Xuying Nan

ORCID: 0000-0003-0230-0106
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Research Areas
  • Machine Learning in Bioinformatics
  • Photopolymerization techniques and applications
  • Fractal and DNA sequence analysis
  • RNA and protein synthesis mechanisms
  • Advanced Polymer Synthesis and Characterization
  • Genomics and Phylogenetic Studies
  • Luminescence and Fluorescent Materials
  • Molecular Sensors and Ion Detection
  • Photochromic and Fluorescence Chemistry
  • Dyeing and Modifying Textile Fibers
  • Dental materials and restorations
  • Phytochemical compounds biological activities
  • Analytical Chemistry and Sensors
  • Silk-based biomaterials and applications
  • Cancer-related molecular mechanisms research
  • Protein Structure and Dynamics
  • Catalysis for Biomass Conversion
  • Photodynamic Therapy Research Studies
  • Plant Gene Expression Analysis
  • TiO2 Photocatalysis and Solar Cells
  • Catalysis and Hydrodesulfurization Studies
  • Pigment Synthesis and Properties
  • Traditional and Medicinal Uses of Annonaceae
  • Nanofabrication and Lithography Techniques
  • Skin Protection and Aging

Hainan Normal University
2017-2022

Changsha Medical University
2021

Zhejiang Sci-Tech University
2006-2018

Zhejiang University of Science and Technology
2012

Abstract On the basis of a selected pair physicochemical properties amino acids, we introduce dynamic 2D graphical representation protein sequences. Then, and compare two numerical characterizations graphs as descriptors to analyze nine ND5 proteins. The approach is simple, convenient, fast. Proteins 2008. © 2008 Wiley‐Liss, Inc.

10.1002/prot.22110 article EN Proteins Structure Function and Bioinformatics 2008-06-05

Abstract A (two‐dimensional) 2D graphical representation of protein sequences based on six physicochemical properties amino acids is outlined. The numerical characterization graphs given as descriptors sequences. It not only useful for comparative study proteins but also encoding innate information about the structure proteins. coefficient determination proposed a new similarity/dissimilarity measure. Finally, simple example taken to highlight behavior measure from ND6 (NADH dehydrogenase...

10.1002/jcc.21391 article EN Journal of Computational Chemistry 2009-09-23

Based on the chaos game representation, a 2D graphical representation of protein sequences was introduced in which 20 amino acids are rearranged cyclic order according to their physicochemical properties. The Euclidean distances between corresponding from 2-D representations computed find matching (or conserved) fragments two proteins. Again, cumulative distance 2D-graphical is defined compare similarity protein. And, examination among ND5 proteins nine species shows utility our approach.

10.1002/jcc.21501 article EN Journal of Computational Chemistry 2010-03-11

Although domesticated tomato is cultivated by wild tomato, there are a lot of differences between and such as shape, physiological function life history. Many studies show that has better salt resistance drought resistance. In addition to, tomato's fruit bigger more nutritious than tomato. The different features closely related to differentially expressed genes. We identified 126 up-regulated genes 87 down-regulated in RNA-Seq. These may be associated with resistance, nutrition. also further...

10.1371/journal.pone.0172411 article EN cc-by PLoS ONE 2017-03-09

Based on the concepts of cell and system graphical representation, a class 2D representations RNA secondary structures are given in terms classifications bases nucleic acids. The can completely avoid loss information associated with crossing overlapping corresponding curve. As an application, we make quantitative comparisons for set at 3'-terminus different viruses based representations. examination similarities/dissimilarities illustrates utility approach.

10.1002/jcc.20271 article EN Journal of Computational Chemistry 2005-07-14

On the basis of a class 2D graphical representations DNA sequences, sensitivity analysis has been performed, showing high-capability proposed to take into account small modifications sequences. And also indicates that absolute differences leading eigenvalues L/L matrices associated with increase number base mutations. Besides, we conclude similarity method based on correlation angles can better eliminate effects lengths sequences if compared using Euclidean distances. As application,...

