Proposing a scoring tool to predict COVID-19 patients' outcomes based on initially assessed clinical and CT features.All patients, who were referred tertiary-university hospital respiratory triage (March 27-April 26, 2020), highly clinically suggestive for had undergone chest scan included. Those with positive rRT-PCR or suspicious patients typical pulmonary manifestations considered confirmed additional analyses. Patients, outcome, categorized into outpatient, ordinary-ward admitted,...

Abstract The diagnosis of cryptogenic liver disease is made when after extensive evaluations, recognizable etiologies chronic are excluded. In this study, the presence hepatitis C virus (HCV) RNA was tested in peripheral blood mononuclear cells (PBMCs) taken from Iranian patients who although were found negative for plasma HCV and anti‐HCV antibodies, suffered unknown etiology. From September 2007 to March 2010, 69 Tehran with etiology referred our center enrolled present study. PBMCs...

Background: Occult hepatitis C virus (HCV) infection is a new entity described by the presence of HCV-RNA in liver biopsy and/or peripheral blood mononuclear cell (PBMC) specimens, and undetectable levels or absence anti HCV antibodies plasma current laboratory methods. Objectives: To evaluate detection PBMC specimens transplant candidates with cryptogenic cirrhosis reverse transcriptase-nested polymerase chain reaction (RT-nested PCR). Patients Methods: From November 2007 to March 2013, 45...

Fatigue is common in primary biliary cirrhosis (PBC). Altered central serotonergic neurotransmission may be involved its pathogenesis. This multicenter, randomized, double-blind, placebo-controlled, crossover trial evaluated the efficacy of ondansetron, a selective 5-HT3 receptor subtype antagonist, for treating fatigue PBC. A design was chosen, allowing subjects to serve as their own controls—appropriate evaluate fatigue, subjective symptom. Sixty patients with clinically stable PBC,...

Liver transplantation is the global treatment of end-stage liver diseases. Since patients' survival rate has been improved, patient may experience reductions in physical, cognitive, and psychosocial functions after influencing their adherence to care treatment. The transplant complex should be considered when health providers make decisions regarding This qualitative study aimed explore factors self-management among recipients treatment.In this study, 23 interview sessions were carried out...

Background Percutaneous sclerotherapy with bleomycin has been proven to have a potential benefit in the management of low-flow venous malformations. Liver hemangiomas are considered Thus, percutaneous could potentially promising result their management. Purpose To investigate feasibility, efficacy, and safety symptomatic giant liver hemangioma (GLH). Materials Methods This single-institute prospective study was conducted between September 2018 July 2020. performed using mixture ethiodized...

Background: Hemangioma, a congenital vascular malformation, is the most common benign liver lesion that usually remain stable subsequently requiring not treatment; however, complications such as abdominal pain or fullness, coagulation disturbances, and inflammatory syndrome may occur, demanding specific treatment of hemangioma. Objectives: To assess safety, feasibility efficacy trans-catheter arterial embolization (TAE) for Liver hemangioma Patients Methods: TAE was performed on 20 patients...

OBJECTIVES Length of stay is considered an important surrogate for transplant survival rate and resource utilization. Therefore, in the present study, our aim was to determine factors affecting length hospital stay. MATERIALS AND METHODS We retrospectively analyzed records patients who underwent liver at Tehran University Medical Sciences Liver Transplantation Center from March 2014 2016. RESULTS For final analyses, there were 161 adult recipients, including 106 males (65.8%) 55 females...

PurposeThe current study aimed to evaluate the efficiency of dynamic contrast-enhanced (DCE) MRI visual features in classifying benign liver nodules and hepatocellular carcinoma (HCC) using a machine learning model.Methods115 LI-RADS3, 137 LI-RADS4, 140 LI-RADS5 were included (392 from 245 patients), which evaluated by follow-up imaging for LR-3 pathology results LR-4 LR-5 nodules. Data was collected retrospectively 3 T 1.5 scanners. All lesions categorized into 124 268 HCC lesions. Visual...

Aim: This study aimed to assess the effectiveness of using MRI-apparent diffusion coefficient (ADC) map-driven radiomics differentiate between hepatocellular adenoma (HCA) and carcinoma (HCC) features. Materials methods: The involved 55 patients with liver tumors (20 HCA 35 HCC), featuring 106 lesions equally distributed hepatic who underwent texture analysis on ADC map MR images. identified several imaging features that significantly differed HCC groups. Four classification models were...

Chronic hepatitis C virus infection is a major cause of mortality due to liver cirrhosis globally. Despite the advances in recent therapeutic strategies, there yet high burden HCV-related worldwide concerning low coverage newly developed antiviral therapies, insufficient validity current diagnostic methods for cirrhosis, and incomplete understanding pathogenesis this stage disease. Hence we aimed clarify molecular events identify liver-specific gene signature potentially improve diagnosis...

Background : Liver transplantation is a standard treatment for patients with end-stage liver disease (ESLD). However, increasing demand this and limited resources, it available only to who are more likely survive. The primary aim was determine prognostic factors survival. Methods We collected data from 597 adult ESLD, received single organ initial orthotopic (OLT) in our center between 20 March 2008 2018. In historical cohort study, univariate multiple Cox model were used of survival after...

Early hepatic artery thrombosis after liver transplant may be complicated by aggressive aspergillosis and bacterial infections that cause morbidity mortality. The definitive treatment of is revision transplant. However, sepsis a contraindication to A 37-year-old man developed at 3 days During the thrombosis, he multiple biliary, bacterial, fungal infections. Evaluation showed with intrahepatic abscesses. He was treated antibiotic antifungal drugs. Despite active sepsis, performed infection...

Pruritus is one of the disturbing complications induced by chronic liver disease (CLD), bearing a negative impact on patient quality life and potentially resulting in early transplants. Given main role autotaxin enzyme pruritus CLD suppressive effects melatonin expression gene, this study was designed to evaluate antipruritic effect patients with CLD. A double-blind, cross-over, randomized, placebo-controlled pilot trial conducted -induced pruritis. Patients were randomly assigned two groups...

Background: The main goal of the present study was to evaluate effect topical mastic oil, compared placebo on treatment functional dyspepsia (FD). Materials and Methods: Sixty-three patients with FD were included. Thirty-two subjects received oil (10 drops/TDS after meal) massage 31 sesame massage. Both groups pantoprazole (40 mg daily) along severity early satiation, postprandial fullness, epigastric pain burning assessed 4 weeks using Visual Analogue Scale (VAS) as well frequency symptoms....