A5100324711- Pain Mechanisms and Treatments
- Intensive Care Unit Cognitive Disorders
- Gut microbiota and health
- Corporate Finance and Governance
- Energy, Environment, Economic Growth
- Genomics, phytochemicals, and oxidative stress
- Anesthesia and Neurotoxicity Research
- Tryptophan and brain disorders
- Nerve injury and regeneration
- Law, Economics, and Judicial Systems
- Neurological Disorders and Treatments
- Regional Economics and Spatial Analysis
- Quantum Mechanics and Non-Hermitian Physics
- Neuroinflammation and Neurodegeneration Mechanisms
- Economic Growth and Productivity
- Financial Markets and Investment Strategies
- Global trade and economics
- Firm Innovation and Growth
- Neurological Disease Mechanisms and Treatments
- Topological Materials and Phenomena
- Eicosanoids and Hypertension Pharmacology
- Economic and Technological Innovation
- Biochemical Acid Research Studies
- Game Theory and Voting Systems
- Cleft Lip and Palate Research
Huazhong University of Science and Technology
2011-2025
Tongji Hospital
2018-2025
National Clinical Research Center for Digestive Diseases
2025
East China Jiaotong University
2023
Jiangxi Mental Health Center
2023
Wuhan National Laboratory for Optoelectronics
2021
Xiamen University
2019-2020
Sun Yat-sen University
2019
City University of New York
2018
George Washington University
2013
Abstract Patients with chronic neuropathic pain frequently suffer from symptoms of anhedonia, which is a core symptom depression. Accumulating studies suggest that gut microbiota may play role in depression via gut–microbiota–brain axis. However, it unknown whether plays pain-associated anhedonia. Here, we used rat model spared nerve injury (SNI). Hierarchical cluster analysis sucrose preference test (SPT) results was to classify the SNI rats or without anhedonia-like phenotype. The 16S...
Postoperative cognitive dysfunction (POCD) is a severe neurological complication after anesthesia and surgery. However, there still lack of effective clinical pharmacotherapy due to its unclear pathogenesis. Caffeic acid phenethyl ester (CAPE), which obtained from honeybee propolis medicinal plants, shows powerful antioxidant, anti-inflammatory, immunomodulating properties. In this study, we aimed evaluate whether CAPE mitigated impairment following surgery potential underlying mechanisms in...
Anesthesia and surgery can cause delirium-like symptoms postoperatively. Increasing evidence suggests that gut microbiota is a physiological regulator of the brain. Herein, we investigated whether plays role in postoperative delirium (POD).Mice were separated into non-POD POD phenotypes after abdominal by applying hierarchical clustering analysis to behavioral tests. Fecal samples collected, 16S ribosomal RNA gene sequencing was performed detect differences composition among sham, non-POD,...
Abstract Background Patients suffering from chronic pain often also exhibit depression symptoms. Soluble epoxide hydrolase (sEH) inhibitors can decrease blood levels of inflammatory cytokines. However, whether inhibiting sEH signaling is beneficial for the comorbidity and unknown. Methods According to a sucrose preference test (SPT), spared nerve injury (SNI) mice were classified into with or without an anhedonia phenotype. Then, protein expression cytokines assessed in selected tissues....
A noninvasive and easy-operation measurement of the heart rate has great potential in home healthcare. We present a simple high running efficiency method for measuring from video. By only tracking one feature point which is selected small ROI (Region Interest) head area, we extract trajectories this both X-axis Y-axis. After series processes including signal filtering, interpolation, Independent Component Analysis (ICA) used to obtain periodic signal, then can be calculated. evaluated on 10...
Emerging evidence suggests that anesthesia and surgery may induce gut dysbiosis. Gut dysbiosis leads to imbalance in circulating contents of microbiota-derived metabolites disrupts the integrity blood-brain barrier (BBB), contributing postoperative cognitive dysfunction (POCD). The composition microbiota be influenced by various antibiotics. However, how perioperative use antibiotics affects POCD needs more explorations. In present study, we explored effect cefazolin, a common antibiotic...
Patients with chronic neuropathic pain (CNP) often complain about their terrible memory, especially the speed of information processing. Accumulating evidence suggests a possible link between gut microbiota and processing as well cognitive function via microbiota-gut-brain axis. This study aimed at exploring fecal microbiome plasma metabolite profiles in middle-aged spared nerve injury (SNI) mice model dysfunction (CD) induced by CNP. The hierarchical cluster analysis performance Morris...
Patients with chronic neuropathic pain frequently suffer from symptoms of anhedonia (loss pleasure), which is a core clinical manifestation depression. Accumulating studies have shown the beneficial effects natural compound sulforaphane (SFN), an activator nuclear factor (erythroid-derived 2)-like 2 (Nrf2), on depression-like phenotype through potent anti-inflammatory effect. However, it unknown whether SFN confers in pain-associated anhedonia. Spared nerve injury (SNI) classical rodent...
Although depressive symptoms including anhedonia (i.e., loss of pleasure) frequently accompany pain, little is known about the risk factors contributing to individual differences in pain-induced anhedonia. In this study, we examined if signaling brain-derived neurotrophic factor (BDNF) and its receptor tropomyosin-receptor-kinase B (TrkB) contribute development neuropathic Rats were randomly subjected spared nerved ligation (SNI) or sham surgery. The SNI rats divided into two groups based on...
This paper aims to study the mechanism of how economic growth and tax reform affect total revenue structure over period (1950-2011). On basis introduction China's previous main measures in reform, this uses methods as descriptive statistics, multi-segment linear regression model principal component analysis analyze mainly from three aspects amount tax, value-added corporate income which are under background reform. The empirical results show that not only has a significant impact on changes,...
We propose a mechanism to achieve real energy spectra via Hermitian subspace in non-Hermitian systems. As an illustrative example, we investigate system composed of two identical Su-Schrieffer-Heeger (SSH) chains connected by lossy site each unit cell. Although the as whole is non-Hermitian, it able support Dirac points that coexist with exceptional points, exactly exhibiting eigenenergies. The and coexistence different singularities are inherited from virtual decoupled subsystems after...
We investigate the second-order topological phases in a two-dimensional ring resonator array with each plaquette occupied by \ensuremath{\pi} gauge flux and imaginary field. The real fields are induced shifting displacement integrating gain or loss into two half perimeters of auxiliary rings. system supports corner modes their emergence being determined non-Bloch invariant due to skin effects. bulk modes, exhibiting effects both trivial nontrivial phases, accumulated at opposite corners...
The relationship between export variety and economic growth has been paid much attention in academia. This paper discusses more deeply the related unrelated growth, rather than mere variety. uses entropy measurement method to measure level of Chinese cities use concept “proximity” proposed by Hidalgo divide Using panel data 252 prefecture-level China from 2000 2011, we attempt explore variety, urban growth. empirical results show that it is not as such, but effects on Export a positive...
Human papillomavirus (HPV) infected keratinocyte dysfunction results in the formation of genital warts, and specific role Sonic hedgehog (SHh) signaling warts remains elusive. Thus, this study aimed to identify correlation between wart SHh signaling.
Compensation systems have been shifting away rapidly from a fixed wage contractual payment basis. Many companies today are creating incentive compensation contracts to reward hardworking employees for jobs well done. Profit-sharing (“sharing contract” thereafter) and target-with-bonus (“target two common performance based contracts, prevalent in business. We theoretically behaviorally studied the sharing target an operational context where firm sets parameters of store manager, after...