- Bone health and osteoporosis research
- Bone health and treatments
- Parathyroid Disorders and Treatments
- Vitamin D Research Studies
- Bone Metabolism and Diseases
- Bone and Joint Diseases
- Vitamin C and Antioxidants Research
- Hip and Femur Fractures
- Metabolism, Diabetes, and Cancer
- Thyroid and Parathyroid Surgery
- Medical Imaging and Pathology Studies
- Thyroid Disorders and Treatments
- Connective tissue disorders research
- Growth Hormone and Insulin-like Growth Factors
- Medical Imaging and Analysis
- Alkaline Phosphatase Research Studies
- Nutrition and Health in Aging
- Cardiovascular Function and Risk Factors
- Neuroendocrine Tumor Research Advances
- Bone and Dental Protein Studies
- Genetic Syndromes and Imprinting
- Hormonal and reproductive studies
- Radiopharmaceutical Chemistry and Applications
- Hip disorders and treatments
- Pleural and Pulmonary Diseases
Sapienza University of Rome
2012-2024
Policlinico Umberto I
1990-2018
Surgical Specialties (United States)
2011
Azienda Ospedaliero Universitaria San Giovanni Battista
1998-2003
Istituti di Ricovero e Cura a Carattere Scientifico
2001
Casa Sollievo della Sofferenza
2001
Presidio Ospedaliero
2001
University of Rome Tor Vergata
1997
Istituto di Sessuologia Clinica
1993
University of Florence
1960
In humans, few studies have compared the potencies of ergocalciferol and cholecalciferol in improving maintaining vitamin D status.Our objective was to evaluate effects a single very large dose both calciferols on serum changes 25-hydroxyvitamin [25(OH)D], 1,25-dihydroxyvitamin [1,25(OH)(2)D], ionized calcium, parathyroid hormone (PTH) at baseline, 3, 7, 30, 60 d.This prospective randomized intervention study.The study performed nursing home residence.A total 32 elderly female patients (age...
Abstract. The study was performed on patients with ischaemic cerebral infarction in order to obtain information serial changes of some platelet parameters and test their prognostic significance. Platelet count, obtained within 48 h after infarction, significantly lower than the control group (213611±65652 mm −3 vs . 299525±60611 , P < 0.001), reaching normal level ninth day thereafter. mean volume greater controls (11.26±1.29 fl 8.93±0.93 fl. normalization generally occurred forty‐fifth...
Effects of vitamin D repletion in young people with low status have not been investigated so far.We evaluated the effect a single massive dose cholecalciferol on calcium metabolism at 3, 15, and 30 d, compared to baseline.We conducted prospective intervention study an ambulatory care setting.Forty-eight subjects deficiency participated study.A oral 600,000 IU was administered each subject.We serum changes 25-hydroxyvitamin [25(OH)D], 1,25-dihydroxyvitamin D, calcium, PTH induced by load...
We previously showed that a single high dose of oral (po) cholecalciferol (D₃) sharply increases serum 25-hydroxyvitamin D [25(OH)D].We evaluated the long-term bioavailability and metabolism po or intramuscular (im) ergocalciferol (D₂) D₃.This was prospective intervention study.The study conducted in an ambulatory care setting.Participants were 24 subjects with hypovitaminosis D.A 600,000 IU im D₂ D₃ administered.Serum 25(OH)D 1,25-dihydroxyvitamin [1,25(OH)₂D] measured at baseline days 30,...
To evaluate the prevalence of vertebral (vFr) and non-vertebral (nvFr) fractures in postmenopausal women with primary hyperparathyroidism (PHPT).We studied 98 patients PHPT, divided into 'mild' (M, n = 25) 'non-mild' (NM, 73) sub-groups, according to recently published guidelines (2002), 89 healthy (C) matched for age, years since menopause body mass index. vFr was evaluated a visual semiquantitative method; bone mineral density (BMD) at lumbar spine (LS), femoral sites (femoral neck, FN...
The present study aimed to investigate the prevalence and seasonal variation of hypovitaminosis D (defined as serum 25-hydroxyvitamin level below 30 nmol/l) among healthy subjects hospitalized patients living in central Italy. We studied 297 subjects, 131 February 1997 166 July 1997, subdivided into four groups: (a) young blood donors; (b) postmenopausal women; (c) inpatients with various medical diseases (d) engaged long-term rehabilitation programmes because neurological disorders. In all...
AbstractThe study was carried out to evaluate the clinical validity and usefulness of serum tartrate-resistant acid phosphatase (TRAP) activity determined using an improved spectrophotometric assay. Enzyme measured in 84 normal subjects 109 patients with common metabolic bone diseases.Mean values TRAP male (n= 19; 10.4 ± 2.15 U1-1) were not significantly different from those found female (n=65; 10.8 1.8 U 1-1). In latter group mean raised post-menopausal (10.5 2.0 l-1; p <.0 01) compared...
The possible relationships between biochemical measurements and both densitometric radiographic indexes of skeletal fragility were evaluated in 65 postmenopausal women with monoclonal gammopathy undetermined significance (MGUS). There was a significantly higher prevalence vertebral fractures the MGUS group compared control population (P < or = 0.001). patients then grouped according to presence absence at least one mild fracture. Patients (Fx, n=34) older (62.8 +/- 6.1 years), long-standing...