A5031681358- Prostate Cancer Diagnosis and Treatment
- Prostate Cancer Treatment and Research
- Urologic and reproductive health conditions
- Microbial Inactivation Methods
- Urological Disorders and Treatments
- Urinary and Genital Oncology Studies
- Radiomics and Machine Learning in Medical Imaging
- Bladder and Urothelial Cancer Treatments
- Renal cell carcinoma treatment
- Genital Health and Disease
- Ureteral procedures and complications
- Adrenal and Paraganglionic Tumors
- Pediatric Urology and Nephrology Studies
- Urinary Bladder and Prostate Research
- Synthesis and biological activity
- Renal and Vascular Pathologies
- MRI in cancer diagnosis
- Ultrasound and Hyperthermia Applications
- Cancer Research and Treatments
- Reconstructive Surgery and Microvascular Techniques
- Cardiac Imaging and Diagnostics
- Artificial Intelligence in Healthcare and Education
- Radiopharmaceutical Chemistry and Applications
- Colorectal and Anal Carcinomas
- Radiation Effects and Dosimetry
Royal Brisbane and Women's Hospital
2021-2024
Sheffield Teaching Hospitals NHS Foundation Trust
2024
Garvan Institute of Medical Research
2016-2022
Toowoomba Hospital
2018-2022
Ipswich Hospital
2020
The Kinghorn Cancer Centre
2016-2019
UNSW Sydney
2016-2018
Prostate Cancer Foundation of Australia
2017-2018
Princess Alexandra Hospital
2018
St Vincent's Clinic
2017
Objective To evaluate the ability of prostate‐specific membrane antigen ( PSMA )‐positron‐emission tomography PET )/computed CT ) to detect intermediate‐grade intra‐prostatic prostate cancer PC a), and determine if ‐ improves diagnostic accuracy multiparametric magnetic resonance imaging (mp MRI ). Patients Methods A total 56 consecutive patients with International Society Urological Pathology ISUP grade 2–3 a after radical prostatectomy, who underwent both mp (hereafter preoperatively, were...
Objectives To determine the safety, quality of life (QoL) and short‐term oncological outcomes primary focal irreversible electroporation ( IRE ) for treatment localized prostate cancer PC a), to identify potential risk factors failure. Patients Methods who met consensus guidelines on patient criteria selection methods therapy were eligible analysis. Focal was performed organ‐confined clinically significant a, defined as high‐volume disease with Gleason sum score 6 (International Society...
Different nomograms exist for the preoperative prediction of pelvic lymph-node metastatic disease in individual patients with prostate cancer (PCa). These do not incorporate modern imaging techniques such as prostate-specific membrane antigen (PSMA) positron emission tomography (PET).To determine predictive performance Briganti 2017, Memorial Sloan Kettering Cancer Center (MSKCC), and 2019 addition PSMA-PET an international, multicenter, present-day cohort undergoing robot-assisted radical...
The objective of this study was to evaluate the safety and feasibility 99mTc-based prostate-specific membrane antigen (PSMA) robot-assisted-radioguided surgery aid or improve intraoperative detection lymph node metastases during primary robot-assisted radical prostatectomy (RARP) for prostate cancer (PCa). Methods: Men with high-risk PCa (≥ cT3a, International Society Urological Pathology (ISUP) grade group ≥ 3 15 ng/mL) potential metastasis (Briganti nomogram risk > 10% on preoperative...
Preoperative assessment of the probability pelvic lymph-node metastatic disease (pN1) is required to identify patients with prostate cancer (PCa) who are candidates for extended dissection (ePLND).
Objectives To evaluate the safety and short‐term oncological outcomes of 68 gallium‐labelled prostate‐specific membrane antigen ( Ga‐ PSMA ) positron‐emission tomography PET )/computed CT )‐directed robot‐assisted salvage node dissection RASND for prostate cancer oligometastatic nodal recurrence. Materials Methods Between February 2014 April 2016, 35 patients across two centres underwent / ‐detected was performed using targeted pelvic dissection, unilateral extended template or bilateral...
Objectives To evaluate the feasibility, safety, early quality‐of‐life (QoL) and oncological outcomes of salvage focal irreversible electroporation ( IRE ) for radio‐recurrent prostate cancer PC a). Patients Methods with localized, a without evidence metastatic or nodal disease were offered according to consensus guidelines. minimum follow‐up 6 months eligible analysis. Adverse events monitored using National Cancer Institute Common Terminology Criteria Events CTCAE version 4.0)....
