A5103121960- Ethnobotanical and Medicinal Plants Studies
- Natural Antidiabetic Agents Studies
- Phytochemistry and Biological Activities
- Medicinal Plants and Neuroprotection
- Pharmacological Effects of Natural Compounds
- Phytochemistry and Bioactivity Studies
- Phytochemistry and Bioactive Compounds
- Phytochemistry and biological activities of Ficus species
- Natural product bioactivities and synthesis
- Essential Oils and Antimicrobial Activity
- Drug-Induced Hepatotoxicity and Protection
- Advances in Cucurbitaceae Research
- Biochemical Analysis and Sensing Techniques
- Neuroscience and Neuropharmacology Research
- Alkaloids: synthesis and pharmacology
- Medicinal Plant Extracts Effects
- Hibiscus Plant Research Studies
- African Botany and Ecology Studies
- Cholinesterase and Neurodegenerative Diseases
- Bioactive Compounds and Antitumor Agents
- Biological Stains and Phytochemicals
- Medicinal Plant Research
- Herbal Medicine Research Studies
- Moringa oleifera research and applications
- Chemical synthesis and alkaloids
Bayero University Kano
2015-2024
Ahmadu Bello University
2008-2020
Bayer (France)
2020
Maitama Sule University Kano
2020
Securinega virosa is a commonly used medicinal plant in West Africa sub-region for the management of painful and inflammatory conditions. In present study, analgesic anti-inflammatory activities methanol root bark extract of S. virosa (SV) were investigated. The activity was evaluated using carrageenan-induced rat paw oedema while tested by acetic acid-induced writhing response hot plate tests Swiss albino mice, formalin-induced pain Wistar rats. methanolic SV (6.25 - 25 mg·kg-1 body weight,...
Cochlopermum tinctorium A. Rich.(Cochlospermaceae) is a commonly used medicinal plant in the West Africa sub-region for management of various conditions including pain and inflammatory conditions.In present study, we report analgesic anti-inflammatory activities aqueous methanol leaf (20-80 mg/kg), root (7.5-30 bark mg/kg) extracts plant.The potentials were studied using acetic acid induced writhing hot plate tests mice while activity was investigated carrageenan-induced paw edema rats.The...
Prosopis africana (Guill. & Perr.) Taub. (Mimosoideae) is a shrub used for menstrual and general body pain in Nupe land north central Nigeria. In this study, the methanol extract of stem bark (at doses 62.5, 125, 250 mg/kg) was evaluated analgesic anti-inflammatory activities using acetic acid-induced writhing assay carrageenan-induced inflammation rats. The significantly (P <0.05) attenuated with highest activity observed at dose, mg/kg (76.89%) comparable to that piroxicam (83.16%)...
Carissa edulis Vahl (Apocynaceae) is used in Nigerian folk medicine to manage a plethora of diseases including epilepsy, cancer, and inflammation; its efficacy widely acclaimed among communities northern Nigeria.This study establishes anticonvulsant activities aqueous fraction ethanol root bark extract (RAF) sub-fractions (S1 S2) animal models.We evaluated the acute toxicity RAF, S1 S2, activity using pentylenetetrazole (PTZ), picrotoxin, strychnine, N-methyl-d-aspartate (NMDA), isoniazid...
The methanol extract of the aerial parts Anisopus mannii was evaluated for its analgesic and antiinflammatory activities. effect studied using acetic acid-induced abdominal constriction test in mice, while anti-inflammatory investigated carrageenan induced paw oedema rats. results study showed that (40 mg/Kg) exhibited significant (P < 0.01) effect. It also at a dose 20 mg/kg. Phytochemical screening revealed presence alkaloids, flavonoids, saponins, steroids tannins. found to have an...
This study was undertaken to evaluate the hypoglycemic effect of methanol extract securinega virosa leaves on blood levels streptozocin-induced diabetes rats. Three doses (100, 300 and 600 mg/kg) were administered intraperitoneally. After 2 h administration there no significant change in glucose all three extract. Also after 4, 8 24 a (p The preliminary phytochemical screening revealed presence reducing sugars, cardiac glycosides, resin, tannins, saponins, flavonoids, glycerin carbohydrate,...
Schizophrenia is a highly disabling chronic psychiatric illness. The existing antipsychotic agents are associated with untoward effects and drug interactions leading to the intensification of search for newer better efficacy safety profile. Securinega virosa commonly used medicinal plant in African traditional medicine. decoction leaves combination other plants management mental In this study, we evaluate potential methanol leaf extract (25, 50 100 mg kg(-1)) using apomorphine-induced...
Malaria is an inflammatory cytokine driven disease that sometimes results in death due to lyses of red blood cells.The presents a major health challenge the world especially tropical and subtropical areas.The aim this research was evaluate modulation expression vivo antimalarial activity residual aqueous fraction (RAF) methanol leaf extract Ficus asperifolia (FaMLE).The dissolved distilled water serially partitioned with solvents different polarity obtain fraction.Standard protocol used...
Ficus asperifolia (Miq), family Moraceae is popularly known as sand-paper tree that found in marshy areas around river banks. In Nigeria, it called kawusa by Hausa tribe, ipin Yoruba tribe and asesa or amerenwa Igbo tribe. This research aims to quantify secondary metabolites present the crude methanol extract fractions characterize identified compounds residual aqueous fraction of leaves. The powdered fruit was extracted using 6L 70% methanol. dissolved water fractionated chloroform,...
Cissus cornifolia Baker - Planch (Family: Vitaceae) is used for various central nervous system disorders. The present study reported the sedative and depressant effects of fractions (butanol soluble portion its flavonoid rich fraction) obtained from methanolic leaf extract using diazepam induced sleep, head-dip motor coordination tests in mice at doses between 5 to 600 mg/kg body weight. column fraction 3 (CF3) significantly (p <0.05) prolonged duration sleep dose 10 20 mg/kg. Similarly,...