Yerkebulan Talzhanov

ORCID: 0000-0003-1036-4943
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About
Contact & Profiles
Research Areas
  • Pancreatic and Hepatic Oncology Research
  • Pancreatitis Pathology and Treatment
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Pancreatic function and diabetes
  • Fibromyalgia and Chronic Fatigue Syndrome Research
  • Immunotherapy and Immune Responses
  • Nutrition, Genetics, and Disease
  • Fetal and Pediatric Neurological Disorders
  • Cardiac Imaging and Diagnostics
  • Cardiovascular Function and Risk Factors
  • Biochemical Analysis and Sensing Techniques
  • Intracranial Aneurysms: Treatment and Complications
  • Liver Disease Diagnosis and Treatment
  • Moyamoya disease diagnosis and treatment
  • Chemical Safety and Risk Management
  • Diet, Metabolism, and Disease
  • Immune Response and Inflammation
  • Occupational Health and Safety Research
  • Cancer Genomics and Diagnostics
  • Connective tissue disorders research
  • Genetic Associations and Epidemiology
  • Prenatal Screening and Diagnostics
  • Coronary Interventions and Diagnostics

National Center for Biotechnology
2016-2021

Global Health Research Center of Central Asia
2021

Institute of Chemical Biology and Fundamental Medicine
2021

Morgantown High School
2016

University of Pittsburgh
2013-2016

Irritant contact dermatitis is the most common work-related skin disease, especially affecting workers in "wet-work" occupations. This study was conducted to investigate association between single nucleotide polymorphisms (SNPs) within major histocompatibility complex (MHC) and irritant response a group of healthcare workers. 585 volunteer were genotyped for MHC SNPs patch tested with three different irritants: sodium lauryl sulfate (SLS), hydroxide (NaOH) benzalkonium chloride (BKC)....

10.3109/1547691x.2016.1173135 article EN Journal of Immunotoxicology 2016-06-03

After coronary stenting, the risk of developing restenosis is from 20 to 35 %. The aim present study investigate association genetic variation in candidate genes patients diagnosed with Kazakh population. Four hundred fifty-nine were recruited study; 91 also diabetes and excluded sampling. DNA was extracted salting-out method. genotyped for 53 single-nucleotide polymorphisms. Genotyping performed on QuantStudio 12K Flex (Life Technologies). Differences distribution BMI score among different...

10.1186/s40246-016-0077-z article EN cc-by Human Genomics 2016-06-08

The aim of this study was to investigate the association single nucleotide polymorphisms (SNPs) within genes involved in inflammation, skin barrier integrity, signaling/pattern recognition, and antioxidant defense with irritant susceptibility a group health care workers.The 536 volunteer subjects were genotyped for selected SNPs patch tested three model irritants: sodium lauryl sulfate (SLS), hydroxide (NaOH), benzalkonium chloride (BKC). Genotyping performed on genomic DNA using Illumina...

10.1097/jom.0000000000000784 article EN Journal of Occupational and Environmental Medicine 2016-05-19

Background: Ethnic differences exist in the frequencies of genetic variations that contribute to risk common disease. This study aimed analyse distribution several genes, previously associated with susceptibility type 2 diabetes and obesity-related phenotypes, a Kazakh population. Methods: A total 966 individuals belonging ethnicity were recruited from an outpatient clinic. We genotyped 41 single nucleotide polymorphisms (SNPs) other ethnic groups 31 these Hardy–Weinberg equilibrium. The...

10.2147/cia.s156044 article EN cc-by-nc Clinical Interventions in Aging 2018-03-01

The density of taste buds, differences in genes encoding receptors, and other factors affect the on perception further food preferences. This study aimed to evaluate association between 24 single nucleotide polymorphisms preferences a Kazakh cohort. A total 400 subjects were recruited from an outpatient clinic genotyped for previously described as associated with eating behaviour ethnic groups. Regression analysis was conducted, adjusting age sex.
 Associations detected rs2290550...

10.11134/btp.4.2021.2 article EN Eurasian journal of applied biotechnology 2021-12-23
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