A5068271907- Alzheimer's disease research and treatments
- Nutrition, Genetics, and Disease
- Gut microbiota and health
- Neurological Disorders and Treatments
- Diet and metabolism studies
- Mitochondrial Function and Pathology
- Diet, Metabolism, and Disease
- Digestive system and related health
- Liver Disease Diagnosis and Treatment
- Chemical Reactions and Isotopes
- Food Industry and Aquatic Biology
- Biochemical effects in animals
- Healthcare Systems and Public Health
- Neurological Disease Mechanisms and Treatments
- Flavonoids in Medical Research
- Enterobacteriaceae and Cronobacter Research
- Ear and Head Tumors
- COVID-19 diagnosis using AI
- Photodynamic Therapy Research Studies
- Phonocardiography and Auscultation Techniques
- Coenzyme Q10 studies and effects
- Glutathione Transferases and Polymorphisms
- Medical and Biological Ozone Research
- Prion Diseases and Protein Misfolding
- Nuclear Receptors and Signaling
Global Health Research Center of Central Asia
2020-2023
National Center for Biotechnology
2021
Astana Medical University
2011-2018
Russian Academy of Sciences
2013
St. Petersburg Institute of Bioregulation and Gerontology
2012
Changes in the gut microbiota are increasingly recognised to be involved many diseases. This ecosystem is known shaped by factors, including climate, geography, host nutrition, lifestyle and medication. Thus, knowledge of varying populations with different habits important for a better understanding microbiome.We therefore conducted metagenomic analysis intestinal from Kazakh donors, recruiting 84 subjects, male female healthy subjects metabolic syndrome (MetS) patients aged 25-75 years,...
APP/PS1 double-transgenic mouse models of Alzheimer's disease (AD), which overexpress mutated forms the gene for human amyloid precursor protein (APP) and presenilin 1 (PS1), have provided robust neuropathological hallmarks AD-like pattern at early ages. This study characterizes immunocytochemical patterns AD brain as a model treated with EB101 vaccine. In this novel vaccine, new approach has been taken to circumvent past failures by judiciously selecting an adjuvant consisting physiological...
Introduction: APP/PS1 double-transgenic mouse models of Alzheimer’s disease (AD), which overexpress mutated forms the gene for human amyloid precursor protein (APP) and presenilin 1 (PS1), have provided robust neuropathological hallmarks an AD-like pattern at early ages. This study aimed to characterize immunocytochemical patterns AD brain, is treated with EB101 vaccine, as a model AD.Material methods: In this novel new approach has been taken circumvent past failures Aβ vaccines by...
Kleiber’s Law or E = M3/4 is a mathematical expression known since 1932 that outlines the relationship between mass (biomass) and use of energy. It compelling because it supports long standing observation larger animals appear to energy more efficiently than smaller ones. For example, an elephant’s weight 200,000 times mouse, but uses only about 10,000 fold energy; thus cat, having 100 spends roughly 33 In other words, bigger you are, less per gram tissue actually need stay alive. Many facts...
The quality and depth of content Web Science offers to researchers, authors, publishers, institutions sets it apart from other research databases.The inclusion Bulletin NAS RK in the Emerging Sources Citation Index demonstrates our dedication providing most relevant influential multidiscipline community. Қазақстан Республикасы Ұлттық ғылым
In the pathogenesis of cardiac autonomic neuropathy, disruptions in lipid metabolism occur, which subsequently influence reduction neural blood flow, leading to decreased conductivity heart. It is commonly believed that fat mass and obesity-associatedFTO gene a predisposing for obesity, its polymorphism rs12149832 plays crucial role obesity processes, particularly among Asian population. However, as today, there lack studies examining association this with neuropathy Kazakh The aim: To...
Introduction. It is known that cardiovascular diabetic neuropathy or cardiac autonomic plays a role in the pathogenesis of vascular damage and subsequent artery disease, which can lead to disability. Currently, genetic mechanisms development are interest. Objective study. To evaluate association polymorphisms rs1011970, rs62560775, rs72652411, rs564398 ANRIL gene (CDKN2B) with identify markers complications patients Kazakh population. Materials methods. A case-control study included 67...
This article presents a clinical observation of successful treatment patient with multiple cylindroma the scalp and trunk using photodynamic therapy (PDT) after radiotherapy. The first masses were found in 2008, at same time they surgically removed. There has been progression process since 2019 - on trunk. was another visit to doctors. After verification diagnosis radiation received. However, soon treatment, appearance new growth existing foci noted. A multistage PDT good cosmetic effect...
The quality and depth of content Web Science offers to researchers, authors, publishers, institutions sets it apart from other research databases.The inclusion Bulletin NAS RK in the Emerging Sources Citation Index demonstrates our dedication providing most relevant influential multidiscipline community. Қазақстан Республикасы Ұлттық ғылым
The density of taste buds, differences in genes encoding receptors, and other factors affect the on perception further food preferences. This study aimed to evaluate association between 24 single nucleotide polymorphisms preferences a Kazakh cohort. A total 400 subjects were recruited from an outpatient clinic genotyped for previously described as associated with eating behaviour ethnic groups. Regression analysis was conducted, adjusting age sex.
 Associations detected rs2290550...