A5030725927- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Cerebrovascular and Carotid Artery Diseases
- Moyamoya disease diagnosis and treatment
- Intracerebral and Subarachnoid Hemorrhage Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Global Health and Surgery
- History of Medical Practice
- Facial Nerve Paralysis Treatment and Research
- Global Healthcare and Medical Tourism
- Organ Donation and Transplantation
- COVID-19 and healthcare impacts
- Extracellular vesicles in disease
- Connective tissue disorders research
- Surgical Simulation and Training
- Parkinson's Disease and Spinal Disorders
- Craniofacial Disorders and Treatments
- Autophagy in Disease and Therapy
- Neurological Disease Mechanisms and Treatments
- Trigeminal Neuralgia and Treatments
- Augmented Reality Applications
- Cerebral Venous Sinus Thrombosis
- Spine and Intervertebral Disc Pathology
- Neurological Complications and Syndromes
- Anatomy and Medical Technology
National Research Center for Maternal and Child Health
2017-2024
National Center of Neurology and Psychiatry
2018
Background Microvascular decompression (MVD) remains the primary surgical treatment for trigeminal neuralgia due to its positive postoperative results. This study aims evaluate outcomes of patients with who underwent MVD. Additionally, paper offers a detailed explanation methodology MVD employed at neurosurgical hospital in Kazakhstan. Methods The involved 165 medical records between 2018 and 2020. Out these patients, 90 (54.55%) were included final analysis further evaluated using Barrow...
Percutaneous spinal endoscopy is used for the treatment of disorders lumbar spine, as it has several advantages over traditional surgical methods. The performance percutaneous not possible without applying anesthesia Two types (local and general) are endoscopy. Both, local general approaches contribute to safety in procedures. Although believed that method more benefits anesthesia, such lowering risk postoperative neurological complications a patient, literature on topic inconclusive. study...
Background: Arteriovenous malformations (AVMs) are abnormal tangles of arteries and veins that connect directly without an intervening capillary bed. Epileptic seizures the second most common symptom in patients with brain AVMs, occurring 30 to 50% cases. However, exact mechanism epileptic seizure development AVMs remains unclear. In this study, we aimed investigate factors associated arteriovenous malformation Kazakhstan. Methods: A case–control study was conducted, which included 163...
Pericytes possess high multipotent features and cell plasticity, produce angiogenic neurotrophic factors that indicate their regenerative potential. The aim of this study was to investigate whether transplantation adipose-derived pericytes can improve functional recovery neurovascular plasticity after ischemic stroke in rats. Rat were isolated from subcutaneous adipose tissue by fluorescence-activated sorting. Adult male Wistar rats subjected 90 min middle cerebral artery occlusion followed...
Rupture of intracranial aneurysms (RIA) leads to subarachnoid hemorrhage (SAH) with severe consequences. Although risks for RIA are established, the results vary between ethnic groups and were never studied in Kazakhstan. This study aimed establish risk factors Kazakh population. METHODS: Retrospective analysis 762 patients single IAs, who attended neurosurgical center from 2008 until 2018, was conducted. Demographic characteristics, such as age, sex, smoking status, hypertension considered....
(1) Background: This report describes the surgical management of a case concurrent AVM with involvement dural arteries and moyamoya syndrome. Given infrequency this combination, there is currently no established strategy available. (2) Case Description: A 49-year-old male patient multiple symptoms including headaches, tinnitus, visual impairment diagnosed coexistence an arteriovenous malformation syndrome was admitted to national tertiary hospital. The underwent through embolization from...
Background: A vein of Galen aneurysmal malformation (VGAM) is a rare congenital cerebral vascular condition with high mortality rate if left untreated. This study describes the long-term outcomes patients VGAM, who were treated endovascular embolization. Methods: retrospective analysis focused on VGAM underwent one or more embolization sessions between January 2008 and December 2022. The included newborns children under 18 years. Data encompassed clinical demographic characteristics, types...
Arteriovenous malformations of the brain (bAVMs) are plexuses pathological arteries and veins that lack a normal capillary system between them. Intracranial hemorrhage (hemorrhagic stroke) is most frequent clinical manifestation AVM, leading to lethal outcomes especially high among children young people. Recently, high-throughput genome sequencing methods have made notable contribution research progress in this subject. In particular, whole-exome (WES) allow identification novel mutations....
The use of flow diverter (FD) stents is continually expanding. Aneurysms on arterial bifurcation typically have an undesirable anatomical form, are frequently wide-necked, and include one or more side-branch arteries. In recent years, the off-label diversion in treating intracranial aneurysms beyond internal carotid artery has become increasingly popular. This study reports our center's initial experience with FD devices, documenting occlusion outcomes using O'Kelly-Marotta modified...
Brain AVMs are the abnormal connection between veins and arteries of brain, that can lead to headaches, seizures, hemorrhages. The choice treatment for bAVMs depends on several factors, such as size location malformations, severity symptoms, risk hemorrhage. ARUBA was a clinical trial aimed determine best approach unruptured AVMs. Its results showed conservative management associated with significantly lower death or stroke compared intervention, leading shift in practice neurosurgeons. In...
BACKGROUND AND IMPORTANCE: The case describes the management of a giant and recurrent aneurysm in patient. treatment involved combination microsurgical protective low-flow, followed by high-flow revascularization parent artery occlusion. CLINICAL PRESENTATION: patient presented with severe headaches progressive visual impairment. Brain magnetic resonance imaging revealed saccular intracranial left internal carotid artery. examination also hypoplasia right anterior cerebral fetal-type...
Background: Deep brain stimulation (DBS) is an effective treatment for movement disorders, but its long-term efficacy may be undermined by hardware complications such as lead fractures. These increase healthcare costs and necessitate surgical revisions. The frequency, timing, clinical factors associated with fractures remain poorly understood. Objective: This study aimed to determine the incidence, in a large cohort of DBS patients over 10-year period. Methods: retrospective analyzed data...
Conus medullaris arteriovenous fistulas (AVFs) are rare among spinal vascular malformations. This case report highlights the presentation, diagnostic work-up, and management of a patient with perimedullary conus AVF type IVa. A 29-year-old male presented progressive weakness numbness in left leg. Thoracic magnetic resonance imaging (MRI) showed increased arterial supply dural membrane large, smoldering, twisting spaces from T8 to L1 central point which many abnormal vessels radiated....
Neurosurgery education in Kazakhstan has 55 years of history. The first neurosurgery department was established 1964 the city Almaty, South (the former capital Kazakhstan). headed by pioneer Kazakhstani neurosurgeons, Prof. Yevgeniya Azarova. A new system adopted after a while. To date, 4 medical universities and 1 neurosurgical center have that prepares around 10 neurosurgeons annually. country’s populations are currently served more than 300 neurosurgeons. However, isolated regions lack...
Extracranial carotid artery aneurysms (ECAA) and carotid-cavernous fistulas (CCF) are rare arterial pathologies with severe complications increased risk of mortality. The optimal treatment approach for this combined condition is a topic debate among neurosurgeons neuroradiologists, standardized protocol has yet to be established. aim case report was demonstrate the management combination ECAA CCF in patients. strategy included two-step procedure endovascular embolization followed by dual...
Flow diverter stents have become the standard approach to managing intracranial aneurysms; however, in some cases of complex, wide-necked aneurysms, poor outcomes due stent occlusion been reported. We report case a giant internal carotid artery aneurysm treated by high-flow extracranial-intracranial (EC-IC) bypass with flow deployment. Seven months post-operatively, radiographic imaging demonstrated and parent artery, further ischemic events prevented collateral from high bypass. This...