A5082060719- Genetic Associations and Epidemiology
- Gut microbiota and health
- Liver Disease Diagnosis and Treatment
- Diet and metabolism studies
- Cardiovascular Health and Risk Factors
- Nutrition, Genetics, and Disease
- Pancreatic function and diabetes
- Enterobacteriaceae and Cronobacter Research
- Cardiac Health and Mental Health
- Diet, Metabolism, and Disease
- Historical and modern epidemiology studies
- Digestive system and related health
Global Health Research Center of Central Asia
2024
The gut microbiota plays a fundamental role in the host's energy metabolism and development of metabolic diseases such as arterial hypertension, insulin resistance, atherosclerosis. Our study aimed to investigate potential hypertension among individuals Kazakh population without resistance. 16S rRNA gene sequencing faecal samples from 197 subjects was performed. Preliminary binary comparisons composition depending on presence resistance revealed statistically significant differences abundance
The increasing prevalence of type 2 diabetes (T2D) underlines the urgent need for proactive strategies to prevent and control T2D. A fairly large number studies show that T2D is a complex metabolic disease caused by lifestyle, environment genetic factors. Thus, study predisposition great importance. At same time, one most effective methods, besides genome-wide researches, use polymorphic markers various candidate genes, i.e., those protein products which (enzymes, regulatory proteins...