A5081109205- Diabetes Treatment and Management
- Diabetes Management and Research
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Diabetes Management and Education
- Health Systems, Economic Evaluations, Quality of Life
- Pharmacology and Obesity Treatment
- Chronic Disease Management Strategies
- COVID-19 and healthcare impacts
- Pulmonary Hypertension Research and Treatments
- Healthcare cost, quality, practices
- Atrial Fibrillation Management and Outcomes
- Diabetes and associated disorders
- Adipokines, Inflammation, and Metabolic Diseases
- Metabolism, Diabetes, and Cancer
- Sexual function and dysfunction studies
- Nosocomial Infections in ICU
- Advanced Causal Inference Techniques
- Vitamin D Research Studies
- Pneumonia and Respiratory Infections
- Sexuality, Behavior, and Technology
- Machine Learning in Materials Science
- Healthcare Systems and Challenges
- Seismic Waves and Analysis
- Venous Thromboembolism Diagnosis and Management
- Global Health Care Issues
Primary Health Care
2021-2023
University College London
2016-2023
Central University of Himachal Pradesh
2023
National Institute for Health and Care Excellence
2022
Public Health England
2022
Gandhi Medical College
2012-2020
St Thomas' Hospital
2015
King's College London
2015
King's College Hospital
2015
Guy's and St Thomas' NHS Foundation Trust
2015
Objective To investigate trends in incident and prevalent diagnoses of type 2 diabetes mellitus (T2DM) its pharmacological treatment between 2000 2013. Design Analysis longitudinal electronic health records The Health Improvement Network (THIN) primary care database. Setting UK care. Participants In total, we examined 8 838 031 individuals aged 0–99 years. Outcome measures incidence prevalence T2DM 2013, the effect age, sex social deprivation on these were examined. Changes prescribing...
Aims/Hypothesis: Type 2 diabetes mellitus is associated with high levels of disease burden, including increased mortality risk and significant long-term morbidity. The prevalence differs substantially among ethnic groups. We examined the type diagnoses in UK primary care setting. Methods: analysed data from 404,318 individuals Health Improvement Network database, aged 0–99 years permanently registered general practices London. association between ethnicity 2013 was estimated using a logistic...
Background: Research into diabetes mellitus (DM) often requires a reproducible method for identifying and distinguishing individuals with type 1 DM (T1DM) 2 (T2DM). Objectives: To develop to identify T1DM T2DM using UK primary care electronic health records. Methods: Using data from The Health Improvement Network database, we developed two-step algorithm. first algorithm step identified potential or based on diagnostic records, treatment, clinical test results. We excluded records rarer...
Abstract: Observational studies which evaluate effectiveness are often viewed with skepticism owing to the fact that patients not randomized treatment, meaning results more prone bias. Therefore, controlled trials remain gold standard for evaluating treatment effectiveness. However, it is always possible conduct trials. This may be due financial constraints, example, in identifying funding a trial medicines have already gained market authorization. There can also challenges recruitment, of...
To describe recent trends in the incidence of clinically diagnosed type 2 diabetes and pre-diabetes people seen UK general practice.
Background The COVID-19 pandemic has disrupted healthcare activity across a broad range of clinical services. NHS stopped non-urgent work in March 2020, later recommending services be restored to near-normal levels before winter where possible. Aim To describe changes the volume and variation coded general practice six areas: cardiovascular disease, diabetes, mental health, female reproductive screening related procedures, processes medication. Design setting With approval England, cohort...
Objective To compare real-world effectiveness and safety of direct oral anticoagulants (DOACs) in patients with nonvalvular atrial fibrillation (AFib) for prevention stroke. Study design setting A comparative cohort study UK general practice data from The Health Improvement Network database. Participants interventions Before matching, 5655 ≥18 years AFib who initiated at least one DOAC between 1 July 2014 31 December 2020 were included. DOACs interest included apixaban, rivaroxaban, edoxaban...
