A5046684555- Osteoarthritis Treatment and Mechanisms
- High voltage insulation and dielectric phenomena
- Intermetallics and Advanced Alloy Properties
- Periodontal Regeneration and Treatments
- Knee injuries and reconstruction techniques
- Ferroptosis and cancer prognosis
- Advanced Sensor and Energy Harvesting Materials
- Solidification and crystal growth phenomena
- Catalytic Processes in Materials Science
- Cancer-related molecular mechanisms research
- Mitochondrial Function and Pathology
- Aerosol Filtration and Electrostatic Precipitation
- Plasma Applications and Diagnostics
- Advanced materials and composites
- MXene and MAX Phase Materials
- Advanced Semiconductor Detectors and Materials
- Total Knee Arthroplasty Outcomes
- Plasma Diagnostics and Applications
- Phagocytosis and Immune Regulation
- Smart Agriculture and AI
- Titanium Alloys Microstructure and Properties
- CCD and CMOS Imaging Sensors
- Metallurgical and Alloy Processes
- Electrostatic Discharge in Electronics
- Power Transformer Diagnostics and Insulation
Shanghai Jiao Tong University
2020-2025
Shanghai Sixth People's Hospital
2020-2025
Second Affiliated Hospital of Xi'an Jiaotong University
2025
Sun Yat-sen University Cancer Center
2023-2024
Sun Yat-sen University
2023-2024
Minzu University of China
2024
Institute of Modern Physics
2024
State Key Laboratory of Oncology in South China
2023
Institute of Electrical Engineering
2018-2019
Chinese Academy of Sciences
2005-2019
Abstract Transcortical vessels (TCVs) provide effective communication between bone marrow vascular system and external circulation. Although osteocytes are in close contact with them, it is not clear whether regulate the homeostasis of TCVs. Here, we show that maintain normal network TCVs by transferring mitochondria to endothelial cells TCV. Partial ablation causes TCV regression. Inhibition mitochondrial transfer conditional knockout Rhot1 also leads regression network. By contrast,...
Mosaic transplantation using autologous osteochondral graft (AOCG) is an effective treatment for lesion however, at the sacrifice of irreversible damage to donor articular surface. Costal cartilage hyaline and has been utilized as a source in various surgeries. This study investigates use costal (ACCG) treating femoral head defects swine model. Osteochondral were surgically induced heads one-year-old Bama pigs regardless sex. The divided into Defect group without grafting (n = 6), grafted...
Surface charge accumulation of polymer insulating materials is harmful to the safe operation electrical equipment, especially under DC electric field excitation. In order ensure safety and stable HVDC power system such as Gas-insulated transmission line, it necessary understand influence surface on flashover improve dynamic characteristics. this paper, Epoxy resin (EP) deposited by SiO <sub xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">x</sub> thin...
Apoptosis has long been recognized as a significant mechanism for inhibiting tumor formation, and plethora of stimuli can induce apoptosis during the progression treatment tumors. Moreover, tumor-derived apoptotic extracellular vesicles (apoEVs) are inevitably phagocytosed by live cells, promoting heterogeneity. Understanding which apoEVs regulate cells is imperative enhancing our knowledge metastasis recurrence. Herein, we conducted series in vivo vitro experiments, report that promoted...
<title>Abstract</title> Background: Cancer remains a leading cause of female mortality worldwide, especially in low- and middle-income countries. While lifestyle contributes to cancer causation, the extent its burden on women across different populations unclear. Method: We conducted study investigate role six factors—low physical activity, alcohol consumption, high fasting plasma glucose, dietary, tobacco, body-mass index (BMI)—in among globally, regionally, nationally from 1990 2021....
Reduction quality is associated with fracture prognosis. Displaced subcapital femoral neck has highest possibility of avascular necrosis head and non-union among the fractures, which commonly necessitate revisions or hip replacement. This study introduces for first time using arthroscope to directly visualize assist reduction displaced when closed unsatisfactory. Due minimally invasive advantage arthroscopic assistance, radiation exposure intraoperative bleeding can be reduced, open avoided...
Cartilage tissue engineering faces challenges related to the use of scaffolds and limited seed cells. This study aims propose a cost-effective straightforward approach using costal chondrocytes (CCs) as an alternative cell source overcome these challenges, eliminating need for special culture equipment or scaffolds. CCs were cultured at high density with without ascorbic acid treatment, serving experimental control groups, respectively. Viability tissue-engineered constructs (TEC) formation...
