A5103157889- RNA modifications and cancer
- Cancer-related gene regulation
- Intracerebral and Subarachnoid Hemorrhage Research
- Peptidase Inhibition and Analysis
- Ferroptosis and cancer prognosis
- Ion Transport and Channel Regulation
- Cerebrospinal fluid and hydrocephalus
First Affiliated Hospital of Soochow University
2022-2025
Soochow University
2022-2025
Intracerebral hemorrhage (ICH) is a subtype of stroke marked by elevated mortality and disability rates. Recently, mounting evidence suggests significant role ferroptosis in the pathogenesis ICH. Through combination bioinformatics analysis basic experiments, our goal to identify primary cell types key molecules implicated post-ICH. This aims propel advancement research, offering potential therapeutic targets for ICH treatment. Our study reveals pronounced microglia identifies target gene,...
The infiltration of blood components into the brain parenchyma through lymphoid system is an important cause subarachnoid hemorrhage injury. AQP4, a water channel protein located at astrocyte foot, has been reported to regulate blood–brain barrier integrity, and its polarization disrupted after SAH. Neuronal ferroptosis involved in hemorrhage- (SAH-) induced injury, but inducing factors are not completely clear. Transferrin one ferroptosis. This study aimed researching role mechanism AQP4...