A5070758840- Gut microbiota and health
- Probiotics and Fermented Foods
- Long-Term Effects of COVID-19
- Vitamin D Research Studies
- Genomics and Phylogenetic Studies
- Digestive system and related health
- Healthcare Systems and Public Health
- Diet and metabolism studies
- Tryptophan and brain disorders
- COVID-19 Clinical Research Studies
- Phytochemical and Pharmacological Studies
- Clostridium difficile and Clostridium perfringens research
- SARS-CoV-2 and COVID-19 Research
- Hibiscus Plant Research Studies
- Food Security and Health in Diverse Populations
- Nutrition, Genetics, and Disease
- Carcinogens and Genotoxicity Assessment
- Microbial Metabolites in Food Biotechnology
Astana Medical University
2023-2025
National Center for Biotechnology
2021
Nazarbayev University
2015-2018
Low vitamin D status is linked to disturbance in cognitive performance. This study explored possible ways how composition and functional capacity of the gut microbiome affects metabolism, directing serum (VitD) levels memory impairmets. It was found that composition, characterized by an increase relative abundance Enterococcus correlated with deficiency and, as consequence, impairments. A key mechanism identified differential utilization short-chain fatty acids (SCFAs) produced bacteria...
Changes in the gut microbiota are increasingly recognised to be involved many diseases. This ecosystem is known shaped by factors, including climate, geography, host nutrition, lifestyle and medication. Thus, knowledge of varying populations with different habits important for a better understanding microbiome.We therefore conducted metagenomic analysis intestinal from Kazakh donors, recruiting 84 subjects, male female healthy subjects metabolic syndrome (MetS) patients aged 25-75 years,...
The aims of this study were to analyze cytokine profiles in patients with COVID-19, gain insights into the immune response during acute infection, identify cytokines associated disease severity and post-COVID complications, explore potential biomarkers for prognosis therapeutic targets. Using a multiplex analysis, we studied pattern 294 COVID-19 varying severities infection. Our findings revealed that was elevated levels IL-15, IL-8, fractalkine. Severe/extremely severe forms comparison...
Introduction Probiotics and prebiotics are widely used for recovery of the human gut microbiome after antibiotic treatment. High usage is especially common in children with developing microbiome. We hypothesized that dry Mare’s milk, which rich biologically active substances without containing live bacteria, could be as a prebiotic promoting microbial diversity following treatment children. The present pilot study aims to determine impacts milk on bacterial communities when administered...
The aim of this study is determine the in vitro and vivo antiradical properties cytoprotective activity Allium nutans L. honey extract. extracts were investigated rabbit alveolar macrophages human foreskin fibroblast (hFFs) cells presence doxorubicin, a cytotoxic substance using DPPH ABTS assays. activities determined 18 Wistar rats divided into three different groups, negative control, two other groups with experimentally induced hepatotoxicity by single intraperitoneal injection 50% carbon...
Введение. Использование лекарственных трав приобретает все большее значение как альтернативного лечения во многих странах для paн и oжoгoвых тpaвм. Pacтения из cемейcтвa Гpечишных coдеpжaт биoлoгичеcкие aктивные вещеcтвa paзличных клaccoв пpиpoдных coединений: флaвонoиды, дубильные вещеcтвa, теpпенoиды, aминoкиcлoты, углевoды, микpoэлементы, эфиpные мacлa, что определяет их применение в народной медицине, кaк пpoтивoвocпaлительного средства создает перспективы дальнейшего экспериментального...
We announce the draft genome sequence of type strain Lactobacillus rhamnosus CLS17 (2,889,314 nt, with a GC content 46.8%), which is one most prevalent lactic acid bacteria present during manufacturing process dairy products; consists 71 large contigs (>100 bp in size). It contains 2,643 protein-coding sequences, single predicted copies 5S, 16S, and 23S rRNA genes, 51 tRNAs.
Abstract. Nurgaziyev M, Atenov Y, Khassenbekova Z, Akpanova S, Rysbekov K, Kozhakhmetov Nurgozhina A, Sergazy Chulenbayeva L, Ospanova Tuyakova Mukhambetganov N, Sattybayeva R, Urazova Galymgozhina Zhumadilova Gulyaev Kushugulova A. 2020. Effect of mare’s milk prebiotic supplementation on the gut microbiome and immune system following antibiotic therapy. Biodiversitas 21: 5065-5071. Antibiotic treatment can severely affect for short-term long-term consequences. Probiotic supplements are...