A5063617296- RNA modifications and cancer
- Bacteriophages and microbial interactions
- MicroRNA in disease regulation
- Probiotics and Fermented Foods
- Total Knee Arthroplasty Outcomes
- Bone fractures and treatments
- SARS-CoV-2 and COVID-19 Research
- Vaccine Coverage and Hesitancy
- Circular RNAs in diseases
- Glycosylation and Glycoproteins Research
- Enzyme-mediated dye degradation
- Elbow and Forearm Trauma Treatment
- SARS-CoV-2 detection and testing
- Cancer Mechanisms and Therapy
- Ubiquitin and proteasome pathways
- Advanced biosensing and bioanalysis techniques
- Misinformation and Its Impacts
- Biochemical and biochemical processes
- Legume Nitrogen Fixing Symbiosis
- RNA regulation and disease
- Patient Satisfaction in Healthcare
- Medicinal Plant Research
- Brucella: diagnosis, epidemiology, treatment
- Hip disorders and treatments
- Lignin and Wood Chemistry
Jilin University
2018-2024
Ferghana Polytechnical Institute
2022-2024
Civil Hospital Karachi
2020-2024
Ferghana State University
2023-2024
Jilin Medical University
2023
MicroRNAs (miRNAs) as small non-coding RNA transcripts bind their complementary sequences in the 3′-untranslated region (3′-UTR) of target messenger RNAs (mRNAs) to regulate expression. It is known that miR-372 belongs miR-371–373 gene cluster and has been found be abnormally expressed a variety cancers, but its precise mechanism cancer remains discovered. In this study, miR-372-3p expression was assessed 153 frozen tissue samples, including primary diagnosed colon matched normal adjacent...
Background:The trend of telemedicine is exponentially increasing worldwide due to the coronavirus disease (COVID-19) pandemic. However, patient satisfaction always a concern regarding use telemedicine.Introduction:The aim this study evaluate perception and level patients toward during pandemic COVID-19 among Pakistani population.Materials Methods:The survey questionnaires were distributed 251 who received consultation in any three specializations: orthopedic, ophthalmology, general medicine....
Transcriptional activation of p21 (cyclin‐dependent kinase inhibitor 1A) due to DNA damage often alters the distribution histone variant H2A.Z at gene. However, whether human INO80 complex regulates changes in promoter is unclear. We show here that expression by doxorubicin (Doxo) U2OS cells required for removal p53‐binding site proximal region (−2.2 kb) promoter. A purified complex, but not INO80E653Q mutant‐complex, which lost DNA‐sliding activity, mainly responsible removing from...
Ramadan fasting is a religious practice observed by millions of Muslims worldwide. Firstly, the experimental studies were searched on different websites like PubMed, Science direct, and google scholar to find out latest research regarding fasting. Studies have shown that influences body weight, blood glucose, insulin, lipid levels, pressure. However, effects mental health specific conditions such as cardiovascular diseases, cancer or metabolic disorders vary depending individual factors....
Both OGT1 (O-linked β-N-acetylglucosamine (O-GlcNAc) transferase isoform 1) and NSL3 (nonspecific lethal protein 3) are crucial components of the MOF (males absent on first)/NSL histone acetyltransferase complex. We previously described how global H4 acetylation levels were modulated by OGT1/O-GlcNAcylation-mediated stability. However, specific modification site its molecular mechanism stability remain unknown. Here, we present evidence from biochemical experiments arguing that...
The SARS-CoV-2 coronavirus outbreak is extremely concerning and poses a threat to the public health system. pathogen that affects people caused fever, dry cough, dizziness severe respiratory disease. By media time, greater than 662 million were infected 6.6 died globally. pandemic was hurt third world countries due weak infrastructure. A timely response crucial for commercially easily accessible resources since an actual emergency does not provide necessary timescale test of innovative ways....
Introduction Zinc oxide nanoparticles (ZnO-NPs) have garnered considerable interest in biomedical research primarily owing to their prospective therapeutic implications combatting pathogenic diseases and microbial infections. The primary objective of this study was examine the biosynthesis zinc nanowhiskers (ZnO-NWs) using chicken egg white (albumin) as a bio-template. Furthermore, aimed explore potential applications ZnO NWs context infectious diseases. Methods synthesized through...
Radial neck fractures with radial head rotation are very rare and extremely difficult to manage. We present the case of an 11-year-old girl who fell on her outstretched left upper extremity damaged elbow in a road traffic accident. An arthrotomy was performed under C-Arm fluoroscope, which confirmed displacement 180° along fracture. The fracture site reduced fixed two Kirschner wires, cutting wire short at its distal end for complete closure. Open reduction internal fixation were followed by...
2 Abstract: This study aimed to propagate starter culture locally for yogurt preparation and conduction of sensory evaluation trials testing the quality developed culture. Experiments were conducted select strains Lactobacillus delbrueckii ssp. bulgaricus Streptococcus thermophilus having most suitable properties yogurt. The selection criteria included lactic acid production ability aroma production. To whey based medium was found successfully support growth desirable bacterial isolates and,...
Human INO80 chromatin remodeling complex (INO80 complex) as a transcription cofactor is widely involved in gene regulation and frequently highly expressed tumor cells. However, few reports exist on the mutual regulatory mechanism between non-coding microRNAs. Herein, we showed evidence that transcriptionally controls microRNA-372 (miR-372) expression through RNA-Seq analysis series of biological experiments. Knocking down multiple subunits complex, including catalytic subunit, YY1, Ies2,...
Background and aim: Brucellosis is one of the world most common zoonotic diseases. The current study was aimed to prepare Rose Bengal Plate Test (RBPT) antigen for diagnosis brucellosis determine its specificity sensitivity. Material methods: plate test prepared from Brucella abortus (B. abortus) strain 99 compared with two commercial antigens sensitivity are determined. Results: were I-ELISA result show that in vitro superior RBPT University Diagnosis Laboratory (UDL) Lahore Pakistan,...
This retrospective case series analyses the clinical and radiological outcomes of displaced proximal humerus fractures treated with PHILOS plate system iliac crest bone autograft. Twenty-six patients humerus, who were autologous grafts from January 2015 to September 2020, included in this study. The inclusion criteria displacement more than 1cm angulation 45 degrees. functional evaluated using DASH constant score. Radiological measured by calculating fracture union. average age cohort was...