A5034115198- Acute Ischemic Stroke Management
- Stroke Rehabilitation and Recovery
- Traumatic Brain Injury and Neurovascular Disturbances
- Cerebrovascular and Carotid Artery Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Long-Term Effects of COVID-19
- Thermal Regulation in Medicine
- COVID-19 and healthcare impacts
- COVID-19 Clinical Research Studies
- Neurological Disease Mechanisms and Treatments
- Acute Kidney Injury Research
- Venous Thromboembolism Diagnosis and Management
- Cardiac Imaging and Diagnostics
- Cardiac, Anesthesia and Surgical Outcomes
- Respiratory Support and Mechanisms
- Atrial Fibrillation Management and Outcomes
- Neurological Disorders and Treatments
- Intensive Care Unit Cognitive Disorders
- Peripheral Artery Disease Management
University Hospital Carl Gustav Carus
2019-2024
TU Dresden
2019-2023
Klinik und Poliklinik für Neurologie
2023
Klinik und Poliklinik für Psychotherapie und Psychosomatik
2020
Introduction Recent exploratory analysis suggested comparable outcomes among stroke patients undergoing endovascular therapy (EVT) for anterior circulation large vessel occlusion, whether selected via the telestroke network or admitted directly to an EVT-capable centre. We further studied role of telemedicine in selection ischaemic potentially eligible EVT. Methods prospectively included consecutive with occlusion who underwent EVT at our neurovascular centre (January 2016 March 2018)....
Introduction: Arterial hypertension is the most frequent cause for spontaneous intracerebral hemorrhage (sICH) and may also left ventricular hypertrophy (LVH). We sought to analyze whether hypertensive sICH etiology associated with LVH. Methods: analyzed consecutive patients who were admitted our tertiary stroke center during a four-year period underwent transthoracic echocardiography (TTE) as part of diagnostic work-up. defined typical localization in arterial no other identified etiology....
Background: The optimal sedative regimen with general anesthesia (GA) or conscious sedation for patients undergoing endovascular therapy (EVT) remains controversial. Apart from regimen, the duration of anesthetic exposure may affect clinical outcomes. We aimed to determine whether there is an association between time and outcomes in mechanically ventilated stroke EVT large vessel occlusion. Methods: This was observational study consecutive ischemic who underwent anterior circulation...
Malignant middle cerebral artery infarction is a potentially life-threatening disease. Decompressive hemicraniectomy constitutes an evidence-based treatment practice, especially in patients under 60 years of age; however, recommendations with respect to postoperative management and particularly duration sedation lack standardization.This survey study aimed analyze the current situation malignant following neurointensive care setting.From 20 September 2021 31 October 2021, 43 members...
Introduction: While observational data suggest that dexmedetomidine may have neuroprotective effects on ischemic brain, its clinical use in acute stroke is limited due to concerns about cerebral vasoconstriction. We aimed examine the impact of outcomes patients with anterior circulation large vessel occlusion (acLVO) requiring neurocritical care after endovascular therapy (EVT). Methods: extracted from our registry for consecutive acLVO who underwent EVT and subsequent (12/2019-12/2022)....
Hypothermia may be neuroprotective in acute ischemic stroke. Patients with anterior circulation large vessel occlusion (acLVO) are frequently hypothermic after endovascular therapy (EVT). We sought to determine whether this inadvertent hypothermia is associated improved outcome.We extracted data of consecutive patients (January 2016 May 2019) who received EVT for acLVO from our prospective register all screened at tertiary stroke center. assessed functional outcome 3 months and performed...
Introduction: Density of hyperdense middle cerebral artery sign (HMCAS) quantified via Hounsfield units (HU) on CT may predict clot composition and stroke TOAST subtype, with clots from cardioembolism displaying lower HMCAS densities due to fibrin predominance than erythrocyte-dominant originating large atherosclerosis (LAA). Hypothesis: We hypothesized that embolic undetermined source (ESUS) is linked higher density its high probability a cardiac as surrogate marker predicts successful...
Introduction: A recent exploratory analysis suggested comparable outcomes among ischemic stroke patients undergoing endovascular therapy (EVT) for anterior circulation large vessel occlusion (acLVO), regardless whether selected via telestroke or admitted directly to an EVT-capable center. The aim of this study was determine the benefit EVT in prospectively registered acLVO. Methods: We studied consecutive with acLVO who underwent at our tertiary center between January 2016 and March 2018....
Introduction: While data from randomized controlled trials suggest an overall benefit of endovascular therapy (EVT) in older patients suffering anterior circulation large vessel occlusion (acLVO), real world evidence is lacking. We aimed to explore the likelihood achieving favorable stroke outcomes octogenarians undergoing EVT for acLVO. Methods: prospectively studied consecutive ischemic aged 80 years or who were considered due acLVO at our tertiary center (01/2016-06/2018). compared...
Introduction: Hypothermia may be neuroprotective in acute ischemic stroke. Stroke patients with anterior circulation large vessel occlusion (acLVO) who receive endovascular therapy (EVT) are frequently hypothermic after the procedure. We sought to analyze whether this unintended hypothermia was associated improved functional outcome. Methods: extracted data of consecutive (01/2016-04/2019) from our prospective EVT database that includes all screened for at center. included acLVO received and...
Introduction: To explore kidney safety profile of osmotic diuretic mannitol in patients with malignant middle cerebral artery (MCA) infarction. Methods: We analyzed data from consecutive MCA infarction (01/2008-12/2017). Malignant was defined according to clinical and radiographic DESTINY criteria. Clinical laboratory variables were collected for all patients. compared endpoints including acute failure (AKF; Kidney Disease: Improving Global Outcomes [KDIGO] definition) hemodialysis between...