A5009128908- Cardiomyopathy and Myosin Studies
- Muscle Physiology and Disorders
- Atrial Fibrillation Management and Outcomes
- Mechanical Circulatory Support Devices
- Atherosclerosis and Cardiovascular Diseases
- Cardiovascular Function and Risk Factors
- Cardiac Arrhythmias and Treatments
- Heart Failure Treatment and Management
- Cardiovascular Issues in Pregnancy
- Cell Adhesion Molecules Research
- Acute Myocardial Infarction Research
- Child Nutrition and Feeding Issues
- Genetic Neurodegenerative Diseases
- Gout, Hyperuricemia, Uric Acid
- Lipid metabolism and biosynthesis
- Endoplasmic Reticulum Stress and Disease
- Gastrointestinal Bleeding Diagnosis and Treatment
- Inflammasome and immune disorders
- 3D Printing in Biomedical Research
- Tissue Engineering and Regenerative Medicine
- Gastroesophageal reflux and treatments
- Cardiovascular Effects of Exercise
- Protease and Inhibitor Mechanisms
- Synthesis and Biological Evaluation
- Antiplatelet Therapy and Cardiovascular Diseases
Azienda Ospedaliero Universitaria Maggiore della Carita
2025
Università degli Studi del Piemonte Orientale “Amedeo Avogadro”
2025
Centro Cardiologico Monzino
2024
Università Cattolica del Sacro Cuore
2020-2022
Agostino Gemelli University Polyclinic
2020-2022
Istituti di Ricovero e Cura a Carattere Scientifico
2020-2022
Abstract Introduction In recent years, there has been a significant increase in the use of permanent pacemakers (PPM). Endocardial leads can induce or worsen tricuspid regurgitation (TR) when they interfere with valve (TV) leaflets motion. Additionally, right ventricular pacing also TR and mitral (MR). Purpose We aimed to assess: 1) feasibility utilizing 3D transthoracic echocardiography (TTE) visualize PPM lead position, 2) prevalence different positions relative TV leaflets, 3) short-term...
Duchenne muscular dystrophy (DMD) is an X-linked recessive neuromuscular disorder, characterized by significant long-term cardiac involvement. Dilated cardiomyopathy (DCM) the main cause of death in DMD, and angiotensin-converting enzyme inhibitors (ACEi) beta-blockers (BB) are first-line treatments DCM. It unknown whether angiotensin receptor-neprilysin inhibitor (ARNi) could provide greater benefits this setting. Our aim to assess ARNi use may prevent deterioration ejection fraction (EF)...
Aims The ORal anticoagulants In fraGile patients with percutAneous endoscopic gastrostoMy and atrIal fibrillation (ORIGAMI) study investigates the safety efficacy of Edoxaban administered via PEG in atrial a clinical indication for long-term anticoagulation. Design this prospective, single-centre observational study, 12 PEG-treated to anticoagulation will receive edoxaban be followed up 6 months. Plasma antifactor Xa activity concentrations assessed. Thromboembolic (ischaemic stroke,...
Extensive data support the superior safety without any trade-off in efficacy of direct oral anticoagulants (DOACs) compared to vitamin K antagonists (VKA) patients with nonvalvular atrial fibrillation, deep venous thrombosis or pulmonary embolism. Whether DOACs may be successfully used treat complex and fragile percutaneous endoscopic gastrostomy (PEG) remains proven. The purpose this pilot study was evaluate feasibility, anticoagulant effect, preliminary safety/efficacy profile edoxaban...
Abstract Aims Randomized trials support the safety and efficacy of direct oral anticoagulants (DOACs) vs. vitamin K antagonists (VKA) in patients with nonvalvular atrial fibrillation (AF), leading to increased use these compounds. Crushed forms DOACs have shown be reliable, but evidence supporting percutaneous endoscopic gastrostomy (PEG) delivery is lacking. PEG a long-term option for enteral food drug unable maintain intake, bypassing risks disadvantages parenteral nutrition. We...
Edoxaban proved to be safe and effective also in fragile patients, but its administration through percutaneous endoscopic gastrostomy (PEG) has not been previously investigated. The purpose of this study was evaluate the feasibility preliminary safety efficacy profiles edoxaban administered via PEG patients with an indication for long-term oral anticoagulation.ORIGAMI a prospective, single-arm, observational (NCT04271293). Patients anticoagulation were prospectively enrolled. Crushed at...
Abstract Aims Perilipin 2 (PLIN2), a protein associated with intracellular lipid droplets (LDs), is involved in metabolism of macrophages resident atherosclerotic plaques and its up-regulation leads to LDs accumulation. enlargement results the macrophage transformation into foam cells, key step for onset atherosclerosis. In present study, we investigated role PLIN2 regulation mechanisms atherosclerosis plaque instability patients diagnosis ST-elevation myocardial infarction (STEMI) stable...