A5050432568- Cardiac Imaging and Diagnostics
- Coronary Interventions and Diagnostics
- Advanced MRI Techniques and Applications
- Acute Myocardial Infarction Research
- Cardiac and Coronary Surgery Techniques
- Advanced X-ray and CT Imaging
- Cardiac Valve Diseases and Treatments
- Cardiovascular Disease and Adiposity
- Medical Imaging Techniques and Applications
- Cardiovascular Function and Risk Factors
- Cardiac electrophysiology and arrhythmias
- Cerebrovascular and Carotid Artery Diseases
- Vascular Procedures and Complications
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Mechanical Circulatory Support Devices
- Tattoo and Body Piercing Complications
- Aortic aneurysm repair treatments
- Peripheral Artery Disease Management
- Dermatologic Treatments and Research
- Nitric Oxide and Endothelin Effects
- Antiplatelet Therapy and Cardiovascular Diseases
- Radiation Dose and Imaging
- Ultrasound and Hyperthermia Applications
- Photoacoustic and Ultrasonic Imaging
- Cardiac, Anesthesia and Surgical Outcomes
Vrije Universiteit Amsterdam
2019-2025
Amsterdam University Medical Centers
2019-2025
Amsterdam UMC Location Vrije Universiteit Amsterdam
2021-2022
Hospital de Sant Pau
2021
Amsterdam UMC Location University of Amsterdam
2015-2019
University of Amsterdam
2015-2018
The recent development of artificial intelligence–guided quantitative coronary computed tomography angiography (CCTA) analysis (AI-QCT) has enabled rapid atherosclerotic plaque burden and characteristics. This study set out to investigate the 10-year prognostic value derived from AI-QCT compare spectrum manually assessed CCTA, artery calcium scoring (CACS), clinical risk was a long-term follow-up 536 patients referred for suspected disease. CCTA scans were analyzed with classified staging...
Noninvasive stress testing is commonly used for detection of coronary ischemia but possesses variable accuracy and may result in excessive health care costs. This study aimed to derive validate an artificial intelligence-guided quantitative computed tomography angiography (AI-QCT) model the diagnosis that integrates atherosclerosis vascular morphology measures (AI-QCTISCHEMIA) evaluate its prognostic utility major adverse cardiovascular events (MACE). A post hoc analysis CREDENCE (Computed...
Same-day discharge (SDD) in patients undergoing percutaneous coronary intervention (PCI) of a chronic total occlusion (CTO) is appealing because the increased patient comfort. However, data on SDD following large-bore vascular access are scarce.
Aims: This study aimed to evaluate associations between coronary collaterals and myocardial viability as assessed by quantitative cardiac magnetic resonance (CMR) imaging in patients with a chronic total occlusion (CTO). Methods results: A of 218 CTO who underwent CMR 2013 2018 were included. concomitant collateral connection (CC) score 2 Rentrop grade 3 defined well-developed 146 (67%) patients, whereas lower CC scores or grades characterised poorly developed collaterals. Dysfunctional...
Background Visual assessment of coronary CT angiography (CCTA) is time-consuming, influenced by reader experience and prone to interobserver variability. This study evaluated a novel algorithm for stenosis quantification (atherosclerosis imaging quantitative CT, AI-QCT). Methods The included 208 patients with suspected artery disease (CAD) undergoing CCTA in Perfusion Imaging Coronary Angiography With Invasive Angiography-1. AI-QCT blinded readers assessed following the Artery Disease...
ABSTRACT Background Revascularization decision‐making for saphenous vein grafts (SVGs) relies on angiographic lesion severity estimation, as studies fractional flow reserve (FFR) detecting ischemia in SVGs are scarce. Aims To compare FFR and quantitative coronary angiography (QCA) of against myocardial perfusion imaging (MPI) to establish an optimal threshold SVGs. Methods This cross‐sectional registry study included symptomatic patients with prior artery bypass grafting who underwent...
ABSTRACT Background The relationship between height differences related to graft anatomy and physiological pressure indices in coronary bypass grafts has not been studied. We sought study the impact of hydrostatic on fractional flow reserve (FFR) saphenous vein (SVGs). Methods Included were 66 symptomatic patients (76 SVGs) with prior artery grafting who underwent computed tomography angiography (CCTA) preceding invasive FFR interrogation ≥ 1 SVGs. course excursion reconstructed based CCTA...
Percutaneous coronary intervention (PCI) of chronic total occlusions (CTOs) typically involves extensive drug-eluting stent (DES) implantation. As a result, patients undergoing CTO PCI are exposed to relatively high risk in-stent restenosis and target lesion revascularization. While the application drug-coated balloons (DCBs) may improve patient outcome by reducing burden, randomized controlled trials investigating use DCB in lacking. The Co-CTO trial (NCT04881812) is single-blind,...
Currently, cutoffs of quantitative [
Abstract Objectives This study aimed to investigate the performance of computed tomography derived fractional flow reserve based interactive planner (FFR CT planner) predict physiological benefits percutaneous coronary intervention (PCI) as defined by invasive post‐PCI FFR. Background Advances in FFR technology have enabled simulation hyperemic pressure changes after virtual removal stenoses. Methods In 56 patients (63 vessels) measurements before and PCI were obtained was calculated using...
Coronary flow capacity (CFC) integrates quantitative hyperaemic myocardial blood (hMBF) and coronary reserve (CFR) to comprehensively assess physiological severity of artery disease (CAD). This study evaluated the effects revascularization on CFC as assessed by serial [15O]H2O positron emission tomography (PET) perfusion imaging.A total 314 patients with stable CAD underwent PET imaging at baseline after changes in hMBF, CFR, 415 revascularized vessels. Using thresholds for ischaemia normal...
Abstract Aims In chronic coronary syndrome (CCS) patients with documented artery disease (CAD), ischaemia detection by myocardial perfusion imaging (MPI) and an invasive approach are viable diagnostic strategies. We compared the performance of quantitative flow ratio (QFR) single-photon emission computed tomography (SPECT), positron (PET), cardiac magnetic resonance (CMR) in prior CAD [previous percutaneous intervention (PCI) and/or infarction (MI)]. Methods results This PACIFIC-2 sub-study...
In patients evaluated for obstructive coronary artery disease (CAD), guidelines recommend using either fractional flow reserve (FFR) or instantaneous wave-free ratio (iFR) to guide revascularization decision-making. The hemodynamic significance of lesions with discordant FFR and iFR measurements is debated. This study compared [<sup>15</sup>O]H<sub>2</sub>O PET–derived absolute myocardial perfusion between vessels concordant measurements. <b>Methods:</b> We included 197 suspected CAD who had...
Abstract Purpose To compare cardiac magnetic resonance imaging (CMR) with [ 15 O]H 2 O positron emission tomography (PET) for quantification of absolute myocardial blood flow (MBF) and reserve (MFR) in patients coronary artery disease (CAD). Methods Fifty-nine stable CAD underwent CMR PET. The protocol included late gadolinium enhancement to rule out presence scar tissue perfusion using a dual sequence, single bolus technique. Absolute MBF was determined the three main vascular territories...
Abstract Aims Myocardial ischaemic burden (IB) is used for the risk stratification of patients with coronary artery disease (CAD). This study sought to define a prognostic threshold quantitative [15O]H2O positron emission tomography (PET)-derived IB. Methods and results A total 623 suspected or known CAD who underwent PET perfusion imaging were included. The endpoint was composite death non-fatal myocardial infarction (MI). hyperaemic blood flow (hMBF) reserve (MFR)-derived IB determined....