A5035758943- Cardiac Valve Diseases and Treatments
- Infective Endocarditis Diagnosis and Management
- Renal Transplantation Outcomes and Treatments
- Antiplatelet Therapy and Cardiovascular Diseases
- Coronary Interventions and Diagnostics
- Chronic Kidney Disease and Diabetes
- Organ Donation and Transplantation
- Hepatitis C virus research
- Venous Thromboembolism Diagnosis and Management
- Aortic Disease and Treatment Approaches
- COVID-19 and Mental Health
- Polyomavirus and related diseases
- Atrial Fibrillation Management and Outcomes
- Transplantation: Methods and Outcomes
- Organ Transplantation Techniques and Outcomes
- Healthcare professionals’ stress and burnout
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac Arrest and Resuscitation
- Acute Myocardial Infarction Research
- Health and Medical Research Impacts
- Animal Virus Infections Studies
- Complement system in diseases
- Bladder and Urothelial Cancer Treatments
- MicroRNA in disease regulation
- COVID-19 and healthcare impacts
Andrzej Frycz Modrzewski Krakow University
2020-2023
Medical University of Warsaw
2012-2023
Royal Brompton & Harefield NHS Foundation Trust
2020-2023
Government of the United Kingdom
2023
Royal Brompton Hospital
2023
Harefield Hospital
2020-2022
American Heart of Poland
2017-2022
Goethe University Frankfurt
2021
Medical University of Lodz
2021
Institute of Cardiology
2011-2017
Life-threatening complications occur during transcatheter aortic valve implantation (TAVI) which can require emergent cardiac surgery (ECS). Risks and outcomes of patients needing ECS or immediately after TAVI are still unclear.Incidence, risk factors, management, requiring transfemoral (TF)-TAVI were analysed from a contemporary real-world multicentre registry. Between 2013 2016, 27 760 underwent TF-TAVI in 79 centres. Of these, 212 (0.76%) required (age 82.4 ± 6.3 years, 67.5% females,...
Vascular complications are the main safety limitations of transcatheter aortic valve implantation (TAVI). The aim study was to assess incidents, predictors, and impact early vascular on prognosis after TAVI. This a single-center analysis related Early were defined as incidents within 30 days TAVI comprised transvascular: transfemoral/transsubclavian ,and transapical bioprosthesis implantation. Evaluated risk factors were: (1) clinical characteristics, (2) route, (3) center experience. In...
Cardiovascular disease is a model example of preventable condition for which practice guidelines are particularly important. In 2016, the joint task force created by European Society Cardiology (ESC) together with 10 other societies released new version on cardiovascular prevention. To facilitate implementation ESC guidelines, dedicated prevention committee has been established within Association Preventive Cardiology. The paper will first explore potential barriers to guidelines'...
Abstract Background COVID-19 has challenged the health system organization requiring a fast reorganization of diagnostic/therapeutic pathways for patients affected by time-dependent diseases such as acute coronary syndromes (ACS). Aim To describe ACS hospitalizations, management, and complication rate before after pandemic was declared. Design Ecological retrospective study. Methods: We analyzed aggregated epidemiological data all > 18 years old admitted in twenty-nine hub cardiac...
Abstract Aims Women’s participation is steadily growing in medical schools, but they are still not sufficiently represented cardiology, particularly cardiology leadership positions. We present the contemporary distribution of women leaders departments World Health Organization European region. Methods and results Between August December 2020, we applied purposive sampling to collect data analyse gender heads department university/third level hospitals 23 countries: Austria, Azerbaijan,...
Although infective endocarditis (IE) represents a unique model of thrombo-inflammatory disease, the most frequent early complications surgical valve replacement (SVR) in IE population are coagulopathy and bleeding. The hemostatic capacity procedure-related coagulation disorders patients undergoing SVR unknown. aims this study were to test periprocedural hemostasis urgent SVR, assess association between bleeding as well with thromboembolic events.A prospective, two-center, hypothesis...
I In nt tr ro od du uc ct ti io on n: : Dual antiplatelet therapy (DAPT) -aspirin and clopidogrel -is recommended after transcatheter aortic valve implantation (TAVI) without an evidence base.The main aim of the study was to estimate impact antithrombotic early late bleeding.Moreover, we assessed patients' characteristics bleeding influence prognosis.M Ma at te er ri ia al l a nd d m me et th ho ds s: Between 2009 2011, 83 consecutive TAVI patients, age 81.1 ±7.2 years, were...
Background: The risk of bleedings in transcatheter aortic valve implantation (TAVI) patients increases due to age and concomitant diseases. aim the study was assess bleedings, their influence on early prognosis TAVI utility TIMI GUSTO scales evaluation bleeding prediction blood transfusion. Methods: This a single center in-hospital 56 consecutive patients. Bleedings were classified according scales. HASBLED's scale factors, diabetes mellitus, female sex, route bioprosthesis inhospital...
