A5045874010- Multiple Sclerosis Research Studies
- Parkinson's Disease Mechanisms and Treatments
- Adipokines, Inflammation, and Metabolic Diseases
- Polyomavirus and related diseases
- Pneumocystis jirovecii pneumonia detection and treatment
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Blood properties and coagulation
- T-cell and B-cell Immunology
- Allergic Rhinitis and Sensitization
- Muscle Physiology and Disorders
- Erythrocyte Function and Pathophysiology
- Peripheral Neuropathies and Disorders
- Dermatology and Skin Diseases
- Genetic Neurodegenerative Diseases
University of Southampton
2023-2024
University Hospital Southampton NHS Foundation Trust
2024
National and Kapodistrian University of Athens
2022
Eginition Hospital
2022
North Bristol NHS Trust
2021
University of Bristol
2021
Lower urinary tract symptoms (LUTS) are common in persons with progressive multiple sclerosis (pwPMS), who may consequently limit their fluid intake. We aimed to investigate the hypothesis that LUTS associate objective evidence of inadequate hydration status pwPMS.
Myotonic Dystrophies (DM, Dystrophia Myotonia) are autosomal dominant inherited myopathies with a high prevalence across different ethnic regions. Despite some differences, mainly due to the pattern of muscle involvement and age onset, both forms, DM1 DM2, share many clinical genetic similarities. In this study, we retrospectively analyzed medical record files 561 Greek patients, 434 127 DM2 diagnosed in two large academic centers between 1994-2020. The mean at onset symptoms was 26.2 ± 15.3...
Recent evidence suggests that systemic conditions, particularly those associated with inflammation, can affect erythrocyte deformability in the absence of haematological conditions. In this exploratory study, we investigated relationship between inflammatory status and (using osmotic gradient ektacytometry) a heterogenous study population consisting individuals no medical concerns, chronic acute illness, providing wide range inflammation severity. 22 participants were included prospective...
Background: The cytotoxic T-lymphocyte antigen-4 (CTLA-4) pathway acts as a negative immune regulator of T-cell activation and promotes self-tolerance. Case: We report the first case biopsy-proven central nervous system inflammatory demyelination in context primary immunodeficiency novel CTLA-4 variant. Conclusion: This has significant implications for development treatments autoimmune conditions including multiple sclerosis further emphasises need caution with clinical use checkpoint...