Heath Impact Assessment (HIA) in spatial planning can influence wider determinants and prevent ill-health, promote good health reduce inequalities. They remain underutilised England, partly due to inadequate workforce training. This study sought identify the training needs of Public Health Professionals, Planners Practitioners England 2021.Cross-sectional survey.A survey was undertaken ascertain their needs. Descriptive statistics, frequency tables charts summarised feedback.76% (68) 90...
Abstract Background The COVID-19 pandemic has disrupted healthcare activity across a broad range of clinical services. NHS stopped non-urgent work in March 2020, later recommending services be restored to near-normal levels before winter where possible. Aims Using routinely collected data, our aim was describe changes the volume and variation coded general practice in: (i) cardiovascular disease, (ii) diabetes, (iii) mental health, (iv) female reproductive (v) screening, (vi) processes...
Abstract Introduction Depression is a common comorbidity in people with type 2 diabetes and it associated poorer outcomes. There limited data on the treatments used for depression this population. The aim of study was to explore rates initiation antidepressant prescriptions UK identify those most at risk needing such treatment. Research Design Methods This retrospective cohort using from IQVIA Medical Data (IMRD)‐UK data. general practices IMRD‐UK between January 2008 December 2017 were...
Individuals with type 2 diabetes (T2D) have a twofold increased risk for cardiovascular events (CVE), and CVE is responsible nearly 80% of the mortality. Current treatment guidelines state that individuals should immediately initiate antidiabetic risk-factor management from T2D diagnosis. However, evidence base sparse, randomized trials are unlikely to be conducted. We examined impact being eligible treatment, as determined by threshold HbA1c ≥6.5% (≥48 mmol/mol), on all-cause mortality CVE....
Background: Di-peptidyl peptidase-4 inhibitors when used as monotherapy or in combination with other drugs such metfomin, thiazolidinedione sulphonylurea are effective and well tolerated diabetes management. The aim was to evaluate the safety efficacy of sitagliptin compared glimepiride a dual therapy for treatment type-2 patients inadequately controlled metformin.Methods: It an observational, open, comparative multiple follow up study, included 70 visiting department medicine pharmacology...
two common anti-diabetic treatments used are sitagliptin and sulphonylureas however evidence examining their comparative effectiveness in older people is limited.to evaluate of vs when added to metformin (aged ≥75) younger (18-75).retrospective cohort study.UK Primary Care.2,904 individuals prescribed (223 aged≥75) 13,683 (1,725 aged ≥75).multivariable regression analyse difference HbA1c weight, 12 months after add-on initiation proportion achieving different glycaemic targets.after...
DPP-4 inhibitors (DPP-4i) and sulphonylureas remain the most widely prescribed add-on treatments after metformin. However, there is limited evidence from clinical practice comparing major adverse cardiovascular events (MACE) in patients these treatments, particularly among those without prior history of MACE vulnerable population groups. Using electronic health records UK primary care, we undertook a retrospective cohort study with people diagnosed type-2 diabetes mellitus, incidence...
This article provides the context for ambition outlined in National Institute Health and Care Excellence (NICE) 2021-2026 strategy to 'lead globally on potential include environmental impact data its guidance reduce carbon footprint of health care'. Anthropogenic changes pose a catastrophic risk human health, with widen national global inequalities. Recognising fact that NICE influences way care is delivered consequent impact, has included sustainability among strategic priorities. outlines...
Introduction: Nosocomial infection is a critical issue among intubated patients which responsible for significant morbidity and mortality of these patients. One the most important types this pneumoia commonly occurs in relation to endotracheal tube mechanical ventilation named ventilator associated pneumonia. .study presents common microorganisms colonized from hospitalized our setup their antibiotic sensitivity pattern. Methods: 100 who are admitted emergency medical ward Hamidia Hospital...
Improvement in technology has changed the techniques and pattern of examination physical evidences.The based gazettes like PDA, Computer digital camera improved process speed file-work while examination.Two different types case exhibits their physics point-of-view, how changes hierarchy old pattern.