- Fungal and yeast genetics research
- DNA Repair Mechanisms
- Genomics and Chromatin Dynamics
- Genetic Neurodegenerative Diseases
- Microtubule and mitosis dynamics
- melanin and skin pigmentation
- Insect Pest Control Strategies
- Cancer Cells and Metastasis
- Thermal and Kinetic Analysis
- Metal complexes synthesis and properties
- Cancer Genomics and Diagnostics
- Insect-Plant Interactions and Control
- Biochemical Analysis and Sensing Techniques
- Inorganic and Organometallic Chemistry
- Skin Protection and Aging
- Helicobacter pylori-related gastroenterology studies
- Cancer Immunotherapy and Biomarkers
- COVID-19 impact on air quality
- Lung Cancer Treatments and Mutations
- Gastric Cancer Management and Outcomes
- Research on Leishmaniasis Studies
- Bacterial Genetics and Biotechnology
University of Southern California
2019-2023
Southern California University for Professional Studies
2023
Veer Bahadur Singh Purvanchal University
2012-2022
University of Allahabad
2010
Background Visceral leishmaniasis (VL) is a deadly vector-borne disease. Approximately 90% of Indian VL cases occur in Bihar, where the sand fly, Phlebotomus argentipes, principal vector. Sand fly control Bihar consists indoor residual spraying (IRS), practice inner walls village dwellings with insecticides. Prior researchers have evaluated success IRS-control by estimating vector abundance houses, but number sampling periods (n = 2–3) were minimal, and outdoor-resting P. argentipes...
From yeast to humans, the cell cycle is tightly controlled by regulatory networks that regulate proliferation and can be monitored dynamic visual markers in living cells. We have observed S phase progression monitoring nuclear accumulation of FHA-containing DNA binding protein Tos4, which expressed G1/S transition. use Tos4 localization distinguish three classes replication mutants: those arrest with an apparent 1C content accumulate at restrictive temperature; 2C content, do not Tos4;...
A novel series of complexes the type [MLX_2] where M= Mn(II), Co(II), Ni(II), Cu(II) and Zn(II); X= C^- or NO_3^- were synthesized by template condensation hydrazine hydrate, acetaldehyde, 2,4-pentanedione, thiocarbohydrazide in presence divalent metal salt methanolic solution. The characterized with help elemental analysis, conductance measurements, magnetic electronic, NMR, XPS, infrared far spectral studies. Electronic spectra along moments suggest 6-coordinated octahedral geometry for...
Abstract Background Replication and transcription, the two key functions of DNA, require unwinding DNA double helix. It has been shown that replication origins in budding yeast, Saccharomyces cerevisiae contain an easily unwound stretch DNA. We have used a recently developed method for determining locations degrees stress-induced duplex destabilization (SIDD) all reported genome fission Schizosaccharomyces pombe . Results found are more susceptible to SIDD as compared non-origin intergenic...
Meiosis is a carefully choreographed dynamic process that re-purposes proteins from somatic/vegetative cell division, as well meiosis-specific factors, to carry out the differentiation and recombination pathway common sexually reproducing eukaryotes. Studies of individual variety different experimental protocols can make it difficult compare details between them. Using consistent protocol in otherwise wild-type fission yeast cells, this report provides an atlas protein behaviour...
Translesion synthesis polymerases (TLSPs) are non-essential error-prone enzymes that ensure cell survival by facilitating DNA replication in the presence of damage. In addition to their role bypassing lesions, TLSPs have been implicated meiotic double-strand break repair several systems. Here, we examine joint contribution four progression fission yeast Schizosaccharomyces pombe. We observed a dramatic loss spore viability lacking all TLSPs, which is accompanied disruptions chromosome...
Nobody had ever imagined that the virus found on Wuhan fish market would spread worldwide within a few months. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is seventh member of family infects humans. Going through corona-lane, mankind has faced different variants, i.e., COVID-19, delta B.1.617.2, and Omicron B.1.1.529. The outbreak COVID-19 created shocking situation for not only healthcare system, but also post-COVID-19 world, which witnessing huge damage in field...
ABSTRACT From yeast to humans, the cell cycle is tightly controlled by regulatory networks that regulate proliferation and can be monitored dynamic visual markers in living cells. We have observed S phase progression monitoring nuclear accumulation of FHA-containing DNA binding protein Tos4, which expressed G1/S transition. use Tos4 localization distinguish three classes replication mutants: those arrest with an apparent 1C content accumulate at restrictive temperature; 2C content, do not...
Abstract Meiosis is a carefully choreographed dynamic process that re-purposes proteins from somatic/vegetative cell division, as well meiosis-specific factors, to carry out the differentiation and recombination pathway common sexually reproducing eukaryotes. Studies of individual variety different experimental protocols can make it difficult compare details between them. Using consistent protocol in otherwise wild type fission yeast cells, this report provides an atlas protein behavior...
"Liquid biopsy" concentrates on the identification of ‘Circulating Tumor Cells (CTC) as well ‘Cell-free DNA’ (ctDNA) in systemic circulation individuals suffering from cancer, has received a lot interest due to its evident clinical implications for individualized therapy. CTC and ctDNA studies have created fresh diagnostic approaches are now foundations liquid biopsy. The existing study cancer diagnoses, prognosis prediction people having treatable diseases, observing therapy, patient...
The fourth most frequent cancer in the world is Gastric and also second leading cause of cancer-related fatalities. Despite substantial research into new diagnostic therapeutic agents, patients with advanced stomach have a low quality life dismal prognosis, treatment mostly cytotoxic chemotherapy. A deeper knowledge underlying molecular pathologies, as well their application toward development innovative strategies, essential for improving survival gastric