A5068689566- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Advanced MRI Techniques and Applications
- Acute Myocardial Infarction Research
- Cardiovascular Function and Risk Factors
- Cardiovascular Disease and Adiposity
- Cardiac pacing and defibrillation studies
- Cardiac Arrhythmias and Treatments
- Lung Cancer Treatments and Mutations
- Lung Cancer Diagnosis and Treatment
- Geriatric Care and Nursing Homes
- Health Systems, Economic Evaluations, Quality of Life
- Advanced Queuing Theory Analysis
- Advanced X-ray and CT Imaging
- Child and Adolescent Psychosocial and Emotional Development
- Cardiac Structural Anomalies and Repair
- Radiomics and Machine Learning in Medical Imaging
- Wireless Networks and Protocols
- Cardiac electrophysiology and arrhythmias
- Atrial Fibrillation Management and Outcomes
- Colorectal Cancer Treatments and Studies
- Mobile Ad Hoc Networks
- Dementia and Cognitive Impairment Research
- Spondyloarthritis Studies and Treatments
- Healthcare Operations and Scheduling Optimization
Amsterdam University Medical Centers
2018-2024
Vrije Universiteit Amsterdam
2011-2024
University Medical Center Utrecht
2022-2024
Heidelberg University
2023-2024
University Hospital Heidelberg
2023-2024
Utrecht University
2023-2024
Wilhelmina Children's Hospital
2022-2023
University of Utah
2022
Amsterdam Neuroscience
2022
Emma Kinderziekenhuis
2022
Ischemic heart disease is a major cause of out-of-hospital cardiac arrest. The role immediate coronary angiography and percutaneous intervention (PCI) in the treatment patients who have been successfully resuscitated after arrest absence ST-segment elevation myocardial infarction (STEMI) remains uncertain.
At present, the choice of noninvasive testing for a diagnosis significant coronary artery disease (CAD) is ambiguous, but nuclear myocardial perfusion imaging with single-photon emission tomography (SPECT) or positron (PET) and computed angiography (CCTA) predominantly used this purpose. However, to date, prospective head-to-head studies are lacking regarding diagnostic accuracy these modalities. Furthermore, combination anatomical functional assessments configuring hybrid approach may yield...
There is ambiguity whether frail patients with atrial fibrillation managed vitamin K antagonists (VKAs) should be switched to a non-vitamin oral anticoagulant (NOAC). We conducted pragmatic, multicenter, open-label, randomized controlled superiority trial. Older living frailty (≥75 years of age plus Groningen Frailty Indicator score ≥3) were randomly assigned switch from international normalized ratio-guided VKA treatment an NOAC or continued treatment. Patients glomerular filtration rate...
An increasing number of retail energy markets show price fluctuations, providing users with the opportunity to buy at lower than average prices. We propose temporarily store this inexpensive in a battery, and use it satisfy demand when prices are high, thus allowing exploit variations without having shift their low-price periods. study battery control policy that yields best performance, i.e., minimizes total discounted costs. The optimal is shown have threshold structure, we derive these...
Personality influences decision making and ethical considerations. Its influence on the occurrence of research misbehavior has never been studied. This study aims to determine association between personality traits self-reported questionable practices misconduct. We hypothesized that narcissistic, Machiavellianistic psychopathic as well self-esteem are associated with misbehavior.Included in this cross-sectional design were 535 Dutch biomedical scientists (response rate 65%) from all...
Percutaneous coronary intervention (PCI) of nonculprit vessels among patients with ST-segment elevation myocardial infarction (STEMI) is associated improved clinical outcome compared culprit vessel-only PCI. Fractional flow reserve (FFR) and are hyperemic indices used to guide revascularization. Recently, instantaneous wave-free ratio was introduced as a nonhyperemic alternative FFR. Whether these can be in the acute setting STEMI continues investigated.To assess value hemodynamic from index...
Abstract In human papillomavirus (HPV) cervical cancer screening, cytology is used as triage to counter the low specificity of HPV testing. VALID‐SCREEN a EU‐multicenter, retrospective study conducted evaluate clinical performance FAM19A4/miR124‐2 methylation‐based molecular test substitute or addition reflex testing screen positive women. methylation (QIAsure Methylation Test) was evaluated in 2384 HPV‐positive screening samples, from women 29‐76 years age, derived four EU countries....
