A5038472497- Cardiomyopathy and Myosin Studies
- Cardiovascular Function and Risk Factors
- Cardiac pacing and defibrillation studies
- Lysosomal Storage Disorders Research
- Amyloidosis: Diagnosis, Treatment, Outcomes
- Cardiovascular Effects of Exercise
- Cardiac Arrhythmias and Treatments
- Cardiac electrophysiology and arrhythmias
- Cardiac Imaging and Diagnostics
- Parathyroid Disorders and Treatments
- Viral Infections and Immunology Research
- Cardiac Structural Anomalies and Repair
- COVID-19 Clinical Research Studies
- Cardiovascular Issues in Pregnancy
- Antiplatelet Therapy and Cardiovascular Diseases
- Intensive Care Unit Cognitive Disorders
- Advanced MRI Techniques and Applications
- Trypanosoma species research and implications
- Atrial Fibrillation Management and Outcomes
- Long-Term Effects of COVID-19
- Parkinson's Disease Mechanisms and Treatments
- Heart Rate Variability and Autonomic Control
- Acute Myocardial Infarction Research
- Sleep and Work-Related Fatigue
- Glycogen Storage Diseases and Myoclonus
Azienda Ospedaliero-Universitaria Careggi
2016-2025
Ospedale San Donato
2023-2025
Florence (Netherlands)
2025
University of Florence
2018-2024
Meyer Children's Hospital
2023
Politecnico di Milano
2006-2009
Luigi Sacco Hospital
1990-1992
University of Milan
1990
BackgroundAtrial fibrillation (AF) is common in patients with cardiac amyloidosis (CA) and a significant risk factor for heart failure hospitalization thromboembolic events.Objective: to investigate the atrial electro-functional predictors of incident AF CA.MethodsA multicenter, observational study performed 4 CA referral centers including sinus rhythm light-chain (AL) transthyretin (ATTR) undergoing electrocardiogram (ECG) magnetic resonance (CMR). The primary endpoint was new-onset...
Patients with hypertrophic cardiomyopathy (HCM) are at increased risk of stroke, but the incidence and factors associated cardioembolic events in HCM patients without atrial fibrillation (AF) remain unresolved. We determined stroke sinus rhythm (SR) monitored a cardiac implantable electronic device (CIED).All consecutive diagnosed referred to CIED implantation >16 years diagnosis ≥ 1 year follow-up post were retrospectively reviewed. Severe LA dilatation was defined as ≥48 mm. stratified by...
Hypertrophic cardiomyopathy (HCM) is the most prevalent genetically inherited cardiovascular disorder in adults and a significant cause of heart failure sudden cardiac death. Historically, atrial fibrillation (AF) has been considered critical aspect HCM patients as it marker disease progression, escalates frequency hospitalizations, increases risk thromboembolic events worsens quality life outcome. Increasing evidence suggests that AF result subtle, long-standing process which starts early...
Abstract Background Hemodynamic force (HDF) analysis allows non-invasive measurement of intraventricular pressure gradients, portraying cyclic spatial-temporal interaction between blood and tissues. Impaired HDFs have been implicated in early detecting adverse cardiac remodelling treatment response various cardiovascular disorders, providing insights into physiology not offered by traditional imaging (1). Mainly explored heart failure, HDF has previously applied to hypertrophic...
Fabry disease is an X-linked lysosomal storage disorder caused by deficient activity of the enzyme α-galactosidase A, leading to accumulation globotriaosylceramide in various tissues, including heart. Cardiac involvement a prominent feature and major cause morbidity mortality disease, manifesting as left ventricular hypertrophy, myocardial ischaemia, heart failure, arrhythmias. Secondary mechanisms, triggered storage, contribute damage, particular, inflammation. Early cardiac can be subtle,...
Patients with repaired tetralogy of Fallot (rTOF) are commonly followed MRI and frequently develop right ventricular (RV) dysfunction, which can be severe enough to impact left (LV) function in some patients. In this study, we sought characterize patterns LV dysfunction patient population using Deep Learning Synthetic Strain (DLSS), a fully automated deep learning algorithm capable measuring regional strain dyssynchrony. We retrospectively collected cine SSFP images from multi-institutional...
To assess the association of pre-morbid functional status [Barthel Index (BI)] and frailty [modified Frailty (mFI)] with in-hospital mortality a risk scoring system developed for COVID-19 in patients ≥75 years diagnosed COVID-19.Retrospective bicentric observational study.Data on consecutive aged admitted at 2 Italian tertiary care centers were collected from February 22 to May 30, 2020.Overall, 221 hospitals study period included analysis. Clinical, (BI), (mFI), laboratory, imaging data...
The CHA2DS2-VASc score predicts stroke in patients with atrial fibrillation and has been reported to have a prognostic role even acute coronary syndrome patients. Takotsubo is condition that mimics may present several complications including stroke. We sought assess the ability of predict adverse events patients.Overall, 371 were enrolled prospective registry. Patients divided into 3 groups according score: Group A (≤1), B (2-3), C (≥4). median was (interquartile range: 2-4). Overall, 9%,...
To assess the feasibility of a newly developed algorithm, called deep learning synthetic strain (DLSS), to infer myocardial velocity from cine steady-state free precession (SSFP) images and detect wall motion abnormalities in patients with ischemic heart disease.In this retrospective study, DLSS was by using data set 223 cardiac MRI examinations including SSFP four-dimensional flow (November 2017 May 2021). establish normal ranges, segmental measured 40 individuals (mean age, 41 years ± 17...
This paper describes a method for designing an intelligent system to improve driver safety. A prototype of the system, which was designed by following this method, is presented. Driver physiological data acquired from sensors on steering wheel are correlated, using statistical multivariate analysis, driver's vigilance level, evaluated polysomnography. driving simulation conducted with mechanical platform, whose were also and studied same way. The parameters chosen evaluation used first time...