10.1002/jcc.20922 article EN Journal of Computational Chemistry 2008-02-21

Sequence comparison is one of the foundations in bioinformatics, which can be used to study evolutionary relations among sequences. In this study, a 2D spectrum-like graphical representation protein sequences presented based on hydrophobicity scale amino acids. The frequencies amplitudes 4-subsequences are adopted characterize graph, and 17D vector as descriptor sequence. χ(2) value compatibility test performed. New similarity analysis approach illustrated all sequences, encoded by...

10.4137/ebo.s14713 article EN cc-by-nc Evolutionary Bioinformatics 2014-01-01

Subcellular localization prediction of protein is an important component bioinformatics, which has great importance for drug design and other applications. A multitude computational tools proteins subcellular location have been developed in the recent decades, however, existing methods differ sequence representation techniques classification algorithms adopted.In this paper, we firstly introduce two kinds sequences encoding schemes: dipeptide information with space Gapped k-mer information....

10.1186/s12859-019-3232-4 article EN cc-by BMC Bioinformatics 2019-12-01

ABSTRACT A novel erythrosine B derivative linked with a tertiary amine used as visible light initiator for free radical polymerization was synthesized and characterized. For comparison, the hydrophobic also its combination separated two component photoinitiator. The exhibited higher photoinitiator efficiency in high viscosity monomer than low one, compared counterpart. Especially, when it combined iodonium salt, further promotion of observed, three system. It found that salt together...

10.1002/app.42361 article EN Journal of Applied Polymer Science 2015-05-09

Background: As potent gene regulators, long noncoding RNAs (lncRNAs) are critical in various biological activities, such as cellular processes. With the development of new sequencing technologies, vast amount transcriptome data available, which require efficient computational tools to distinguish from their coding counterparts, especially for lncRNAs. Methods: In this paper, we review advancement methods predicting lncRNAs, summarize difficulties developing machine learning algorithms, and...

10.2174/1574893612666170905153933 article EN Current Bioinformatics 2017-09-06

ABSTRACT Three dye‐linked photoinitiators with excellent spectral stability in an acid medium were synthesized by the covalent bonding of a coinitiator (tertiary amine) and benzoyl group or two coinitiators to phenolic carboxyl position erythrosine B. The combination iodonium salt free tertiary amino used initiate free‐radical/cationic visible photopolymerization was investigated acquire relationship between structure performance. photoinitiating ability derivative bearing poorer than one...

10.1002/app.43035 article EN Journal of Applied Polymer Science 2015-11-20

Background Linc00312 is dysregulated in nasopharyngeal carcinoma (NPC) and participates the initiation progression of NPC. Our previous studies suggested that linc00312 was able to enhance sensitivity NPC cells irradiation patients with higher expression associated better short-term curative effect overall survival. The single nucleotide polymorphisms (SNPs) lncRNAs may influence disease course outcome by affecting expression, secondary structure or function lncRNAs. However, role SNPs on...

10.3389/fcell.2021.698558 article EN cc-by Frontiers in Cell and Developmental Biology 2021-07-16

Silk peptide used as a co‐initiator in type 2 photo‐initiator has not been known. In this study, the photoinitiation system is composed of sensitizer, synergist and silk with low molecular weight (<3,500), which to initiate photopolymerization common monomer. The same was performed evaluate co‐initiating ability four essential amino acids peptide, pentapeptides synthesized using them substrates, respectively. It suggested that glycine residue alanine on might be mainly responsible for...

10.1002/pen.24833 article EN Polymer Engineering and Science 2018-02-28

Eight visible photoinitiators composed of a series erythrosine B derivatives with different structures, combined ethyl-4-dimethylaminobenzoate and diphenyliodonium hexafluorophosphate, were evaluated for their photoinitiating characteristic the tensile properties photo-curing films initiated by them, to acquire relationship between structure performance. The photoinitiator was key component pigmented ink textile digital printing. So, based on experimental results, preferred incorporated into...

10.1177/0040517515621133 article EN Textile Research Journal 2015-12-17

A 2-D graphical representation of protein sequences based on two classifications amino acids is outlined. The method dividing a long sequence into k segments (SSM) introduced, so graph divided segments, geometrical center the points for all curve segment given as descriptors sequences. It not only useful comparative study proteins, but also encoding innate information about structure proteins. Finally, simple example taken to highlight behavior new descriptor from 12 baculoviruse

10.1109/isb.2012.6314157 article EN 2012-08-01
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