The design, conduct and completion of randomized trials for curative prostate cancer (PCa) treatments are challenging. To evaluate the effect robot-assisted radical prostatectomy (RARP) versus focal irreversible electroporation (IRE) on patient-reported quality life (QoL) early oncological control using propensity-scored matching.Patients with T1c-cT2b significant PCa (high-volume ISUP 1 or any 2/3) who received unifocal IRE were pair-matched to patients nerve-sparing RARP. Patient-reported...
We aimed to evaluate the genitourinary function and quality of life (QoL) following ablation different prostate segments with irreversible electroporation (IRE) for localized cancer (PCa).Sixty patients who received primary focal IRE organ-confined PCa were recruited this study. Patients evaluated QoL per segment treated (anterior vs. posterior, apex base apex-to-base, unilateral bilateral). system settings patient characteristics compared between preserved those impaired erectile urinary...
Lichen sclerosus (LS) in men commonly involves the external genitalia, with up to 20% of these patients developing urethral stricture disease, and a small group malignant transformation penile squamous cell carcinoma (SCC). The objective this study was determine prevalence LS its sequelae males presenting for circumcision.A multicentre retrospective cohort conducted at 8 hospitals within 3 Australian regional centres. We identified who underwent circumcision between January 2004 November...
To assess whether completeness of pelvic lymph node dissection (PLND) as measured by yield reduces biochemical recurrence (BCR) in men undergoing radical prostatectomy (RP) for prostate cancer (PCa), stratified according to Briganti nomogram-derived risk (≥5% vs. < 5%) invasion (LNI).Retrospective study 3724 who underwent RP between January 1995 and 2015 from our prospectively collected institutional database. All included had minimum five years follow-up were not given androgen deprivation...
Radical cystectomy can be a morbid operation [...]
Artificial intelligence (AI) in urology is evolving and has rapidly expanded since the release of ChatGPT other large language models (LLMs). Early studies have found that AI-generated patient information moderate to high quality for questions across multiple uro-oncology domains.1 Extension into clinical decision-making suggests can make decisions aligned with evidence-based medicine.2 The key limitation publicly available (version 3.5) been a reliance on knowledge confined data published...
Introduction. To assess the performance of five previously described clinicopathological definitions low-risk prostate cancer (PC). Materials and Methods. Men who underwent radical prostatectomy (RP) for clinical stage ≤T2, PSA <10 ng/mL, Gleason score <8 PC, diagnosed by transperineal template-guided saturation biopsy were included. The criteria (i.e., 1-5, criterion 1 stringent (Gleason 6 + ≤5 mm total max core length PC ≤3 per PC) up to 5 less 6-7 with ≤5% grade 4) was analysed ability...
Primary sarcomatoid urothelial carcinoma of the ureter with heterologous elements is rare and carries a poor prognosis. Although there some literature on primary bladder carcinoma, ureteric involvement has been reported infrequently, this case report describes unusual histological finding concurrent divergent squamous differentiation. Despite laparoscopic radical nephroureterectomy, our patient died within six months diagnosis local recurrence metastatic spread. A more thorough understanding...
This case demonstrates the use of 123 I-MIBG scintigraphy in diagnosis testicular adrenal rest tumours (TART) an adult with classical congenital hyperplasia (CAH). TART are common CAH patients, MIBG scanning offering a new imaging modality to potentially help verify and prevent invasive investigation. Level evidence: 5 report
You have accessJournal of UrologyProstate Cancer: Localized: Surgical Therapy VII1 Apr 2016MP80-16 PREDICTING LOW-RISK PROSTATE CANCER FROM TRANSPERINEAL SATURATION BIOPSIES Amila Siriwardana, Pim van Leeuwen, Monique Roobol, Francis Ting, Daan Nieboer, James Thompson, Warick Delprado, Anne-Maree Haynes, Phillip Brenner, and Stricker SiriwardanaAmila Siriwardana More articles by this author , LeeuwenPim Leeuwen RoobolMonique Roobol TingFrancis Ting NieboerDaan Nieboer ThompsonJames Thompson...
Leiomyomas are smooth muscle tumours that rarely found in the kidney. There is one report of a leiomyoma kidney transplant paediatric recipient. Here, we an adult renal recipient who developed Epstein-Barr virus-positive his allograft 15 years after transplantation. The patient was converted to everolimus for posttransplant immunosuppression management and there no sign progression over year.