A5076212480- Cancer-related gene regulation
- Epigenetics and DNA Methylation
- Cancer Genomics and Diagnostics
- Genomics and Chromatin Dynamics
- Protein Degradation and Inhibitors
- Ubiquitin and proteasome pathways
- Transition Metal Oxide Nanomaterials
- ZnO doping and properties
- Gas Sensing Nanomaterials and Sensors
Xiamen University
2012-2023
Abstract Menin is necessary for the formation of menin/mixed lineage leukemia (MLL) complex and recruited directly to chromatin. an important tumor suppressor in several cancer types, including lung cancer. Here, we investigated role MLL menin-regulated tumorigenesis. Ablation suppressed KrasG12D-induced tumorigenesis a genetically engineered mouse model. deficiency decreased histone H3 lysine 4 trimethylation (H3K4me3) subsequently expression Ras protein-specific guanine...
<div>Abstract<p>Menin is necessary for the formation of menin/mixed lineage leukemia (MLL) complex and recruited directly to chromatin. Menin an important tumor suppressor in several cancer types, including lung cancer. Here, we investigated role MLL menin-regulated tumorigenesis. Ablation suppressed Kras<sup>G12D</sup>-induced tumorigenesis a genetically engineered mouse model. deficiency decreased histone H3 lysine 4 trimethylation (H3K4me3) subsequently expression...
Supplementary Figure from Loss of MLL Induces Epigenetic Dysregulation Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis
Supplementary Figure from Loss of MLL Induces Epigenetic Dysregulation Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis
Supplementary Figure from Loss of MLL Induces Epigenetic Dysregulation Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis
Supplementary Figure from Loss of MLL Induces Epigenetic Dysregulation Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis
Supplementary Figure from Loss of MLL Induces Epigenetic Dysregulation Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis
Supplementary Data from Loss of MLL Induces Epigenetic Dysregulation Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis
Supplementary Data from Loss of MLL Induces Epigenetic Dysregulation Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis
<div>Abstract<p>Menin is necessary for the formation of menin/mixed lineage leukemia (MLL) complex and recruited directly to chromatin. Menin an important tumor suppressor in several cancer types, including lung cancer. Here, we investigated role MLL menin-regulated tumorigenesis. Ablation suppressed Kras<sup>G12D</sup>-induced tumorigenesis a genetically engineered mouse model. deficiency decreased histone H3 lysine 4 trimethylation (H3K4me3) subsequently expression...
Supplementary Figure from Loss of MLL Induces Epigenetic Dysregulation Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis
Supplementary Figure from Loss of MLL Induces Epigenetic Dysregulation Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis
Supplementary Figure from Loss of MLL Induces Epigenetic Dysregulation Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis
Supplementary Figure from Loss of MLL Induces Epigenetic Dysregulation Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis
Supplementary Figure from Loss of MLL Induces Epigenetic Dysregulation Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis
Supplementary Figure from Loss of MLL Induces Epigenetic Dysregulation Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis
Supplementary Figure from Loss of MLL Induces Epigenetic Dysregulation Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis
Supplementary Data from Loss of MLL Induces Epigenetic Dysregulation Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis
Supplementary Figure from Loss of MLL Induces Epigenetic Dysregulation Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis
Supplementary Figure from Loss of MLL Induces Epigenetic Dysregulation Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis
Supplementary Data from Loss of MLL Induces Epigenetic Dysregulation Rasgrf1 to Attenuate Kras-Driven Lung Tumorigenesis