Abstract Background Little RSV activity was observed during the first expected season since COVID‐19 pandemic. Multiple countries later experienced out‐of‐season resurgences, yet their association with non‐pharmaceutical interventions (NPIs) is unclear. This study aimed to describe changes in epidemiology pandemic and estimate between individual NPIs resurgences. Methods from Week (W)12‐2020 W44‐2021 compared three pre‐pandemic seasons using surveillance data Brazil, Canada, Chile, France,...
Different nomograms exist for the preoperative prediction of pelvic lymph-node metastatic disease in individual patients with prostate cancer (PCa). These do not incorporate modern imaging techniques such as prostate-specific membrane antigen (PSMA) positron emission tomography (PET).To determine predictive performance Briganti 2017, Memorial Sloan Kettering Cancer Center (MSKCC), and 2019 addition PSMA-PET an international, multicenter, present-day cohort undergoing robot-assisted radical...
The diagnostic performance of non-invasive imaging in patients with prior coronary artery disease (CAD) has not been tested prospective head-to-head comparative studies. aim this study was to compare the qualitative single-photon emission computed tomography (SPECT), quantitative positron (PET), and magnetic resonance (MRI) a myocardial infarction (MI) or percutaneous intervention (PCI).In clinical study, all MI and/or PCI new symptoms ischaemic CAD underwent 99mTc-tetrofosmin SPECT,...
To evaluate the feasibility and repeatability of various metabolically active tumor volume ( MATV ) quantification methods in fluorine 18 fluorodeoxyglucose FDG positron emission tomography (PET)/computed (CT) a multicenter setting propose optimal method together with minimal threshold for future response evaluation studies.The study was approved by institutional review board all four participating centers, patients provided written informed consent. Thirty-four advanced gastrointestinal...
Background Family caregivers of dementia patients are at increased risk developing depression or anxiety. A multi-component program designed to mobilize support family networks demonstrated effectiveness in decreasing depressive symptoms caregivers. However, the impact an intervention consisting solely meetings on and anxiety has not yet been evaluated. This study examines preventive effects for primary community-dwelling patients. Methods randomized multicenter trial was conducted among 192...
A rapidly growing number of oral anticancer agents has become available in oncology and hematology. Though these introductions have several benefits, medication adherence is an issue concern. Little known about the factors influencing to treatment with daily practice. Material methods. In this observational, multicenter study including 216 patients, carried out between October 2010 March 2012, use drugs was assessed by means a telephonic pill count, questionnaire review patient's medical...
Background Blood cultures remain the gold standard for detecting bacteremia despite their limitations. The current practice of blood culture collection is still inefficient with low yields. Limited focus has been given to association between timing specimen at different time points during admission and yield. Methods We carried out a retrospective observational study by analyzing all 3,890 sets collected from 1,962 admitted patients over seven-month period this study. compared yield early...
Abstract Aims Continuous thermodilution is a novel technique to quantify absolute coronary flow and microvascular resistance (MVR). Notably, intracoronary infusion of saline elicits maximal hyperaemia, obviating the need for adenosine. The primary aim this study was validate continuous in humans by comparing invasive measurements [15O]H2O positron emission tomography (PET). As secondary goal, MVR were compared between obtained with without Methods results Twenty-five patients underwent...
This work aims to gain insight into the long-term impact of depression course on social network size and perceived loneliness in older people living community.Within a large representative sample community (Longitudinal Aging Study Amsterdam (LASA)), participants with clinically relevant levels depressive symptoms (scores >16 Center for Epidemiological Studies Depression Scale) were followed up over period 13 years LASA study (five waves). General estimating equations used estimate...
Abstract Aims To evaluate the prognostic value of global and regional quantitative [15O]H2O positron emission tomography (PET) perfusion. Methods results In this retrospective study, 648 patients with suspected or known coronary artery disease (CAD) who underwent PET were followed for occurrence death myocardial infarction (MI). Global hyperaemic blood flow (hMBF) reserve (CFR) obtained from PET. During median follow-up 6.9 (5.0–7.9) years, 64 (9.9%) experienced composite (36–5.6%) MI...