A5024718373- Coronary Interventions and Diagnostics
- Cardiac Valve Diseases and Treatments
- Cardiac Imaging and Diagnostics
- Cerebrovascular and Carotid Artery Diseases
- Peripheral Artery Disease Management
- Acute Myocardial Infarction Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Aortic aneurysm repair treatments
- Cardiac pacing and defibrillation studies
- Infective Endocarditis Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Vascular Procedures and Complications
- COVID-19 and healthcare impacts
- Cardiac and Coronary Surgery Techniques
- Cardiac Health and Mental Health
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiovascular Disease and Adiposity
- Aortic Disease and Treatment Approaches
- Cardiac Ischemia and Reperfusion
- Renal and Vascular Pathologies
- Heart Failure Treatment and Management
- Health Systems, Economic Evaluations, Quality of Life
- Angiogenesis and VEGF in Cancer
- Cardiovascular Function and Risk Factors
- Venous Thromboembolism Diagnosis and Management
American Heart of Poland
2016-2025
Academy of Fine Arts in Katowice
2023-2025
Katowice School of Technology
2022-2024
Medical University of Silesia
2007-2024
Andrzej Frycz Modrzewski Krakow University
2020-2023
Gdańsk University of Technology
2023
Ospedale degli Infermi
2022
University of Silesia in Katowice
2022
Akademii Wychowania Fizycznego im. Jerzego Kukuczki w Katowicach
2018-2021
Rzeszów University of Technology
2020
We aimed to demonstrate that, by separating endothelial progenitor cell capture from sirolimus delivery through the application of drug abluminal surface stent, degree endothelialization can be enhanced.Stainless steel R Stents, with biodegradable SynBiosys polymer coating abluminally applied and modified anti-CD34 antibody were prepared at 2 dosages (low-dose [LD-Combo, 2.5 microg sirolimus/mm] full-dose [Combo, 5 sirolimus/mm). These Combo stents Cypher stent (10 sirolimus/mm) deployed in...
Extracellular matrix (ECM) remodeling contributes to in-stent restenosis and thrombosis. Despite its important clinical implications, little is known about ECM changes post-stent implantation.Bare-metal drug-eluting stents were implanted in pig coronary arteries with an overstretch under optical coherence tomography guidance. Stented segments harvested 1, 3, 7, 14, 28 days post-stenting for proteomics analysis of the media neointima.A total 151 ECM-associated proteins identified by mass...
Background— Drug-coated balloons are rapidly emerging as a therapeutic alternative for the interventional treatment of peripheral vascular disease. The purpose this study was to test hypothesis that an angioplasty balloon coated with mTOR inhibitor zotarolimus (ZCB) would inhibit neointimal hyperplasia in novel injury-based superficial femoral artery model familial hypercholesterolemic swine. Methods and Results— A total 44 swine were included (12 designated tissue pharmacokinetics 32 safety...
Although optical coherence tomography (OCT) is capable to detect microscopic peri-strut changes that seem be related neointimal inhibition and healing, its ability characterize these components still limited. In this study, we aimed compare different OCT morphological characteristics with in-stent tissue types analysed by histology. A total of 69 stents (39 drug eluting 30 bare metal stents) were implanted in coronary arteries 27 swine. By OCT, type was classified as homogeneous,...
The aim of the pilot SECRITT trial was to evaluate safety and feasibility sealing high risk IVUS optical coherence tomography-derived thin cap fibroatheroma (TCFA), with a dedicated nitinol self-expanding vShield device.After screening angiography, fractional flow reserve (FFR), intravascular ultrasound virtual histology (IVUS-VH) tomography (OCT), 23 patients met enrolment criteria (presence non-obstructive VH-derived TCFA lesion on OCT) were randomised (n=13) versus medical therapy (n=10)....
The number of patients with heart failure (HF) and implantable cardiac electronic devices has been growing steadily. Remote monitoring care (RC) can facilitate patient-healthcare clinical interactions prompt preventive activities to improve HF outcomes. However, studies that have investigated the efficacy remote shown mixed findings, better results for system including daily verification transmission. purpose RESULT study was analyse impact on outcomes in cardioverter-defibrillator...
