A5066120549- Genetic Neurodegenerative Diseases
- Long-Term Effects of COVID-19
- Intracerebral and Subarachnoid Hemorrhage Research
- Cerebrovascular and genetic disorders
- Peripheral Neuropathies and Disorders
- Acute Ischemic Stroke Management
- Autoimmune Neurological Disorders and Treatments
- Visual perception and processing mechanisms
- Gut microbiota and health
- Stroke Rehabilitation and Recovery
- Spatial Neglect and Hemispheric Dysfunction
- Traumatic Brain Injury and Neurovascular Disturbances
- Spatial Cognition and Navigation
- Traumatic Brain Injury Research
- COVID-19 and healthcare impacts
- Visual Attention and Saliency Detection
- Voice and Speech Disorders
- Fetal and Pediatric Neurological Disorders
- Intracranial Aneurysms: Treatment and Complications
- Cardiac Arrest and Resuscitation
- Muscle Physiology and Disorders
- COVID-19 Clinical Research Studies
- Cutaneous Melanoma Detection and Management
- Neurological and metabolic disorders
- Neurological Disorders and Treatments
Privolzhsky Research Medical University
2020-2025
In Alzheimer’s disease (AD), disturbances in spatial orientation and navigation occur even at the pre-dementia stage can have important diagnostic significance, reflecting changes those areas of brain that suffer earlier than others this pathology. However, it is difficult to identify such disorders using classical neuropsychological tests, studies real environment are not readily available routine practice. These difficulties be overcome by researches a virtual environment. The purpose was...
Chronic disorders of consciousness (DOC) represent severe central nervous system damage resulting in long-term disability and a significant burden to healthcare institutions patientsʼ families. DOC develop patients after coma are characterized by the presence wakefulness with complete or almost absence signs awareness. include vegetative state (VS) minimally conscious (MCS). The term prolonged (pDOC) is also used Russian literature describe initial stages chronic DOC. Another clinical...
Paraneoplastic neurological syndromes (PNNS) are disorders due to autoimmune attack on the nervous system, induced by a tumor remote from these structures. The existence of relatively stable associations between syndrome, type antineuronal antibodies (Ab) and nature has been proven. At same time, there no pathognomonic combinations this kind: can be detected in diff erent types tumors syndromes. In addition, level reliability diagnosis PNNS is considered, taking into account phenotype...
Objective. To identify clinical and non-hemorrhagic neuroimaging indicators of probable CAA in patients with acute non-traumatic lobar hematomas. Cerebral amyloid angiopathy (CAA) is a microangiopathy affecting the leptomeningial cortical vessels brain due to deposition pathological b-amyloid them. The most common manifestation hematomas (LH) – spontaneous intracerebral hemorrhages localized between cerebral cortex basal ganglia. LH can also occur hypertensive (hCMA) arterial hypertension....
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Dysimmune polyneuropathies are the etiologically heterogeneous group of diseases with autoimmune damage to peripheral nervous system. The rarity these doesn’t exclude possibility their development or exacerbation in patients infected SARS‑CoV‑2, which will require timely differential diagnosis and urgent specific therapy. article summarizes current information on mechanisms development, clinical features, management acute chronic dysimmune context COVID‑19 pandemic.
Visual object agnosia (VOA) is a loss of the ability to recognize visible objects in patients with intact primary visual functions and absence dementia. The apperceptive associative variants VOA are marked out. thought be due «pre-semantic» impairment information processing. caused by access knowledge about objects, its semantic subtype disintegration this itself. It important diagnose time provide individualized approaches medical rehabilitation patients. Case reports acute ischemic stroke...
The purpose of this study was to evaluate impact cognitive impairments on the upper limb function recovery after acute lacunar stroke (LS). Material and methods. 139 patients (aged from 35 80 y. o.) with LS were examined. Along clinical neurological examination, an evaluated by Action Research Arm Test 9-Hole Peg Test, a status made using Montreal Cognitive Assessment (МоСа) Frontal Battery (FAB). Results. Impaired revealed in 79% LS. After 2 weeks period LS, significant improvement or...
A clinical description of a 28-year-old man with spinal and bulbar muscular atrophy diagnosed on the basis CAG-trinucleotide expansion in gene coding androgen receptor is presented. He exhibited skeletal muscles tongue fasciculations, gynecomastia, increased serum testosterone creatine kinase levels. The peculiarities case were gynecomastia under age 7, development fasciculations at 11 appearance hard muscle stiffness delayed relaxation after voluntary contraction 15, which resembled typical...
A detailed analysis of the neurological disorders «dysarthria–clumsy hand» syndrome (DCHS) is important for its earlier diagnosis. The purpose this study was to evaluate incidence DCHS and range clinical signs, as well degree hand/arm dysfunctions dynamics in patients with acute lacunar stroke (LS). Material methods . 139 LS were examined. Quantitative assessment deficits, such paresis, cerebellar ataxia, apraxia performed using relevant scales. upper limb function assessed by Action...
We report a case of transverse myelitis and Guillain–Barre syndrome (GBS) overlap in the 42-year-old patient with moderate course Coronavirus disease 2019 (С OVID-19). Nasopharyngeal SARS-CoV 2 RT-PCR was positive. Severe neck pain developed this on 5-th day С OVID-19. A few hours later weakness feet arised then spread to thighs arms. Quadriparesis, arefl exia all limbs, sensory loss below level T4 bladder/bowel dysfunction were present. Pyramidal signs negative. There no increase COVID-19...
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is the most prevalent monogenic cerebral small-vessel disease, but doctor’s knowledge in this sphere still insufficient. We aimed to introduce recommendations of European Academy Neurology Russian clinicians because it can help them discover CADASIL time manage patients form disease. present own case report.
A 20-year-old patient was presented with subacute onset of headache, nausea and vomiting. Testing nasal/oropharyngeal swabs indicated the presence SARS-CoV-2 RNA, later antibodies to this virus were found. The treatment in hospital for Coronavirus 19 Disease (COVID-19) provided only temporary relief, then referred Regional Stroke Center (RSC) exclude a subarachnoid hemorrhage. RSC neurologists drew attention multiple skin nevi patient. Brain MRI demonstrated abnormal T1 hyperintensity brain...
The aim of the study was to analyze stroke case fatality in regional center (RSC) during COVID-19 pandemic, order plan prevention measures for reduction mortality. A retrospective comparative analysis medical records patients who died October-November 2019 and 2020, i.e. before Coronavirus Disease Pandemic (COVID-19) conducted. age patients, NIHSS score Glasgow coma at admission did not differ on average 2020. Also, there were no differences incidence ischemic hemorrhagic stroke, rate early...