Abstract Background Seeding cells are key factors in cell-based cartilage tissue regeneration. Monoculture of either chondrocyte or mesenchymal stem has several limitations. In recent years, co-culture strategies have provided potential solutions. this study, directly co-cultured rat costal chondrocytes (CCs) and human Wharton’s jelly (hWJMSCs) were evaluated as a candidate to regenerate articular cartilage. Methods Rat CCs with hWJMSCs pellet model at different ratios (3:1, 1:1, 1:3) for 21...
Serine protease inhibitors clade B serpins (SERPINBs) are the largest subclass of inhibitors, once thought as a tumor suppressor gene family. However, some SERPINBs exhibit functions unrelated to inhibition catalytic activity.The Cancer Genome Atlas (TCGA), Gene Expression Omnibus (GEO), Set Analysis (GSCA), and cBioPortal databases were utilized investigate expression, prognostic correlation, genomic variation in 33 cancer types. We also conducted comprehensive transcriptome analysis...
Costal chondrocytes (CCs), as a promising donor cell source for cell-based therapy cartilage repair, have strong tendency of hypertrophy and calcification, which limited CCs from further application in regenerative medicine. Synovium-derived stromal cells (SDSCs), shown their beneficial effect to maintain phenotype. This study aims investigate whether SDSCs could help chondrogenic phenotype suppress hypertrophic differentiation repairs.CCs were directly cocultured with pellet or indirectly...
Purification and Characterization of ETF-RO 20361tied by high pressure liquid chromatography as described previously (16).2,3-Dimethoxy-5-methyl-6-pentyl-1,4-benzoquinone (DPB) antisera to the beef heart ETF-UO were a generous gift Dr. Brian Ackrell, University California,
Both atmospheric pressure dielectric barrier discharge (AP-DBD) deposition and direct fluorination are effective methods to modify the surface electrical properties of polymer insulation. To investigate charge decay Al <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> O xmlns:xlink="http://www.w3.org/1999/xlink">3</inf> -filled epoxy resin (ER) prepared by AP-DBD treatments, before after drying, samples were studied under various treatment...
Both atmospheric pressure dielectric barrier discharge (AP-DBD) deposition and direct fluorination are effective methods to modify the surface electrical properties of polymer insulation. To investigate charge decay Al <inf xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">2</inf> O xmlns:xlink="http://www.w3.org/1999/xlink">3</inf> -filled epoxy resin (ER) prepared by AP-DBD treatments, before after drying, samples were studied under various treatment...
Summary Acceptor‐sensitised 3‐cube fluorescence resonance energy transfer (FRET) imaging (also termed as E‐FRET imaging) is a popular intensity‐based FRET quantification method. Here, an automated microscope with user‐friendly interfaces was set up for dynamical online quantitative live‐cell imaging. This reduces the time of from 12 to 3 s. After locating cells, calibration and cells can be performed automatically by clicking ‘Capture’ button on interfaces. living expressing different tandem...
Recent studies have highlighted the combination of activation host immunogenic cell death (ICD) and tumor-directed cytotoxic strategies. However, overall multiomic analysis intrinsic ICD property in lung adenocarcinoma (LUAD) has not been performed. Therefore, aim this study was to develop an ICD-based risk scoring system predict survival (OS) immunotherapeutic efficacy patients. In our study, both weighted gene co-expression network (WGCNA) LASSO-Cox were utilized identify ICDrisk subtypes...
Abstract The 2-methyl branched-chain enoyl-CoA reductase plays a pivotal role in the reversal of beta-oxidation operating anaerobic mitochondria parasitic nematode Ascaris suum. An affinity-purified polyclonal anti-serum against was used to screen cDNA library constructed lambda gt11 with poly(A)+ RNA from adult A. suum muscle. A 1.2-kilobase partial clone isolated, subcloned, and sequenced both directions. Additional sequence at 5' end mRNA determined by RACE (rapid amplification ends)...
Comb-like CdxZn1-xS nanostructures have been synthesized by one-step metallo-organic chemical vapor deposition (MOCVD). The microstructure and composition were characterized analytical transmission electron microscopy (TEM). ribbon of the comb-like structure is along [2-1-10] (the a-axis), nanotips are [0001] c-axis). atomic location channeling-enhanced microanalysis (ALCHEMI) technique was used to determine polarity crystal via energy-loss spectroscopy (EELS). thickness dependence,...