A5089043372- Mosquito-borne diseases and control
- Insect behavior and control techniques
- Forensic Entomology and Diptera Studies
- Viral Infections and Vectors
- Gut microbiota and health
- Insect Pest Control Strategies
- Insect and Pesticide Research
- Malaria Research and Control
- Physiological and biochemical adaptations
- Insect symbiosis and bacterial influences
- Tryptophan and brain disorders
- Neurobiology and Insect Physiology Research
- Computational Drug Discovery Methods
- Clostridium difficile and Clostridium perfringens research
- Yersinia bacterium, plague, ectoparasites research
- Insect Resistance and Genetics
- Analytical Chemistry and Chromatography
- Diptera species taxonomy and behavior
- Insect Utilization and Effects
- Insect and Arachnid Ecology and Behavior
- Climate Change and Health Impacts
- Insect-Plant Interactions and Control
- Environmental and Biological Research in Conflict Zones
- Food Security and Health in Diverse Populations
- Protein Structure and Dynamics
Nazarbayev University
2023-2025
Sirius University of Science and Technology
2025
Peter the Great St. Petersburg Polytechnic University
2020
Zoological Institute
1972-2016
Russian Academy of Sciences
1995-2013
Institut de Biologie Moléculaire des Plantes
2008
Vavilov Institute of General Genetics
2003
Recent studies have suggested that periodontal disease and alterations in the oral microbiome may be associated with cognitive decline Alzheimer’s (AD) development. Here, we report a case-control study of microbiota diversity AD patients compared to healthy seniors from Central Asia. We characterized bacterial taxonomic composition (n = 64) group 71) using 16S ribosomal RNA sequencing. According our results, has higher microbial diversity, an increase Firmicutes decrease Bacteroidetes group....
Recent studies highlight the crucial role of gut microbiome in post-infectious complications, especially patients recovering from severe COVID-19. Our research aimed to explore connection between changes and cytokine profile with post-COVID syndrome. Using 16S rRNA amplicon sequencing, we analyzed composition 60 COVID-19 over course one year. We also measured levels serum cytokines chemokines using Milliplex system. results showed that SARS-CoV-2 infection cases, those complicated by...
The longevity is influenced by genetic, environmental, and lifestyle factors. specific changes that occur in the gut microbiome during aging process, their relationship to immune function, have not yet been fully understood. ongoing research of other based on cohort Kazakhstan provides preliminary information longevity-related aging, where cytokine expression associated with microbial communities functions.
Recent studies strongly suggest that gut microbiome can influence brain functions and contribute to the development of Alzheimer’s disease (AD). However, reported changes in microbiomes AD patients from different countries are not similar, more research is needed reveal relationships between human diverse ethnic populations. There also an assumption microbiome‐associated peripheral inflammation might drive sporadic AD. This cross‐sectional study aimed at analyzing microbial profile exploring...
Low vitamin D status is linked to disturbance in cognitive performance. This study explored possible ways how composition and functional capacity of the gut microbiome affects metabolism, directing serum (VitD) levels memory impairmets. It was found that composition, characterized by an increase relative abundance Enterococcus correlated with deficiency and, as consequence, impairments. A key mechanism identified differential utilization short-chain fatty acids (SCFAs) produced bacteria...
Background: The impact of maternal obesity on offspring health remains a major and pressing issue. We investigated its the development infant gut microbiome during first six months life, examining taxonomic composition, metabolic pathways, antibiotic resistance genes. Methods: Twenty-four mother–infant pairs were divided into maternally obese (OB, BMI > 36) normal weight (BM) groups. Shotgun metagenomic sequencing was performed stool samples collected at birth 1, 3, 6 months. A total 12...
<title>Abstract</title> The gut microbiome undergoes substantial modifications during pregnancy, yet its postpartum adaptations remain poorly understood, particularly with respect to the influence of parity. Here, we investigated impact childbirth history on maternal composition and function one month postpartum. By conducting metagenomic sequencing analysis 60 participants (34 mothers 26 controls), demonstrated significant differences in microbial diversity community structure between...
Abstract The inconsolable crying of a child for no apparent reason at an early age is source excitement and anxiety parents. Previous studies have reported that may be caused by discomfort associated with the occupation intestines newborn microbiota its vital activity. We conducted prospective observational study in which 62 newborns their mothers were recruited. comprised two groups, each consisting 15 infants colic 21 controls. Colic control groups vaginally born exclusively breastfed....
Abstract In Chlamydomonas reinhardtii, 259 tRNA genes were identified and classified into 49 isoaccepting families. By constructing phylogenetic trees, we determined the evolutionary history for each gene family. The majority of sequences are more closely related to their plant counterparts than animals ones. Northern experiments also permitted us show that at least one member isoacceptor family is transcribed correctly processed in vivo. A short stretch T residues known be a signal...
The aims of this study were to analyze cytokine profiles in patients with COVID-19, gain insights into the immune response during acute infection, identify cytokines associated disease severity and post-COVID complications, explore potential biomarkers for prognosis therapeutic targets. Using a multiplex analysis, we studied pattern 294 COVID-19 varying severities infection. Our findings revealed that was elevated levels IL-15, IL-8, fractalkine. Severe/extremely severe forms comparison...
Objective The primary objective is to study the impact of gut microbiota and their interactions with diverse immunological markers on development rheumatoid arthritis. Methods This was performed in Astana, Kazakhstan, included 77 Kazakh female patients older than 18 years, who met American College Rheumatology 2010 classification criteria for arthritis (RA), 113 healthy controls. DNA extracted from fecal samples obtained all participants subsequent sequencing at 16S rRNA gene V1-V3 locus,...
ABSTRACT This study provides a comprehensive assessment of how urban-rural divides influence gut microbial diversity and composition across the distinct geographical landscapes Kazakhstan, elucidating intricate interplay between lifestyle, environment, microbiome. In this prospective cohort study, we enrolled 651 participants from urban centers rural settlements following ethical approval informed consent. Comprehensive demographic, dietary, stool sample data were collected. 16S rRNA gene...