Myocardial infarction with nonobstructive coronary arteries (MINOCA) constitutes 3–15% of all acute myocardial infarctions. Women are more frequently diagnosed MINOCA, although the influence sex on long-term outcomes is still unclear. In this study we aimed to compare sex-based differences in baseline characteristics and clinical patients suspected MINOCA. We have retrospectively analyzed 6063 MINOCA (3220 females 2843 male patients) from combined 3 large polish registries (PL-ACS, SILCARD...
Background: Cardiogenic shock (CS) remains the leading cause of poor prognosis in patients with acute myocardial infarction (AMI), sustaining a high mortality rate 40 to 50% within 30 days. Aims: In this unique analysis two national all-comers, real-life registries including AMI complicated by CS, for whom early revascularization was planned, we aimed compare effect percutaneous coronary (PCI) and artery bypass grafting (CABG) on 30-day 1-year all-cause mortality. Methods: The study included...
Postconditioning and cyclosporine A prevent mitochondrial permeability transition pore opening providing cardioprotection during ischemia/reperfusion. Whether microvascular obstruction is affected by these interventions largely unknown. Pigs subjected to coronary occlusion for 1 h followed 3 of reperfusion were assigned control (n = 8), postconditioning 9) or intravenous infusion 10–15 min before the end ischemia 8). was induced 8 cycles repeated 30-s balloon inflation deflation. After...
Background: Diagnosis of myocardial infarction with non-obstructive coronary arteries (MINOCA) requires both clinical evidence acute (AMI) and demonstration using angiography. We compared the features, treatments, three-year outcomes in patients MINOCA obstructive artery disease (MI-CAD). Methods: retrospectively analyzed data for 205,606 hospitalized AMI. was indicated as a working diagnosis 6063 (2.94% all AMI patients). For control group we included 160,886 MI-CAD. evaluated baseline...
Advances in the acute treatment of myocardial infarction (AMI) substantially reduced in-hospital mortality, but post-discharge prognosis is still unacceptable. The Managed Care Acute Myocardial Infarction (MC-AMI) a program Poland's National Health Fund that aims at comprehensive post-AMI care to improve long-term prognosis. aim study was assess effect MC-AMI on all-cause mortality one-year follow-up.MC-AMI includes MI treatment, complex revascularization, cardiac rehabilitation (CR),...
Background: Numerous randomized clinical trials have demonstrated the superiority of thin-strut biodegradable polymer second-generation drug-eluting stent to first-generation and noninferiority permanent stent. Data on long-term outcomes with a novel ultrathin stent, date, are limited. Methods: The DESSOLVE III trial (Multicenter Randomized Study MiStent Sirolimus Eluting Absorbable Polymer Stent System for Revascularization Coronary Arteries; n=1398) is prospective, multicenter,...
The aim of this study was to evaluate the safety and efficacy BioMime sirolimus-eluting coronary stent (SES) compared XIENCE family everolimus-eluting stents (EES) in treatment patients with de novo native artery lesions.The meriT-V is a prospective, multicentre, randomised, open-label, active-controlled, non-inferiority trial. A total 256 up two lesions were enrolled randomly assigned (2:1) SES or EES. non-inferior EES for primary endpoint in-stent late lumen loss (0.15±0.27 mm vs....
The collateral damage caused by the COVID-19 pandemic affected cardiovascular disease patients, mainly acute coronary syndrome (ACS) cases. Additionally, lockdown treatment-related concerns and reluctance to seek medical help, factors that can delay treatment.We aimed analyze incidence course of ACS after first wave.The report is based on a multi-institutional registry 10 interventional cardiology departments. patient data were gathered from June October 2020, i.e. in period following Poland...
Abstract Objectives: The purpose of the present study was to evaluate efficacy and safety a biodegradable polymer coated, paclitaxel eluting stent (Luc‐Chopin 2 ) based on 9‐months angiographic 12‐months clinical follow‐up results. Background: First‐generation drug‐eluting stents utilize nonbioabsorbable polymeric coatings, whose persistent presence in arterial wall may negatively affect long‐term outcomes. Bioabsorbable coatings with degradation period matched that drug elution be better...