Y-shaped catalytic (YDC) circuit high-efficiency imaging microRNA. By grafting hairpin assembly (CHA) reactants...
Connexins (Cxs) are a family of protein subunits constituting gap junctions, which facilitate exchanges molecules important for cellular signaling and metabolic activities intercellularly or between different regions the cytoplasm in same cells. Mutations Cxs major cause nonsyndromic childhood deafness, mostly found Cx26 Cx30 expressed cochlear supporting cells fibrocytes. So far, little is known about functional contribution other types Here, we show that Cx29 was highly cochlea. The...
ABSTRACT With the advancement of computer and information technology, cyber crime is now becoming one most significant challenges facing law enforcement organizations. Cyber crimes are generally referred as criminal activities that use computers or networks. An understanding characteristics nature important in helping research communities find ways to effectively prevent them. Most existing focuses more on attacks attack models, including either actual imaginary/possible over all layers...
Antarctic krill oil (AKO) is susceptible to oxidation due the high unsaturation degree of bioactive substances. Herein, a lipidomics method for in situ monitoring dynamic characteristics AKO was explored based on electric soldering iron ion source (ESII) coupling with rapid evaporative ionization mass spectrometry (REIMS). The profiles at different storage periods were successfully acquired. On basis principal component analysis and orthogonal partial least-squares analysis, obtained REIMS...
This study was carried out to investigate the enzymatic hydrolysis conditions on properties of protein hydrolysate from fish muscle marine species Collichthys niveatus. About 160 samples were tested, and analyzed found be a lean with low fat (1.77 ± 0.01%) high (16.76 1.21%). Fish C. niveatus carefully collected hydrolyzed four commercial enzymes: Alcalase, Neutrase, Protamex, Flavourzyme under recommended by manufacturers. Among tested proteases, Neutrase catalyzed process most effectively...
Based on the chaos game representation, a 2D graphical representation of protein sequences was introduced in which 20 amino acids are rearranged cyclic order according to their physicochemical properties. The Euclidean distances between corresponding from 2-D representations computed find matching (or conserved) fragments two proteins. Again, cumulative distance 2D-graphical is defined compare similarity protein. And, examination among ND5 proteins nine species shows utility our approach.
Lysine acetylation is a major post-translational modification. It plays vital role in numerous essential biological processes, such as gene expression and metabolism, related to some human diseases. To fully understand the regulatory mechanism of acetylation, identification sites first most important. However, experimental protein often time consuming expensive. Therefore, alternative computational methods are necessary. Here, we developed novel tool, KA-predictor, predict species-specific...
In this paper, we propose a divide and conquer based surveillance framework, in which large area is divided into small areas by critical points lines. Sensor nodes, sinks, robots, RFID tags are all used. We deploy sensor nodes along lines only instead of over the region. Our aim to do with efficient deployment detect then track even capture targets, e.g., an intrusion tank or forest fire, collaboration robots nodes.
Abstract Sensor networks are adopted in many surveillance applications. A traditional method for such applications is to deploy sensor nodes all over the region order cover as much area possible. However, this way not only waste huge amounts of money and resources, but it also unnecessary unrealistic sometimes. It provides garbage form dead batteries. invokes data collisions places a serious burden on network protocols. In applications, we have no need detail every point inside area, some...
This study aimed to investigate the molecular mechanisms of compound herba Sarcandrae aerosol, also known as Fufang Zhongjiefeng (FFZJF) in treating chronic pharyngitis (CP) using network pharmacology and vivo experimental approaches.Active compounds putative targets five herbs FFZJF were identified from Traditional Chinese Medicine Systems Pharmacology Database Analysis Platform, Chemistry Database, Swiss Target Prediction databases. The therapeutic CP obtained OMIM, Durgbank, DisGeNT, GAD...
Recent advances have witnessed the success and popularity of cloud computing, which represents a new business model computing paradigm. The feature on-demand provisioning computational, storage, bandwidth resources has driven modern businesses into services. is considered cutting edge technology it solely relied on by many large technology, business, media companies such as Netflix or Salesforce.com. However, in addition to benefit at hand, security issues been long-term concern for are main...
Abstract Protein‐DNA interactions play an important role in biological progress, such as DNA replication, repair, and modification processes. In order to have a better understanding of its functions, the one most steps is identification DNA‐binding proteins. We propose protein predictor, namely, RF‐SVM, which contains four types features, that is, pseudo amino acid composition (PseAAC), distribution (AAD), adjacent frequency (ACF) Local‐DPP. Random Forest algorithm utilized for selecting top...
Many scientific workflow applications often have deadline constraint such that all tasks of application need to be finished within user-specified time. Though Grid systems high performance, which provide an important infrastructure for executing workflow, dynamic nature resources makes it very difficult schedule and satisfy the given deadline. For this issue, a M/M/C queuing model was adopted service capacity grid resource. Under dynamic, unreliable environment, based on system theory,...
A laser irradiation desorption (LID) method is developed using a 450 nm blue semiconductor and gas chromatography mass spectrometry (GC/MS) for analyzing the flavor of Antarctic krill oil ( Euphausia superba ). The experimental parameters LID are optimized by response surface methodology (RSM), optima obtained as follows; power (10 W), time (5 min), sample volume (3 g). results show that total 41 volatile molecular species detected, including six alcohols, 10 aldehydes, five ketones, 14...