A5082490999- Renal Transplantation Outcomes and Treatments
- Organ Transplantation Techniques and Outcomes
- Hepatitis C virus research
- Organ Donation and Transplantation
- Transplantation: Methods and Outcomes
- Pharmacological Effects and Toxicity Studies
- Liver Disease Diagnosis and Treatment
- Dialysis and Renal Disease Management
- Family and Patient Care in Intensive Care Units
- Hepatitis B Virus Studies
- Respiratory Support and Mechanisms
- Emergency and Acute Care Studies
- Pediatric Urology and Nephrology Studies
- Pharmacogenetics and Drug Metabolism
- Hormonal and reproductive studies
- Metabolism and Genetic Disorders
- HIV/AIDS drug development and treatment
- Renal and Vascular Pathologies
Medical University of Warsaw
2017-2023
ENWEndNote BIBJabRef, Mendeley RISPapers, Reference Manager, RefWorks, Zotero AMA Warzyszyńska K, Jonas M, Wasiak D, Kosieradzki Małkowski P. Accelerated hepatocellular carcinoma recurrence rate after postoperative direct-acting antivirals treatment – preliminary report. Clinical and Experimental Hepatology. 2017;3(4):194-197. doi:10.5114/ceh.2017.71483. APA Warzyszyńska, K., Jonas, M., Wasiak, D., Kosieradzki, & Małkowski, (2017). Hepatology, 3(4), 194-197....
(1) Background: Only unbound tacrolimus particles are considered to be active and capable of crossing cellular membranes. Thus, the free-drug concentration might better associated with clinical effects than total drug used for dosage adjustment. We propose a new, fully validated online liquid chromatography-tandem mass spectrometry (LC-MS/MS) method measurement. (2) Methods: The determination in plasma ultrafiltrate was performed Nexera LC system LCMS-8050 triple quadrupole MS using...
Obese renal transplant recipients (body mass index [BMI] ≥30 kg/m2) are at risk of delayed graft function and postoperative complications, such as infections or wound healing. There is also a tendency to exclude extremely obese patients from transplantation (KTx). Nonetheless, no association between obesity increased mortality has been reported. The aim this study evaluate the effect BMI on most common surgical infectious complications after KTx.An observational in 872 transplanted 2010-2017...
Urinary tract infection (UTI) occurs in 21% of kidney recipients within the first 3 months after transplantation (KTx). It is associated with impaired graft function. Ureteral stent placement increases occurrence UTIs. The aim this study was to assess correlation between double-J placement, UTI incidence, and function.We conducted an observational 753 patients transplanted 2010 2017 compliance Helsinki Congress Istanbul Declaration. Recipients preserved function at 1-year follow-up were...
Introduction: Tacrolimus is metabolized mainly in the liver by CYP3A enzyme family, with a particularly well-documented role of CYP3A5. CYP3A5 also expressed renal tissue and present transplanted kidney. To date, association between donor polymorphisms transplant outcome remains poorly understood. The aim this study was to assess effect expression on early long-term outcomes. Methods: A retrospective cohort including 207 patients who received kidney grafts from 110 deceased donors conducted...
Previous reports have established that patient CYP3A5 allelic variability may be the most important genetic contributor to interindividual variation in tacrolimus exposure renal transplant recipients. However, protein is expressed allogenic kidney. The aim of this study was investigate role genotype concentration-to-dose ratio within 3 years posttransplant.A retrospective cohort 90 recipients and their donors evaluated effect single-nucleotide polymorphism (rs776746) on exposure. area under...
BACKGROUND After renal transplantation, immunosuppressants should be administered to prevent organ rejection and prolong graft survival. One of them is tacrolimus, which metabolized by the CYP3A enzyme family. The variability CYP3A5 gene in transplant recipients has been previously studied for its correlation with acute allogeneic kidney function. also present tissue, relevance not yet extensively investigated. This study aimed evaluate effect donor recipient expression status on early...
Introduction: Little is known about the quality of healthcare in intensive care units (ICUs) Poland. Data on patients hospitalized ICUs Warsaw and results their treatment are scarce. This information, crucial for improving ICU services, not collected routinely. Quality indicators essential concept holistic management. Implementation these a complex time-consuming process. Systematic increase demand assessment tools that can reflect real conditions practices ICUs, prompts search effective...