- Disaster Response and Management
- Traumatic Ocular and Foreign Body Injuries
- GNSS positioning and interference
- Geophysics and Gravity Measurements
- Nerve Injury and Rehabilitation
- Orthopedic Surgery and Rehabilitation
- Trauma, Hemostasis, Coagulopathy, Resuscitation
- Trauma Management and Diagnosis
- Silicon and Solar Cell Technologies
- Shoulder Injury and Treatment
- Shoulder and Clavicle Injuries
- Trauma and Emergency Care Studies
- Health and Conflict Studies
- Cancer-related cognitive impairment studies
- Multiple Sclerosis Research Studies
- Remote Sensing and LiDAR Applications
- Cardiac Arrest and Resuscitation
- Respiratory Support and Mechanisms
- Parathyroid Disorders and Treatments
- Intensive Care Unit Cognitive Disorders
- Bone fractures and treatments
- 3D Surveying and Cultural Heritage
- History of Medical Practice
- Amyloidosis: Diagnosis, Treatment, Outcomes
- CO2 Reduction Techniques and Catalysts
University Hospital Southampton NHS Foundation Trust
2020-2025
University of Glasgow
2022
Environmental Protection Agency
2021
Pfizer (United States)
2008-2020
University of Southampton
2020
University of Milan
2020
NIHR Southampton Biomedical Research Centre
2020
Lancashire Teaching Hospitals NHS Foundation Trust
2013-2017
James Cook University Hospital
2005-2015
University of Vermont
2008-2015
After the invasion of Iraq in April 2003, coalition forces have remained country a bid to maintain stability and support local security forces. The improvised explosive device (IED) has been widely used by insurgents is leading cause death injury among Coalition troops region.From January 2006, data were prospectively collected on 100 consecutive casualties who either injured or killed hostile action. Mechanism injury, new Injury Severity Score (NISS), International Classification...
A series of Ni-based electrocatalysts, [Ni(7P(Ph)2N(C6H4X))2](BF4)2, featuring seven-membered cyclic diphosphine ligands incorporating a single amine base, 1-para-X-phenyl-3,6-triphenyl-1-aza-3,6-diphosphacycloheptane (7P(Ph)2N(C6H4X), where X = OMe, Me, Br, Cl, or CF3), have been synthesized and characterized. X-ray diffraction studies established that the [Ni(7P(Ph)2N(C6H4X))2](2+) complexes square planar geometry, with bonds to four phosphorus atoms two bidentate ligands. Each is an...
Objective:To compare rates of severe relapse and total direct indirect costs over a 2-year period between US-based employees with multiple sclerosis (MS) who were adherent non-adherent to disease-modifying drugs (DMDs).Methods:Employees ≥1 MS diagnosis (ICD-9-CM: 340.x) DMD pharmacy claim 1/1/2002–12/31/2007 identified from large US administrative claims database. Patients had continuous coverage ≥6 months before (baseline) ≥24 after (study period) their index date (first claim). Adherence...
Coordinate time series are often derived from continuous GPS data processed as discrete 24 hour solutions. Under this regimen, residual semi‐diurnal and diurnal crustal tide signatures under‐sampled, resulting in aliased periodic signals the coordinate series. A secondary aliasing effect, well known satellite altimetry studies but generally ignored analysis, arises repeat period of orbits being longer than Nyquist tidal signatures. This paper derives theoretical periods for these two effects...
We made a prospective study of 58 consecutive Neer II total shoulder replacements in 49 rheumatoid patients. Cemented glenoid and press-fit humeral components had been used. After mean follow-up 9.5 years (7 to 13), 11 patients (15 shoulders) died, one arthrodesed five (five lost follow-up.
Abstract During the recent Gulf war 63 patients with penetrating missile injuries (including 29 Iraqi prisoners of war) underwent operation in a British Army Field Hospital. Their and initial operative management are reported. Fifty-one casualties (81 per cent) suffered an average nine wounds (range 1–45) due to fragmentation weapons, 12 sustained bullet wounds. All were explored following established principles surgery. The extremities involved 48 (76 cent). Eight compound long bone...
