Yong Shi

ORCID: 0000-0002-6217-3113
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About
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Research Areas
  • Advanced biosensing and bioanalysis techniques
  • Electrospun Nanofibers in Biomedical Applications
  • RNA Interference and Gene Delivery
  • Biochemical Analysis and Sensing Techniques
  • Pharmacological Receptor Mechanisms and Effects
  • Virus-based gene therapy research
  • Nutrition, Genetics, and Disease
  • Graphene and Nanomaterials Applications
  • Polymer Surface Interaction Studies
  • Bone Tissue Engineering Materials
  • Diet and metabolism studies
  • Pain Mechanisms and Treatments
  • Liver physiology and pathology
  • Drug-Induced Hepatotoxicity and Protection
  • Neuropeptides and Animal Physiology
  • Stress Responses and Cortisol
  • Carbon and Quantum Dots Applications
  • Liver Disease Diagnosis and Treatment
  • Polymer Nanocomposite Synthesis and Irradiation
  • Genetic Associations and Epidemiology
  • Biochemical effects in animals

Nanjing Drum Tower Hospital
2023-2024

Yangtze University
2024

Shaanxi University of Chinese Medicine
2024

Nanjing University
2023

Wuhan Polytechnic University
2023

Nanjing Medical University
2023

Nantong University
2023

Background Previous studies have emphasized the association between intake of artificial sweeteners (AS) and type 2 diabetes mellitus (T2DM), but causative relationship remains ambiguous. Methods This study employed univariate Mendelian randomization (MR) analysis to assess causal link AS from various sources T2DM. Linkage disequilibrium score (LDSC) regression was used evaluate correlation phenotypes. Multivariate mediation MR were applied investigate confounding factors mediating effects....

10.1371/journal.pone.0287496 article EN cc-by PLoS ONE 2024-02-07

Massive periosteal defects often significantly impair bone regeneration and repair, which have become a major clinical challenge. Unfortunately, current engineered materials can hardly currently focus on achieving high tissue adhesion property, being suitable for cell growth, inducing orientation concurrently to meet the properties of nature periosteum. Additionally, preparation oriented surface nanotopography relies professional equipment. In this study, inspired by collagen structure...

10.1021/acsami.3c07561 article EN ACS Applied Materials & Interfaces 2023-09-25

Abstract Diabetic neuropathic pain (DNP) is a common complication of diabetes mellitus (DM) and characterized by spontaneous neuroinflammation. The Sigma-1 receptor (Sig-1R) has been proposed as target for analgesic development. It anti-inflammatory properties found to regulate DNP. However, it not known whether Sig-1R can ameliorate pathological neuroinflammation in present study used rat model DNP highly selective agonist assess the effects protein on rats with type 2 mellitus. were...

10.21203/rs.3.rs-4105810/v1 preprint EN cc-by Research Square (Research Square) 2024-03-28

Abstract Purpose Investigate the protective effect and mechanism of Puerarin (PU) against Dioscorea bulbifera L. (DB)-induced liver injury. Materials methods The PU DB-induced injury was evaluated by present animal experiment, which assessed pathological changes in mice detected Alanine aminotransferase (ALT), Aspartate (AST), Alkaline phosphatase (AKP), as well inflammation oxidative stress-related indexes. Finally, transcription expression related proteins were using western blot...

10.1093/jpp/rgae123 article EN Journal of Pharmacy and Pharmacology 2024-09-13
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