A5040103756- Endodontics and Root Canal Treatments
- Dental materials and restorations
- Oral and Maxillofacial Pathology
- Bone and Dental Protein Studies
- Bone Tissue Engineering Materials
- Dental Radiography and Imaging
Tokyo Medical and Dental University
2018-2020
The University of Tokyo
2018-2020
King Abdulaziz University
2020
This study examined the effects and mechanisms of strontium ranelate (SrRn)-a drug used to treat osteoporosis-on proliferation differentiation/mineralization cloned dental pulp-like cells (mouse papillae cells; MDPs). It also determined whether topical application SrRn exposed pulp tissue promotes formation mineralized in vivo. The MDPs were cultured with or without SrRn, cell proliferation, odonto-/osteoblastic gene expression, nodule formation, Akt phosphorylation evaluated. SrRn-treated...
Surface-reaction-type prereacted glass-ionomer (S-PRG) fillers exhibit bioactive properties by the release of multiple ions. This study examined whether a novel endodontic sealer containing S-PRG (PRG+) has capacity to induce osteoblast differentiation. Kusa-A1 osteoblastic cells were cultured with extracts PRG+, PRG− (an experimental S-PRG-free silica fillers), AH Plus epoxy-resin-based sealer), and Canals N (a zinc-oxide noneugenol sealer). Cell viability mineralized nodule formation...