Two hundred eleven patients with advanced breast cancer were randomized to receive either epirubicin (E) 50 mg/m2 and prednisolone (LEP) or E 100 (HEP). The intended treatment consisted of 16 courses LEP eight HEP given at 3-weekly intervals. Reasons for stopping early included progressive disease, stable disease without symptomatic improvement, severe toxicity deemed intolerable by the patient physician. Toxicity was recorded response 9-weekly intervals using World Health Organization (WHO)...
We describe 261 peripheral nerve injuries sustained in war by 100 consecutive service men and women injured Iraq Afghanistan. Their mean age was 26.5 years (18.1 to 42.6), the median interval between injury first review 4.2 months (mean 8.4 (0.36 48.49)) follow-up 28.4 20.5 (1.3 64.2)). The lesions were predominantly focal prolonged conduction block/neurapraxia 116 (45%), axonotmesis 92 (35%) neurotmesis 53 (20%) evenly distributed upper lower limbs. Explosions accounted for 164 (63%): 213...
Background Recurrent atherosclerotic plaque growth, restenosis, is a significant clinical problem after interventional procedures. Initiation of restenosis involves activation inflammatory and thrombotic cascades, which are regulated by serine proteinase enzymes inhibitors. We have investigated the use viral inhibitor, SERP-1, to reduce development primary balloon angioplasty. This first experimental report anti-inflammatory protein for prevention atherosclerosis. Methods Results...
Abstract Three cases of plunging ranula are reported and the literature reviewed. Extravasation saliva from sublingual gland due to trauma or obstruction its ducts appears he most likely cause ranula. Available data suggest that submandibular is usually not involved, although at time surgery it may be extremely difficult exclude a origin cyst in neck. Communication between oral cervical components probably occur via hiatus mylohyoid muscle. Such communication passing directly into...
There is marked interindividual variation in serum and tissue angiotensin-converting enzyme (ACE) levels for which the insertion (I)/deletion (D) polymorphism intron 16 of ACE gene a marker. inhibitors have important effects on morbidity mortality heart failure. The influence this response to patients with failure not known. We studied by genotype 34 subjects randomised, double-blind, crossover study comparing 6 weeks lisinopril (10 mg, o.d.) or captopril (25 t.d.s.) 24-h blood pressure (BP)...
The outcomes of 261 nerve injuries in 100 patients were graded good 173 cases (66%), fair 70 (26.8%) and poor 18 (6.9%) at the final review (median 28.4 months (1.3 to 64.2)). initial grades for 42 sutures graft 11 good, 14 17 poor. After subsequent revision repairs seven, neurolyses free vascularised fasciocutaneous flaps 11, 15 nine Pain was relieved 30 36 by repair, repair or neurolysis, when indicated. difference outcome between penetrating missile wounds those caused explosions not...
Abstract One hundred and thirty-seven consecutive acute superficial abscesses were randomly allocated to incision, curettage primary suture without parenteral antibiotics (64 cases) or conventional treatment with drainage dressings (73 cases). Wound healing was faster; 7.0 days: 25.1 days (P<0.01, Wilcoxon's rank sum test), the number of hospital visits smaller; 3.8 visits: 11.1 (P < 0.01) time off work shorter; 4.0 14.1 (P<0.01) in group treated by closure compared...
Abstract Twenty patients with penetrating injuries of the vertebral artery who were treated as emergencies subjected to following operative approaches: five cases, Henry's approach (posterior) and modified (anterior); limited exposure application metal clips; four plugging arterial defect Oxycell or crushed muscle; three control ligatures non-conventional artery; one case, inflation a balloon catheter within canal; repair lacerated first extraosseous part artery. One patient died from...
The new conjugated organometallic polymer (−spacer−C≡C−Pt(PBu3)2−C≡C−)n (3; spacer = para-bis(diphenyl(tetramethyl)quinone diimine) and the cyclic mononuclear model complex, spacer′−C≡C−Pt(PEt3)2−C≡C·CuCl (4; spacer′ ortho-diphenyl-2,3,5,6-tetramethyl-1,4-benzoquinone were synthesized from 1:1 condensation of corresponding diethynyl ligands (2-para 2-ortho (para- ortho-diethynyl-diphenyl-2,3,5,6-tetramethylquinone diimine), respectively), with trans-Pt(PBu3)2Cl2 for 3 cis-Pt(PEt3)2Cl2 4....