Chronic renal allograft dysfunction (CAD) is a major limiting factor of long-term graft survival. The hallmarks progressive CAD are interstitial fibrosis and tubular atrophy (IFTA). MicroRNAs small, regulatory RNAs involved in many immunological processes. In particular, microRNA-21-5p (miR-21) considered to be strongly associated with pathogenesis regarding tubulointerstitium. aim this study was assess urinary miR-21 expression levels the kidney transplant recipients determine their...
Although the lungs are potentially highly susceptible to post-cardiac arrest syndrome injury, issue of acute respiratory failure after out-of-hospital cardiac has not been investigated. The objectives this analysis were determine prevalence arrest, its association with inflammatory response and clarify importance for early mortality.The Post-Cardiac Arrest Syndrome (PCAS) pilot study was a prospective, observational, six-centre project (Poland 2, Denmark 1, Spain Italy UK 1), studying...
The provision of high-quality education allows the European Society Cardiology (ESC) to achieve its mission better cardiovascular practice and provides an essential component translating new evidence improve outcomes.The 4th ESC Education Conference, held in Sophia Antipolis (December 2016), brought together leaders, National Directors Training 43 countries, representatives Young Community. Integrating national descriptions cardiology training, we discussed innovative pathways further...
Mini Chromosome Maintenance 5 (MCM5) is considered as a urinary biomarker of bladder cancer. ADXBLADDER commercially available test to detect MCM5 antibodies.External validation histopathologically confirmed non-muscle invasive cancer (NMIBC) recurrence.The study enrolled 119 consecutive patients with history NMIBC and 37 healthy volunteers matched controls. Single, full-void urine samples were collected from before cystoscopy ± TUR. To measure expression, Arquer Diagnostics was used. The...
(1) Background: Only unbound tacrolimus particles are considered to be active and capable of crossing cellular membranes. Thus, the free-drug concentration might better associated with clinical effects than total drug used for dosage adjustment. We propose a new, fully validated online liquid chromatography-tandem mass spectrometry (LC-MS/MS) method measurement. (2) Methods: The determination in plasma ultrafiltrate was performed Nexera LC system LCMS-8050 triple quadrupole MS using...
Background: The chronic kidney disease (CKD) population, including transplant recipients (KTRs) and subjects on renal replacement therapy, is particularly vulnerable to unfavorable outcomes from hepatitis C (CHC). Currently, there are oral direct-acting antiviral agents (DAAs) available eradicate the virus with favorable short-term outcomes; however, their long-term effects lacking. aim of study assess efficacy safety DAA therapy in CKD population. Methods: An observational, cohort...
Post-transplant antihuman leukocyte antigen donor-specific antibodies (anti-HLA DSAs) monitoring in kidney transplant recipients remains unclear and is currently under investigation. The pathogenicity of anti-HLA DSAs determined by antibody classes, specificity, mean fluorescent intensity (MFI), C1q-binding capacity, IgG subclasses. aim this study was to investigate the association circulating their characteristics with renal allograft long-term outcomes. included 108 consecutive patients...
It is an incompletely understood condition characterized clinically by a gradual deterioration of graft function, often associated with increasing proteinuria and arterial hypertension. 5 The main histological feature chronic allograft injury interstitial fibrosis tubular atrophy (IF/TA), which can be classified as mild, moderate, or severe (grade I, II, III) according to the Banff grading system. 6,7It was found that injury, fibrosis, in protocol biopsies are subclinical rejection....
The pandemic of Novel Coronavirus Disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has provoked hundreds thousands deaths, resulting in catastrophe for humans. Although some insights have been garnered studies on women, children and young adults infected with COVID-19, these often remain fragmented literature. Therefore, we discussed the impact COVID-19 patients, particularly those underlying cardiovascular comorbidities or congenital heart...
Background:An abdominoscrotal hydrocele (ASH) is a rare lesion and should be considered in the differential diagnosis of abdominal cystic lesions boys. Case Report:We report case 4-month-old boy with thin-walled, anechoic mass ultrasound (US) examination.As size increased follow-up US after one month, computed tomography (CT) was performed.CT demonstrated communication between abdomen right scrotal -an (ASH).The patient had no symptoms observed by means examination.After next 4 months, ASH...
Abstract Aims The implementation of the 2013 European Society Cardiology (ESC) Core Curriculum guidelines for acute cardiovascular care (acc) training among countries is unknown. We aimed to evaluate current status acc cardiology trainees and young cardiologists (<40 years) from ESC countries. Methods results survey (March–July 2019) asked about details training, self-confidence in technical non-technical skills, access opportunities, needs further field. Overall 614 doctors, 31...