- Gastrointestinal motility and disorders
- Ophthalmology and Visual Impairment Studies
- Drug Solubulity and Delivery Systems
- Advanced Drug Delivery Systems
- Monoclonal and Polyclonal Antibodies Research
- Ophthalmology and Visual Health Research
- Retinal Imaging and Analysis
- Wood Treatment and Properties
- Retinopathy of Prematurity Studies
- Retinal Diseases and Treatments
- Diet and metabolism studies
- Digestive system and related health
- Helicobacter pylori-related gastroenterology studies
- Immunotherapy and Immune Responses
- Corneal surgery and disorders
- Clostridium difficile and Clostridium perfringens research
- Drug Transport and Resistance Mechanisms
- Tree Root and Stability Studies
- Gut microbiota and health
- Cancer Immunotherapy and Biomarkers
- Pharmaceutical studies and practices
- Structural Load-Bearing Analysis
- Structural Behavior of Reinforced Concrete
- Clinical Nutrition and Gastroenterology
- Inclusion and Disability in Education and Sport
University of Ulster
2019-2025
Queen's University Belfast
2014-2025
Royal Victoria Hospital
2025
Belfast Health and Social Care Trust
2020-2025
Newcastle University
2023
F-star (United Kingdom)
2019-2021
ENVIRON (United States)
2014
Cambridge Life Sciences (United Kingdom)
2013
MSD (UK) Limited (United Kingdom)
2011-2012
University of London
2007-2010
To use rodent models effectively in in-vivo investigations on oral drug and vaccine delivery, the conditions gastrointestinal tract must be understood. Some fundamental information is currently unavailable or incomplete. We have investigated pH, water content lymphoid tissue distribution along tract, as well stomach volume, these were critical to our pH-responsive delivery colonic vaccination. The observed values compared with those man an indication of validity model. mouse pH was 3.0 (fed)...
Background/Objectives: The measurement of axial length (AL) is important to monitor the success interventions slow childhood myopia, but traditional biometers are expensive for clinicians acquire. To address this, Oculus has developed Myopia Master (MM), which measures auto-refraction (AR), corneal curvature (CC) and AL. This study compared inter-instrument inter-examiner on MM, IOL 700 (Carl Zeiss Meditec, Jena, Germany) NVisionK-5001 (Shin-Nippon, Tokyo, Japan) in myopic children. Methods:...
Background A pilot eyecare programme aimed to address the urgent eye health needs of older Zanzibari craftswomen. We investigated impact correcting presbyopia on their subjective well-being (SWB) 6 months post-correction and assessed cost-effectiveness a women-targeted correction programme. Methods This study involved craftswomen aged 40 with presenting corrected distance visual acuity better than 6/12 in both eyes were presbyopic. Using before–after method, we SWB 10-point scale before...
Objectives To determine whether implementation of comprehensive in-school eyecare results in measurable benefits for children and young people terms visual status, classroom behaviours how well their needs are met. Design School-based observational study. Participants & Methods 200 pupils [mean age 10 years 9 months, 70% male, majority moderate (40%) or severe (35%) learning difficulty] a special education school the UK. A sector-agreed framework including full eye examination cycloplegic...
Polysaccharide-based colonic drug delivery requires that the polysaccharide in question avoids pancreatic digestion but undergoes fermentation by bacteria. Resistance of such dosage forms to enzyme is generally only tested fasted state, despite higher enzymatic challenge fed state. Theophylline pellets coated with a polysaccharide-based (amylose) colon-specific film were administered seven healthy volunteers (two-way crossover study, fed/fasted). The transit through gut was followed gamma...
Objective To understand if presbyopia correction could empower older craftswomen entrepreneurs living in Zanzibar. Design Mixed-method, before-after intervention study. Setting Unguja and Pemba islands, Participants 209 (weaving, tailoring sewing, pottery producing oil making soaps) 40 years with correctable presbyopia, no other ocular morbidities. Intervention Eye health assessment near vision spectacle for 6 months. Primary secondary outcomes Change economic, social, psychological...
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Accessible summary Children with learning disabilities often have problems their eyesight. We tested the eyes of nine children and checked whether they needed glasses or bigger print. found that when got what to see better, behaviour improved. This is important because need be able as well anyone else. Abstract Background identified special educational needs are at higher risk than other having visual not adequately met. paper evaluates impact addressing these on academic achievements in a...
Improvements in the structural performance of glulam timber beams by inclusion reinforcing materials can increase both service and ultimate capacity. This paper describes a series four-point bending tests conducted, under loads to failure, on unreinforced, reinforced post-tensioned beams, where tendon used is 12 mm dia. basalt fibre-reinforced polymer. The research designed evaluate benefits offered including an active reinforcement contrast passive typically within strengthening works,...